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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108219002.

Sexual dimorphism in melanocyte stem cell behavior reveals combinational therapeutic strategies for cutaneous repigmentation

Luye An, Dahihm Kim, Leanne R. Donahue, Menansili Abraham Mejooli, Chi-Yong Eom, Nozomi Nishimura, Andrew C. White

Nat Commun. 2024; 15: 796. Published online 2024 Jan 27. doi: 10.1038/s41467-024-45034-3

PMCID:: PMC10821900

Abstract Article PDF–6.3M

Select item 104914063.

β-Catenin transcriptional activity is required for establishment of inner pillar cell identity during cochlear development

Michael Ebeid, Ippei Kishimoto, Pooja Roy, Mohd Ali Abbas Zaidi, Alan G. Cheng, Sung-Ho Huh

PLoS Genet. 2023 Aug; 19(8): e1010925. Published online 2023 Aug 28. doi: 10.1371/journal.pgen.1010925

PMCID:: PMC10491406

Abstract Article PDF–3.9M

Select item 102344434.

Niche-mediated repair of airways is directed in an occupant-dependent manner

Handeng Lyu, Rachel Warren, Shan Gao, Kylie Klinkhammer, Tingting Yuan, Jin-San Zhang, Douglas Brownfield, Xiaokun Li, Stijn P. De Langhe

Cell Rep. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Cell Rep. 2022 Dec 20; 41(12): 111863. doi: 10.1016/j.celrep.2022.111863

PMCID:: PMC10234443

Abstract Article PDF–3.2M

Select item 100154145.

Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing

Laura Doherty, Matthew Wan, Anna Peterson, Daniel W. Youngstrom, Justin S. King, Ivo Kalajzic, Kurt D. Hankenson, Archana Sanjay

Bone. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Bone. 2023 Apr; 169: 116681. Published online 2023 Jan 25. doi: 10.1016/j.bone.2023.116681

PMCID:: PMC10015414

Abstract Article PDF–3.1M

Select item 99262666.

The Maresin 1–LGR6 axis decreases respiratory syncytial virus-induced lung inflammation

Nandini Krishnamoorthy, Katherine H. Walker, Thayse R. Brüggemann, Luciana P. Tavares, Ethan W. Smith, Julie Nijmeh, Yan Bai, Xingbin Ai, R. Elaine Cagnina, Melody G. Duvall, Jessica A. Lehoczky, Bruce D. Levy

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2206480120. Published online 2023 Jan 3. doi: 10.1073/pnas.2206480120

PMCID:: PMC9926266

Abstract Article PDF–1.6M

Select item 96645197.

LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice

Eline J. ter Steege, Thijmen Sijnesael, Lotte Enserink, Sjoerd Klarenbeek, Wisse E. Haakma, Elvira R.M. Bakker, Patrick W.B. Derksen

Neoplasia. 2023 Jan; 35: 100844. Published online 2022 Nov 10. doi: 10.1016/j.neo.2022.100844

PMCID:: PMC9664519

Abstract Article PDF–4.2M

Select item 94819758.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 90457229.

Mechanical tension mobilizes Lgr6⁺ epidermal stem cells to drive skin growth

Yingchao Xue, Chenyi Lyu, Ainsley Taylor, Amy Van Ee, Ashley Kiemen, YoungGeun Choi, Nima Khavanian, Dominic Henn, Chaewon Lee, Lisa Hwang, Eric Wier, Saifeng Wang, Sam Lee, Ang Li, Charles Kirby, Gaofeng Wang, Pei-Hsun Wu, Denis Wirtz, Luis A. Garza, Sashank K. Reddy

Sci Adv. 2022 Apr; 8(17): eabl8698. Published online 2022 Apr 27. doi: 10.1126/sciadv.abl8698

PMCID:: PMC9045722

Abstract Article PDF–4.0M

Select item 897709910.

Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts

Odemaris Narvaez del Pilar, Maria Jose Gacha Garay, Jichao Chen

Development. 2022 Mar 15; 149(6): dev200081. Published online 2022 Mar 18. doi: 10.1242/dev.200081

PMCID:: PMC8977099

Abstract Article

Select item 871667411.

Tumor Microenvironment-Derived R-spondins Enhance Anti-Tumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy

Yuting Tang, Qian Xu, Liang Hu, Xiaomei Yan, Xiaomin Feng, Asumi Yokota, Weinan Wang, Di Zhan, Durga Krishnamurthy, David E. Ochayon, Lijun Wen, Li Huo, Huimin Zeng, Yingwan Luo, L. Frank Huang, Mark Wunderlich, Jiwang Zhang, Eric Vivier, Jianfeng Zhou, Stephen N. Waggoner, Gang Huang

Cancer Discov. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Cancer Discov. 2021 Dec 1; 11(12): 3142–3157. doi: 10.1158/2159-8290.CD-20-0833

PMCID:: PMC8716674

Abstract Article PDF–2.5M

Select item 859716112.

