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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis
Jing Xu, Rongtian Guo, Nasi Wen, Luping Li, Yong Yi, Jingzhen Chen, Zongyu He, Jian Yang, Zhi-Xiong Jim Xiao, Mengmeng Niu
PLoS Biol. 2023 Dec; 21(12): e3002446. Published online 2023 Dec 22. doi: 10.1371/journal.pbio.3002446
PMCID:
PMC10745200
AbstractArticlePDF–3.2M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk
SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens
Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369
PMCID:
PMC7225129
AbstractArticle
5.
The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance
Sathish K. Murali, Takwa S. Aroankins, Hanne B. Moeller, Robert A. Fenton
Cells. 2019 Mar; 8(3): 265. Published online 2019 Mar 21. doi: 10.3390/cells8030265
PMCID:
PMC6468601
AbstractArticlePDF–2.1M
6.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
7.
Ubiquitination of Rheb governs growth factor-induced mTORC1 activation
Lu Deng, Lei Chen, Linlin Zhao, Yan Xu, Xiaoping Peng, Xinbo Wang, Lin Ding, Jiali Jin, Hongqi Teng, Yanming Wang, Weijuan Pan, Fei Yu, Lujian Liao, Li Li, Xin Ge, Ping Wang
Cell Res. 2019 Feb; 29(2): 136–150. Published online 2018 Dec 4. doi: 10.1038/s41422-018-0120-9
PMCID:
PMC6355928
AbstractArticlePDF–3.4M
8.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
9.
USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication
Chao Xu, Yang Peng, Qin Zhang, Xiao-Peng Xu, Xiang-Min Kong, Wei-Feng Shi
Sci Rep. 2018; 8: 13418. Published online 2018 Sep 7. doi: 10.1038/s41598-018-31734-6
Correction in:
Sci Rep. 2023; 13: 11670.
PMCID:
PMC6128947
AbstractArticlePDF–3.2M
10.
USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling
Fangfang Zhou, Feng Xie, Ke Jin, Zhengkui Zhang, Marcello Clerici, Rui Gao, Maarten van Dinther, Titia K Sixma, Huizhe Huang, Long Zhang, Peter ten Dijke
EMBO J. 2017 Jun 1; 36(11): 1623–1639. Published online 2017 May 3. doi: 10.15252/embj.201695372
PMCID:
PMC5452037
AbstractArticlePDF–5.6M
11.
Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling
Akhee S. Jahan, Maxime Lestra, Lee Kim Swee, Ying Fan, Mart M. Lamers, Fikadu G. Tafesse, Christopher S. Theile, Eric Spooner, Roberto Bruzzone, Hidde L. Ploegh, Sumana Sanyal
Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): E705–E714. Published online 2016 Jan 25. doi: 10.1073/pnas.1521763113
PMCID:
PMC4760780
AbstractArticlePDF–1.4M
12.
Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11
Caitlyn Vlasschaert, Xuhua Xia, Josée Coulombe, Douglas A. Gray
BMC Evol Biol. 2015; 15: 230. Published online 2015 Oct 26. doi: 10.1186/s12862-015-0511-1
PMCID:
PMC4624187
AbstractArticlePDF–3.0M
13.
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
Kifayathullah Liakath-Ali, Valerie E. Vancollie, Emma Heath, Damian P. Smedley, Jeanne Estabel, David Sunter, Tia DiTommaso, Jacqueline K. White, Ramiro Ramirez-Solis, Ian Smyth, Karen P. Steel, Fiona M. Watt
Nat Commun. 2014 Apr 11; 5: 3540. Published online 2014 Apr 11. doi: 10.1038/ncomms4540
PMCID:
PMC3996542
AbstractArticlePDF–4.0M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Ubiquitin-specific Protease 4 Mitigates Toll-like/Interleukin-1 Receptor Signaling and Regulates Innate Immune Activation
FangFang Zhou, Xiaofei Zhang, Hans van Dam, Peter ten Dijke, Huizhe Huang, Long Zhang
J Biol Chem. 2012 Mar 30; 287(14): 11002–11010. Published online 2012 Jan 19. doi: 10.1074/jbc.M111.328187
PMCID:
PMC3322833
AbstractArticlePDF–2.6M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1
Xinna Zhang, Franklin G Berger, Jianhua Yang, Xiongbin Lu
EMBO J. 2011 Jun 1; 30(11): 2177–2189. Published online 2011 Apr 26. doi: 10.1038/emboj.2011.125
PMCID:
PMC3117646
AbstractArticlePDF–1.2M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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