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Select item 109987941.

NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16

Danfeng Guo, Ming Zhang, Tingju Wei, Xiaodan Zhang, Xiaoyi Shi, Hongwei Tang, Mingjie Ding, Jie Li, Shuijun Zhang, Wenzhi Guo

Cell Mol Life Sci. 2024 Dec; 81(1): 167. Published online 2024 Apr 6. doi: 10.1007/s00018-024-05182-7

PMCID:: PMC10998794

Abstract Article PDF–13M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101522373.

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma

Xiang Li, Chenxing Wang, Hang Zhang, Yangjie Li, Deqiang Hou, Dingshan Liu, Rongyao Xu, Jie Cheng, Laikui Liu, Yu Fu, Jinhai Ye, Hongbing Jiang

Cancer Res. 2023 May 2; 83(9): 1459–1475. Published online 2023 Feb 22. doi: 10.1158/0008-5472.CAN-22-2585

PMCID:: PMC10152237

Abstract Article PDF–22M

Select item 100729064.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 95239825.

TRIM3 and TRIM16 as potential tumor suppressors in breast cancer patients

Mohammad Reza Roshanazadeh, Maryam Adelipour, Arash Sanaei, Hadi Chenane, Mojtaba Rashidi

BMC Res Notes. 2022; 15: 312. Published online 2022 Sep 30. doi: 10.1186/s13104-022-06193-y

PMCID:: PMC9523982

Abstract Article PDF–994K

Select item 93383136.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 89736368.

CircPTK2 inhibits cell cisplatin (CDDP) resistance by targeting miR-942/TRIM16 axis in non-small cell lung cancer (NSCLC)

Yongfu Wang, Yuanlin Wu, Shaoqiang Xie

Bioengineered. 2022; 13(2): 3651–3664. Published online 2022 Mar 1. doi: 10.1080/21655979.2021.2024321

PMCID:: PMC8973636

Abstract Article PDF–3.1M

Select item 88421659.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 862945010.

Prognostic Significance of Tripartite Motif Containing 16 Expression in Patients with Gastric Cancer

Jalil Afshar, Jamshid Mehrzad, Hassan Mehrad-Majd, Ladan Goshayeshi, Jafar Saeidi

Asian Pac J Cancer Prev. 2021 Aug; 22(8): 2445–2451. doi: 10.31557/APJCP.2021.22.8.2445

PMCID:: PMC8629450

Abstract Article PDF–374K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 784474512.

Downregulation of MicroRNA-135 Promotes Sensitivity of Non-Small Cell Lung Cancer to Gefitinib by Targeting TRIM16

Ning Wang, Tingting Zhang

Oncol Res. 2018; 26(7): 1005–1014. Published online 2018 Aug 23. doi: 10.3727/096504017X15144755633680

Retraction in:: Oncol Res. 2024; 32(11): 1813.

PMCID:: PMC7844745

Abstract Article

Select item 784110413.

Tripartite Motif 16 Inhibits the Migration and Invasion in Ovarian Cancer Cells

Hongwei Tan, Jin Qi, Guanghua Chu, Zhaoyang Liu

Oncol Res. 2017; 25(4): 551–558. Published online 2017 Apr 14. doi: 10.3727/096504016X14758370595285

PMCID:: PMC7841104

Abstract Article PDF–4.5M

Select item 768109314.

A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway

Qiangqiang Zheng, Haotian Shen, Zongrui Tong, Linxiang Cheng, Yuzi Xu, Zhiyun Feng, Shiyao Liao, Xiaojian Hu, Zongyou Pan, Zhengwei Mao, Yue Wang

Theranostics. 2021; 11(1): 147–163. Published online 2021 Jan 1. doi: 10.7150/thno.47723

Correction in:: Theranostics. 2024; 14(15): 5982–5983.

PMCID:: PMC7681093

Abstract Article PDF–3.2M

Select item 764586315.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 756688116.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 755035017.

AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation

Han Tian, Rong Lian, Yun Li, Chenying Liu, Shujun Liang, Wei Li, Tianyu Tao, Xingui Wu, Yaokai Ye, Xia Yang, Jian Han, Xuwei Chen, Jun Li, Yukai He, Mengfeng Li, Jueheng Wu, Junchao Cai

Nat Commun. 2020; 11: 5127. Published online 2020 Oct 12. doi: 10.1038/s41467-020-18929-0

PMCID:: PMC7550350

Abstract Article PDF–7.9M

Select item 613844218.

TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy

Kautilya Kumar Jena, Srinivasa Prasad Kolapalli, Subhash Mehto, Parej Nath, Biswajit Das, Pradyumna Kumar Sahoo, Abdul Ahad, Gulam Hussain Syed, Sunil K Raghav, Shantibhusan Senapati, Swati Chauhan, Santosh Chauhan

EMBO J. 2018 Sep 14; 37(18): e98358. Published online 2018 Aug 24. doi: 10.15252/embj.201798358

PMCID:: PMC6138442

Abstract Article PDF–4.3M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 521015420.

Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy

Tomonori Kimura, Jingyue Jia, Suresh Kumar, Seong Won Choi, Yuexi Gu, Michal Mudd, Nicolas Dupont, Shanya Jiang, Ryan Peters, Farzin Farzam, Ashish Jain, Keith A Lidke, Christopher M Adams, Terje Johansen, Vojo Deretic

EMBO J. 2017 Jan 4; 36(1): 42–60. Published online 2016 Dec 8. doi: 10.15252/embj.201695081

PMCID:: PMC5210154

Abstract Article PDF–3.7M

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