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Items: 1 to 20 of 44

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Disruption of Endosomal Sorting in Schwann Cells Leads to Defective Myelination and Endosomal Abnormalities Observed in Charcot-Marie-Tooth Disease
John W. McLean, Julie A. Wilson, Tina Tian, Jennifer A. Watson, Mary VanHart, Andrew J. Bean, Steven S. Scherer, David K. Crossman, Eroboghene Ubogu, Scott M. Wilson
J Neurosci. 2022 Jun 22; 42(25): 5085–5101. doi: 10.1523/JNEUROSCI.2481-21.2022
PMCID:
PMC9233440
AbstractArticlePDF–4.2M
4.
Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation
Veronica Birdsall, Konner Kirwan, Mei Zhu, Yuuta Imoto, Scott M Wilson, Shigeki Watanabe, Clarissa L Waites
Life Sci Alliance. 2022 Oct; 5(10): e202000745. Published online 2022 May 30. doi: 10.26508/lsa.202000745
PMCID:
PMC9152131
AbstractArticlePDF–3.7M
5.
Hgs Deficiency Caused Restrictive Cardiomyopathy via Disrupting Proteostasis
Zhenhua Li, Tianle Wang, Chong Xin, Yao Song, Jingyi Kong, Jingping Xu, Qiqi Liu, Yan Teng, Ning Hou, Xuan Cheng, Guan Yang, Wenjia Liu, Bin Zhou, Youyi Zhang, Xiao Yang, Jian Wang
Int J Biol Sci. 2022; 18(5): 2018–2031. Published online 2022 Feb 28. doi: 10.7150/ijbs.69024
PMCID:
PMC8935245
AbstractArticlePDF–2.3M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability
Zhenyang Yu, Jian Zeng, Jun Wang, Yaxiong Cui, Xiaopeng Song, Yizhe Zhang, Xuan Cheng, Ning Hou, Yan Teng, Yu Lan, Yeguang Chen, Xiao Yang
Cardiovasc Res. 2021 Feb 1; 117(2): 533–546. Published online 2020 Feb 11. doi: 10.1093/cvr/cvaa016
PMCID:
PMC7820882
AbstractArticlePDF–1.6M
8.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
9.
Hepatocyte Growth Factor-Met Signaling Is Required for Runx1 Extinction and Peptidergic Differentiation in Primary Nociceptive Neurons
Eduardo Gascon, Stéphane Gaillard, Pascale Malapert, Yang Liu, Lise Rodat-Despoix, Igor M. Samokhvalov, Patrick Delmas, Françoise Helmbacher, Flavio Maina, Aziz Moqrich
J Neurosci. 2010 Sep 15; 30(37): 12414–12423. doi: 10.1523/JNEUROSCI.3135-10.2010
PMCID:
PMC6633456
AbstractArticlePDF–2.3M
10.
Syk and Hrs Regulate TLR3-Mediated Antiviral Response in Murine Astrocytes
Matylda B. Mielcarska, Magdalena Bossowska-Nowicka, Karolina P. Gregorczyk-Zboroch, Zbigniew Wyżewski, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska, Felix N. Toka
Oxid Med Cell Longev. 2019; 2019: 6927380. Published online 2019 Apr 4. doi: 10.1155/2019/6927380
PMCID:
PMC6476135
AbstractArticlePDF–3.8M
11.
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon
eLife. 2018; 7: e32866. Published online 2018 Apr 20. doi: 10.7554/eLife.32866
PMCID:
PMC5927771
AbstractArticlePDF–9.1M
12.
The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization
Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber
Oncogene. Author manuscript; available in PMC 2017 Feb 14.
Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331
PMCID:
PMC5308218
AbstractArticlePDF–3.8M
13.
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways
Ryuji Oshima, Takafumi Hasegawa, Keiichi Tamai, Naoto Sugeno, Shun Yoshida, Junpei Kobayashi, Akio Kikuchi, Toru Baba, Akira Futatsugi, Ikuro Sato, Kennichi Satoh, Atsushi Takeda, Masashi Aoki, Nobuyuki Tanaka
Sci Rep. 2016; 6: 24997. Published online 2016 Apr 26. doi: 10.1038/srep24997
PMCID:
PMC4845015
AbstractArticlePDF–2.8M
14.
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS
Jennifer A. Watson, Bula J. Bhattacharyya, Jada H. Vaden, Julie A. Wilson, Mert Icyuz, Alan D. Howard, Edward Phillips, Tara M. DeSilva, Gene P. Siegal, Andrew J. Bean, Gwendalyn D. King, Scott E. Phillips, Richard J. Miller, Scott M. Wilson
PLoS Genet. 2015 Jun; 11(6): e1005290. Published online 2015 Jun 26. doi: 10.1371/journal.pgen.1005290
PMCID:
PMC4482608
AbstractArticlePDF–5.7M
15.
Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility
Jicheng Chen, Ning Hou, Chong Zhang, Yan Teng, Xuan Cheng, Zhenhua Li, Jie Ren, Jian Zeng, Rui Li, Wei Wang, Xiao Yang, Yu Lan
Int J Biol Sci. 2015; 11(7): 794–802. Published online 2015 May 22. doi: 10.7150/ijbs.12248
PMCID:
PMC4466460
AbstractArticlePDF–1.5M
16.
ESCRT-0 Protein Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate (Hrs) Is Targeted to Endosomes Independently of Signal-transducing Adaptor Molecule (STAM) and the Complex Formation with STAM Promotes Its Endosomal Dissociation
Katsuhiko Kojima, Yuji Amano, Kazuhisa Yoshino, Nobuyuki Tanaka, Kazuo Sugamura, Toshikazu Takeshita
J Biol Chem. 2014 Nov 28; 289(48): 33296–33310. Published online 2014 Oct 8. doi: 10.1074/jbc.M114.578245
Correction in:
J Biol Chem. 2015 Mar 27; 290(13): 8065–8066.
PMCID:
PMC4246087
AbstractArticlePDF–3.2M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of SMADs and TAK1 in early mouse embryo
Shigeto Miura, Yuji Mishina
Dev Dyn. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: Dev Dyn. 2011 Nov; 240(11): 2474–2481. Published online 2011 Sep 26. doi: 10.1002/dvdy.22750
PMCID:
PMC3197863
AbstractArticlePDF–1.5M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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