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Select item 114994341.

A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6

Lizhe Wang, Yu Wang, Yueyang Li, Li Zhou, Sihan Liu, Yongyi Cao, Yuzhi Li, Shenting Liu, Jiahui Du, Jin Wang, Ting Zhu

J Cancer Res Clin Oncol. 2024; 150(10): 475. Published online 2024 Oct 23. doi: 10.1007/s00432-024-05995-w

PMCID:: PMC11499434

Abstract Article PDF–3.2M

Select item 107253302.

Overexpression of HSPB6 inhibits osteosarcoma progress through the ERK signaling pathway

Liangyu Guo, Kangwen Xiao, Yuanlong Xie, Zhiqiang Yang, Jun Lei, Lin Cai

Clin Exp Med. 2023; 23(8): 5389–5398. Published online 2023 Oct 20. doi: 10.1007/s10238-023-01216-9

PMCID:: PMC10725330

Abstract Article PDF–3.8M

Select item 102207753.

HSPB6 Is Depleted in Colon Cancer Patients and Its Expression Is Induced by 5-aza-2′-Deoxycytidine In Vitro

Bader O. Almutairi, Mikhlid H. Almutairi, Abdulwahed F. Alrefaei, Saad Alkahtani, Saud Alarifi

Medicina (Kaunas) 2023 May; 59(5): 996. Published online 2023 May 21. doi: 10.3390/medicina59050996

PMCID:: PMC10220775

Abstract Article PDF–1.8M

Select item 101415814.

Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ

Phillip Zhu, Stanislau Stanisheuski, Rachel Franklin, Amber Vogel, Cat Hoang Vesely, Patrick Reardon, Nikolai N. Sluchanko, Joseph S. Beckman, P. Andrew Karplus, Ryan A. Mehl, Richard B. Cooley

ACS Cent Sci. 2023 Apr 26; 9(4): 816–835. Published online 2023 Apr 10. doi: 10.1021/acscentsci.3c00191

PMCID:: PMC10141581

Abstract Article PDF–9.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71396916.

Effect of Arginine on Chaperone-Like Activity of HspB6 and Monomeric 14-3-3ζ

Valeriya V. Mikhaylova, Tatiana B. Eronina, Natalia A. Chebotareva, Vladimir V. Shubin, Daria I. Kalacheva, Boris I. Kurganov

Int J Mol Sci. 2020 Mar; 21(6): 2039. Published online 2020 Mar 16. doi: 10.3390/ijms21062039

PMCID:: PMC7139691

Abstract Article PDF–3.2M

Select item 58465517.

Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6^S10F mutant

Guan-Sheng Liu, Hongyan Zhu, Wen-Feng Cai, Xiaohong Wang, Min Jiang, Kobina Essandoh, Elizabeth Vafiadaki, Kobra Haghighi, Chi Keung Lam, George Gardner, George Adly, Persoulla Nicolaou, Despina Sanoudou, Qiangrong Liang, Jack Rubinstein, Guo-Chang Fan, Evangelia G. Kranias

Autophagy. 2018; 14(1): 80–97. Published online 2018 Jan 29. doi: 10.1080/15548627.2017.1392420

PMCID:: PMC5846551

Abstract Article PDF–2.2M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54732469.

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1

Michelle Heirbaut, Frederik Lermyte, Esther M. Martin, Steven Beelen, Frank Sobott, Sergei V. Strelkov, Stephen D. Weeks

J Biol Chem. 2017 Jun 16; 292(24): 9944–9957. Published online 2017 May 9. doi: 10.1074/jbc.M116.773515

PMCID:: PMC5473246

Abstract Article PDF–2.0M

Select item 532151310.

Structural basis for the interaction of a human small heat shock protein with the 14-3-3 universal signaling regulator

Nikolai N. Sluchanko, Steven Beelen, Alexandra A. Kulikova, Stephen D. Weeks, Alfred A. Antson, Nikolai B. Gusev, Sergei V. Strelkov

Structure. Author manuscript; available in PMC 2017 Feb 22.

Published in final edited form as: Structure. 2017 Feb 7; 25(2): 305–316. Published online 2017 Jan 12. doi: 10.1016/j.str.2016.12.005

PMCID:: PMC5321513

Abstract Article PDF–2.2M

Select item 482157911.