LGR6 marks nephron progenitor cells

Ravian L. van Ineveld, Thanasis Margaritis, Berend A.P. Kooiman, Femke Groenveld, Hendrikus C.R. Ariese, Philip Lijnzaad, Hannah R. Johnson, Jeroen Korving, Ellen J. Wehrens, Frank Holstege, Jacco van Rheenen, Jarno Drost, Anne C. Rios, Frank L. Bos

Dev Dyn. 2021 Nov; 250(11): 1568–1583. Published online 2021 May 6. doi: 10.1002/dvdy.346

PMCID:: PMC8597161

Abstract Article PDF–99M

Select item 852817813.

Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization

Sixia Huang, Paola Kuri, Yann Aubert, Megan Brewster, Ning Li, Olivia Farrelly, Gabriella Rice, Hyunjin Bae, Stephen Prouty, Tzvete Dentchev, Wenqin Luo, Brian C. Capell, Panteleimon Rompolas

Cell Stem Cell. Author manuscript; available in PMC 2022 Sep 2.

Published in final edited form as: Cell Stem Cell. 2021 Sep 2; 28(9): 1582–1596.e6. Published online 2021 Jun 7. doi: 10.1016/j.stem.2021.05.007

PMCID:: PMC8528178

Abstract Article PDF–3.4M

Select item 825486714.

Laminin alpha 5 regulates mammary gland remodeling through luminal cell differentiation and Wnt4-mediated epithelial crosstalk

Johanna I. Englund, Alexandra Ritchie, Leander Blaas, Hanne Cojoc, Nalle Pentinmikko, Julia Döhla, Sharif Iqbal, Manuel Patarroyo, Pekka Katajisto

Development. 2021 Jun 15; 148(12): dev199281. Published online 2021 Jun 15. doi: 10.1242/dev.199281

PMCID:: PMC8254867

Abstract Article

Select item 811096815.

Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions

Ko Tsutsui, Hiroki Machida, Asako Nakagawa, Kyungmin Ahn, Ritsuko Morita, Kiyotoshi Sekiguchi, Jeffrey H. Miner, Hironobu Fujiwara

Nat Commun. 2021; 12: 2577. Published online 2021 May 10. doi: 10.1038/s41467-021-22881-y

PMCID:: PMC8110968

Abstract Article PDF–12M

Select item 761097416.

Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties

Giacomo Donati, Emanuel Rognoni, Toru Hiratsuka, Kifayathullah Liakath-Ali, Esther Hoste, Gozde Kar, Melis Kayikci, Roslin Russel, Kai Kretzschmar, Klaas Mulder, Sarah Teichmann, Fiona M. Watt

Nat Cell Biol. Author manuscript; available in PMC 2021 Jun 14.

Published in final edited form as: Nat Cell Biol. 2017 Jun 1; 19(6): 603–613. Published online 2017 May 15. doi: 10.1038/ncb3532

PMCID:: PMC7610974

Abstract Article PDF–4.3M

Select item 722876617.

R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors

Valerie PI Vidal, Fariba Jian-Motamedi, Samah Rekima, Elodie P Gregoire, Emmanuelle Szenker-Ravi, Marc Leushacke, Bruno Reversade, Marie-Christine Chaboissier, Andreas Schedl

eLife. 2020; 9: e53895. Published online 2020 May 1. doi: 10.7554/eLife.53895

PMCID:: PMC7228766

Abstract Article PDF–10M

Select item 722526918.

Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice

Yong-Ri Jin, Xiang Hua Han, Katsuhiko Nishimori, Dan Ben-Avraham, Youn Jeong Oh, Jae-won Shim, Jeong Kyo Yoon

Front Cell Dev Biol. 2020; 8: 264. Published online 2020 May 8. doi: 10.3389/fcell.2020.00264

PMCID:: PMC7225269

Abstract Article PDF–5.4M

Select item 707798519.

Coordinated hedgehog signaling induces new hair follicles in adult skin

Xiaoyan Sun, Alexandra Are, Karl Annusver, Unnikrishnan Sivan, Tina Jacob, Tim Dalessandri, Simon Joost, Anja Füllgrabe, Marco Gerling, Maria Kasper

eLife. 2020; 9: e46756. Published online 2020 Mar 17. doi: 10.7554/eLife.46756

PMCID:: PMC7077985

Abstract Article PDF–11M

Select item 687951820.

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

Ryo Seishima, Carly Leung, Swathi Yada, Katzrin Bte Ahmed Murad, Liang Thing Tan, Amin Hajamohideen, Si Hui Tan, Hideki Itoh, Kazuhiro Murakami, Yoshihiro Ishida, Satoshi Nakamizo, Yusuke Yoshikawa, Esther Wong, Nick Barker

Nat Commun. 2019; 10: 5378. Published online 2019 Nov 26. doi: 10.1038/s41467-019-13363-3

PMCID:: PMC6879518

Abstract Article PDF–6.8M

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