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Items: 1 to 20 of 103

1.
Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction
Luke A. Fournier, Rhushikesh A. Phadke, Maria Salgado, Alison Brack, Jian Carlo Nocon, Sonia Bolshakova, Jaylyn R. Grant, Nicole M. Padró Luna, Kamal Sen, Alberto Cruz-Martín
iScience. 2024 Sep 20; 27(9): 110800. Published online 2024 Aug 30. doi: 10.1016/j.isci.2024.110800
PMCID:
PMC11416532
AbstractArticlePDF–7.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes
Tatyana Veremeyko, Rongcai Jiang, Mingliang He, Eugene D. Ponomarev
Front Cell Neurosci. 2023; 17: 1170031. Published online 2023 May 10. doi: 10.3389/fncel.2023.1170031
PMCID:
PMC10206007
AbstractArticlePDF–5.6M
5.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
6.
Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice
Tian Zhou, Yuxin Li, Xiaoyu Li, Fanzhuo Zeng, Yanxia Rao, Yang He, Yafei Wang, Meizhen Liu, Dali Li, Zhen Xu, Xin Zhou, Siling Du, Fugui Niu, Jiyun Peng, Xifan Mei, Sheng-Jian Ji, Yousheng Shu, Wei Lu, Feifan Guo, Tianzhun Wu, Ti-Fei Yuan, Ying Mao, Bo Peng
Nat Commun. 2022; 13: 6233. Published online 2022 Oct 24. doi: 10.1038/s41467-022-33932-3
PMCID:
PMC9592609
AbstractArticlePDF–11M
7.
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice
Melis Yilmaz, Esra Yalcin, Jessy Presumey, Ernest Aw, Minghe Ma, Christopher W. Whelan, Beth Stevens, Steven A. McCarroll, Michael C. Carroll
Nat Neurosci. Author manuscript; available in PMC 2021 Apr 30.
Published in final edited form as: Nat Neurosci. 2021 Feb; 24(2): 214–224. Published online 2020 Dec 22. doi: 10.1038/s41593-020-00763-8
PMCID:
PMC8086435
AbstractArticlePDF–6.7M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Complement C4A Regulates Autoreactive B Cells in Murine Lupus
Léa Simoni, Jessy Presumey, Cees E. van der Poel, Carlos Castrillon, Sarah E. Chang, Paul J. Utz, Michael C. Carroll
Cell Rep. Author manuscript; available in PMC 2021 Mar 3.
Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108330. doi: 10.1016/j.celrep.2020.108330
PMCID:
PMC7927756
AbstractArticlePDF–2.4M
10.
Complement C4 Prevents Viral Infection through Capsid Inactivation
Maria Bottermann, Stian Foss, Sarah L. Caddy, Dean Clift, Laurens M. van Tienen, Marina Vaysburd, James Cruickshank, Kevin O’Connell, Jessica Clark, Keith Mayes, Katie Higginson, Heidrun E. Lode, Martin B. McAdam, Inger Sandlie, Jan Terje Andersen, Leo C. James
Cell Host Microbe. 2019 Apr 10; 25(4): 617–629.e7. doi: 10.1016/j.chom.2019.02.016
PMCID:
PMC6461443
AbstractArticle
11.
Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling
Chao Hu, Long Li, Peipei Ding, Ling Li, Xiaowen Ge, Long Zheng, Xuanchuan Wang, Jina Wang, Weitao Zhang, Na Wang, Hongyu Gu, Fan Zhong, Ming Xu, Ruiming Rong, Tongyu Zhu, Weiguo Hu
J Immunol. 2018 Dec 15; 201(12): 3717–3730. Published online 2018 Nov 14. doi: 10.4049/jimmunol.1800987
PMCID:
PMC6287101
AbstractArticlePDF–3.6M
12.
Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
Lisa E. Gralinski, Timothy P. Sheahan, Thomas E. Morrison, Vineet D. Menachery, Kara Jensen, Sarah R. Leist, Alan Whitmore, Mark T. Heise, Ralph S. Baric
mBio. 2018 Sep-Oct; 9(5): e01753-18. Published online 2018 Oct 9. doi: 10.1128/mBio.01753-18
PMCID:
PMC6178621
AbstractArticlePDF–3.6M
13.
Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy
Kenneth J. Katschke, Jr., Hongkang Xi, Christian Cox, Tom Truong, Yann Malato, Wyne P. Lee, Brent McKenzie, Rommel Arceo, Jianhua Tao, Linda Rangell, Mike Reichelt, Lauri Diehl, Justin Elstrott, Robby M Weimer, Menno van Lookeren Campagne
Sci Rep. 2018; 8: 7348. Published online 2018 May 9. doi: 10.1038/s41598-018-25557-8
Correction in:
Sci Rep. 2018; 8: 13055.
PMCID:
PMC5943270
AbstractArticlePDF–9.9M
14.
Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
Congcong Zhang, Chunxiao Wang, Yulin Li, Takashi Miwa, Chang Liu, Wei Cui, Wen-Chao Song, Jie Du
Nat Commun. 2017; 8: 2078. Published online 2017 Dec 12. doi: 10.1038/s41467-017-01526-z
PMCID:
PMC5727192
AbstractArticlePDF–4.6M
15.
Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival
Jennifer A. Caine, Yi-Pin Lin, Julie R. Kessler, Hiromi Sato, John M. Leong, Jenifer Coburn
Cell Microbiol. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Cell Microbiol. 2017 Dec; 19(12): 10.1111/cmi.12786. Published online 2017 Sep 26. doi: 10.1111/cmi.12786
Correction in:
Cell Microbiol. 2021 Jan; 23(1): e13286.
PMCID:
PMC5680108
AbstractArticlePDF–1.9M
16.
Complement Proteins C3 and C4 Bind to Collagen and Elastin in the Vascular Wall: A Potential Role in Vascular Stiffness and Atherosclerosis
Kelly J. Shields, Donna Stolz, Simon C. Watkins, Joseph M. Ahearn
Clin Transl Sci. 2011 Jun; 4(3): 146–152. Published online 2011 Jun 27. doi: 10.1111/j.1752-8062.2011.00304.x
PMCID:
PMC5439861
AbstractArticlePDF–1.4M
17.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
18.
Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection
Ajitanuj Rattan, Shailesh D. Pawar, Renuka Nawadkar, Neeraja Kulkarni, Girdhari Lal, Jayati Mullick, Arvind Sahu
PLoS Pathog. 2017 Mar; 13(3): e1006248. Published online 2017 Mar 16. doi: 10.1371/journal.ppat.1006248
PMCID:
PMC5354441
AbstractArticlePDF–4.0M
19.
Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4
Elham Asgari, Conrad A. Farrar, Nicholas Lynch, Youssif M. Ali, Silke Roscher, Cordula Stover, Wuding Zhou, Wilhelm J. Schwaeble, Steven H. Sacks
FASEB J. 2014 Sep; 28(9): 3996–4003. doi: 10.1096/fj.13-246306
PMCID:
PMC5184842
AbstractArticle
20.
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury
Conrad A. Farrar, David Tran, Ke Li, Weiju Wu, Qi Peng, Wilhelm Schwaeble, Wuding Zhou, Steven H. Sacks
J Clin Invest. 2016 May 2; 126(5): 1911–1925. Published online 2016 Apr 18. doi: 10.1172/JCI83000
PMCID:
PMC4855924
AbstractArticlePDF–7.2M

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