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Select item 112347371.

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy

Xiao Wang, Shuyan Wang, Xiaoyan Xu, Yuzhu Jiang, Liqin Ren, Haixia Zhang, Zhidan Li, Xianbing Liu, Xuemei Hu, Yushan Ren

Parasit Vectors. 2024; 17: 299. Published online 2024 Jul 10. doi: 10.1186/s13071-024-06379-2

PMCID:: PMC11234737

Abstract Article PDF–2.5M

Select item 110565062.

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9

Yingshu Luo, Zhenling Zhang, Jiangnan Ren, Chunxu Dou, Jiancheng Wen, Yang Yang, Xiaofeng Li, Zhixiang Yan, Yanzhi Han

Front Immunol. 2024; 15: 1303356. Published online 2024 Apr 15. doi: 10.3389/fimmu.2024.1303356

PMCID:: PMC11056506

Abstract Article PDF–7.0M

Select item 106631573.

The glucose transporter 2 regulates CD8⁺ T cell function via environment sensing

Hongmei Fu, Juho Vuononvirta, Silvia Fanti, Fabrizia Bonacina, Antonio D’Amati, Guosu Wang, Thanushiyan Poobalasingam, Maria Fankhaenel, Davide Lucchesi, Rachel Coleby, David Tarussio, Bernard Thorens, Robert J. Hearnden, M. Paula Longhi, Paul Grevitt, Madeeha H. Sheikh, Egle Solito, Susana A. Godinho, Michele Bombardieri, David M. Smith, Dianne Cooper, Asif J. Iqbal, Jeffrey C. Rathmell, Samuel Schaefer, Valle Morales, Katiuscia Bianchi, Giuseppe Danilo Norata, Federica M. Marelli-Berg

Nat Metab. 2023; 5(11): 1969–1985. Published online 2023 Oct 26. doi: 10.1038/s42255-023-00913-9

PMCID:: PMC10663157

Abstract Article PDF–9.6M

Select item 103617404.

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy

Linjing Li, Xuejie Xu, Xinxin Wang, Shuang Zhang, Wenkai Yao, Jiangqi Liu, Zhiqiang Liu, Pingchang Yang

Clin Exp Immunol. 2023 Aug; 213(2): 155–163. Published online 2023 Jun 4. doi: 10.1093/cei/uxad062

PMCID:: PMC10361740

Abstract Article PDF–2.5M

Select item 103250925.

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

Huntly M. Morrison, Julia Craft, Rafael Rivera-Lugo, Jeffery R. Johnson, Guillaume R. Golovkine, Samantha L. Bell, Claire E. Dodd, Erik Van Dis, Wandy L. Beatty, Shally R. Margolis, Teresa Repasy, Isaac Shaker, Angus Y. Lee, Russell E. Vance, Sarah A. Stanley, Robert O. Watson, Nevan J. Krogan, Daniel A. Portnoy, Bennett H. Penn, Jeffery S. Cox

PLoS Pathog. 2023 Jun; 19(6): e1011088. Published online 2023 Jun 23. doi: 10.1371/journal.ppat.1011088

PMCID:: PMC10325092

Abstract Article PDF–1.6M

Select item 100135386.

Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis

Congjuan Luo, Feng Luo, Lin Che, Hui Zhang, Long Zhao, Wei Zhang, Xiaofei Man, Quandong Bu, Hong Luan, Bin Zhou, Haiyan Zhou, Yan Xu

Ren Fail. 2023; 45(1): 2187229. Published online 2023 Mar 8. doi: 10.1080/0886022X.2023.2187229

PMCID:: PMC10013538

Abstract Article PDF–3.1M

Select item 97199497.

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson’s disease

Qinyu Peng, Guoxin Zhang, Xiaodi Guo, Lijun Dai, Min Xiong, Zhaohui Zhang, Liam Chen, Zhentao Zhang

Front Mol Neurosci. 2022; 15: 1046992. Published online 2022 Nov 21. doi: 10.3389/fnmol.2022.1046992

PMCID:: PMC9719949

Abstract Article PDF–12M

Select item 95344138.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 88944179.

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia

Miyoung Lee, Jamie A. G. Hamilton, Ganesh R. Talekar, Anthony J. Ross, Langston Michael, Manali Rupji, Bhakti Dwivedi, Sunil S. Raikar, Jeremy Boss, Christopher D. Scharer, Douglas K. Graham, Deborah DeRyckere, Christopher C. Porter, Curtis J. Henry

Nat Commun. 2022; 13: 1157. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28839-y

PMCID:: PMC8894417

Abstract Article PDF–2.7M

Select item 848455010.