Phosphorylated Heat Shock Protein 20 (HSPB6) Regulates Transforming Growth Factor-α-Induced Migration and Invasion of Hepatocellular Carcinoma Cells

Rie Matsushima-Nishiwaki, Hidenori Toyoda, Tomoaki Nagasawa, Eisuke Yasuda, Naokazu Chiba, Seiji Okuda, Atsuyuki Maeda, Yuji Kaneoka, Takashi Kumada, Osamu Kozawa

PLoS One. 2016; 11(4): e0151907. Published online 2016 Apr 5. doi: 10.1371/journal.pone.0151907

PMCID:: PMC4821579

Abstract Article PDF–2.9M

Select item 468896712.

Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter

Laura A. N. Peferoen, Wouter H. Gerritsen, Marjolein Breur, Kimberley M. D. Ummenthum, Regina M. B. Peferoen-Baert, Paul van der Valk, Johannes M. van Noort, Sandra Amor

Acta Neuropathol Commun. 2015; 3: 87. Published online 2015 Dec 22. doi: 10.1186/s40478-015-0267-2

PMCID:: PMC4688967

Abstract Article PDF–2.7M

Select item 461721113.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 442902514.

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

Lydia K. Muranova, Stephen D. Weeks, Sergei V. Strelkov, Nikolai B. Gusev

PLoS One. 2015; 10(5): e0126248. Published online 2015 May 12. doi: 10.1371/journal.pone.0126248

PMCID:: PMC4429025

Abstract Article PDF–4.5M

Select item 442541315.

Identification of peptides in human Hsp20 and Hsp27 that possess molecular chaperone and anti-apoptotic activities

Rooban B. Nahomi, Michael A. DiMauro, Benlian Wang, Ram H. Nagaraj

Biochem J. Author manuscript; available in PMC 2015 May 8.

Published in final edited form as: Biochem J. 2015 Jan 1; 465(1): 115–125. doi: 10.1042/BJ20140837

PMCID:: PMC4425413

Abstract Article PDF–3.5M

Select item 381939216.

Direct Association of Heat Shock Protein 20 (HSPB6) with Phosphoinositide 3-kinase (PI3K) in Human Hepatocellular Carcinoma: Regulation of the PI3K Activity

Rie Matsushima-Nishiwaki, Takashi Kumada, Tomoaki Nagasawa, Mariko Suzuki, Eisuke Yasuda, Seiji Okuda, Atsuyuki Maeda, Yuji Kaneoka, Hidenori Toyoda, Osamu Kozawa

PLoS One. 2013; 8(11): e78440. Published online 2013 Nov 6. doi: 10.1371/journal.pone.0078440

PMCID:: PMC3819392

Abstract Article PDF–466K

Select item 379029217.

Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity

Ying Chen, Li-Na Yang, Li Cheng, Shun Tu, Shu-Juan Guo, Huang-Ying Le, Qian Xiong, Ran Mo, Chong-Yang Li, Jun-Seop Jeong, Lizhi Jiang, Seth Blackshaw, Li-Jun Bi, Heng Zhu, Sheng-Ce Tao, Feng Ge

Mol Cell Proteomics. 2013 Oct; 12(10): 2804–2819. Published online 2013 Jul 3. doi: 10.1074/mcp.M112.025882

PMCID:: PMC3790292

Abstract Article PDF–2.6M

Select item 349894318.

The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser₁₆

Helen V. Edwards, John D. Scott, George S. Baillie

Biochem J. Author manuscript; available in PMC 2012 Nov 15.

Published in final edited form as: Biochem J. 2012 Sep 15; 446(3): 437–443. doi: 10.1042/BJ20120570

PMCID:: PMC3498943

Abstract Article PDF–2.2M

Select item 341324319.

Monomeric 14-3-3ζ Has a Chaperone-Like Activity and Is Stabilized by Phosphorylated HspB6

Nikolai N. Sluchanko, Natalya V. Artemova, Maria V. Sudnitsyna, Irina V. Safenkova, Alfred A. Antson, Dmitrii I. Levitsky, Nikolai B. Gusev

Biochemistry. 2012 Aug 7; 51(31): 6127–6138. Published online 2012 Jul 13. doi: 10.1021/bi300674e

PMCID:: PMC3413243

Abstract Article PDF–3.4M

Select item 329967920.

Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2

Xiaowei Zhang, Xiaohong Wang, Hongyan Zhu, Evangelia G. Kranias, Yaoliang Tang, Tianqing Peng, Jiang Chang, Guo-Chang Fan

PLoS One. 2012; 7(3): e32765. Published online 2012 Mar 12. doi: 10.1371/journal.pone.0032765

PMCID:: PMC3299679

Abstract Article PDF–2.2M

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