Targeting the CD146/Galectin-9 axis protects the integrity of the blood–brain barrier in experimental cerebral malaria

Hongxia Duan, Shuai Zhao, Jianquan Xiang, Chenhui Ju, Xuehui Chen, Irene Gramaglia, Xiyun Yan

Cell Mol Immunol. 2021 Oct; 18(10): 2443–2454. Published online 2020 Nov 17. doi: 10.1038/s41423-020-00582-8

PMCID:: PMC8484550

Abstract Article PDF–4.4M

Select item 846309511.

Newly characterized decidual Tim-3⁺ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts

Xiaohui Hu, Qian Zhu, Yan Wang, Liling Wang, Zhihui Li, Gil Mor, Aihua Liao

Hum Reprod. 2020 Nov; 35(11): 2454–2466. Published online 2020 Oct 24. doi: 10.1093/humrep/deaa223

PMCID:: PMC8463095

Abstract Article PDF–1.0M

Select item 835259312.

Galectin-9 regulates the threshold of B cell activation and autoimmunity

Logan K Smith, Kareem Fawaz, Bebhinn Treanor

eLife. 2021; 10: e64557. Published online 2021 Aug 9. doi: 10.7554/eLife.64557

PMCID:: PMC8352593

Abstract Article PDF–4.9M

Select item 807328313.

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes

Mab P. Corrêa, Libnah L. Areias, Rebeca D. Correia-Silva, Solange C. G. P. D’Ávila, Andréia M. Leopoldino, Karin V. Greco, Cristiane D. Gil

Cells. 2021 Apr; 10(4): 947. Published online 2021 Apr 20. doi: 10.3390/cells10040947

PMCID:: PMC8073283

Abstract Article PDF–12M

Select item 796675714.

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2

Tomokazu Nunoue, Satoshi Yamaguchi, Sanae Teshigawara, Akihiro Katayama, Atsuko Nakatsuka, Jun Eguchi, Toshiro Niki, Jun Wada

Sci Rep. 2021; 11: 5991. Published online 2021 Mar 16. doi: 10.1038/s41598-021-85080-1

Correction in:: Sci Rep. 2021; 11: 18611.

PMCID:: PMC7966757

Abstract Article PDF–2.0M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 793335316.

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model

Valentin Baloche, Julie Rivière, Thi Bao Tram Tran, Aurore Gelin, Olivia Bawa, Nicolas Signolle, M′Boyba Khadija Diop, Philippe Dessen, Stéphanie Beq, Muriel David, Pierre Busson

Sci Rep. 2021; 11: 5227. Published online 2021 Mar 4. doi: 10.1038/s41598-021-84270-1

PMCID:: PMC7933353

Abstract Article PDF–14M

Select item 778549417.

AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system

Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R. Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic

Mol Cell. Author manuscript; available in PMC 2021 Mar 5.

Published in final edited form as: Mol Cell. 2020 Mar 5; 77(5): 951–969.e9. Published online 2020 Jan 28. doi: 10.1016/j.molcel.2019.12.028

PMCID:: PMC7785494

Abstract Article PDF–2.9M

Select item 764346718.

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice

Yiming Zhao, Xiang Li, Dingding Yu, Yonghao Hu, Wang Jin, Yafei Qin, Dejun Kong, Hongda Wang, Guangming Li, Alessandro Alessandrini, Hao Wang

Stem Cell Res Ther. 2020; 11: 471. Published online 2020 Nov 5. doi: 10.1186/s13287-020-01985-0

Correction in:: Stem Cell Res Ther. 2023; 14: 150.

PMCID:: PMC7643467

Abstract Article PDF–6.0M

Select item 745302319.

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas

Janaki N. Sudhakar, Hsueh-Han Lu, Hung-Yu Chiang, Ching-Shu Suen, Ming-Jing Hwang, Sung-Yu Wu, Chia-Ning Shen, Yao-Ming Chang, Fu-An Li, Fu-Tong Liu, Jr-Wen Shui

Nat Commun. 2020; 11: 4286. Published online 2020 Aug 27. doi: 10.1038/s41467-020-18102-7

PMCID:: PMC7453023

Abstract Article PDF–7.5M

Select item 741607320.

Galectin-9 Is a Novel Regulator of Epithelial Restitution

Brian S. Robinson, Bejan Saeedi, Connie M. Arthur, Josh Owens, Crystal Naudin, Nourine Ahmed, Liping Luo, Rheinallt Jones, Andrew Neish, Sean R. Stowell

Am J Pathol. 2020 Aug; 190(8): 1657–1666. doi: 10.1016/j.ajpath.2020.04.010

PMCID:: PMC7416073

Abstract Article PDF–3.7M

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