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Select item 115517471.

PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators

Yuexi Wang, Ullas Valiya Chembazhi, Danielle Yee, Sijie Chen, Jie Ji, Yujie Wang, Ka Lam Nguyen, PoChing Lin, Antonia Ratti, Rex A Hess, Huanyu Qiao, CheMyong Ko, Jing Yang, Auinash Kalsotra, Wenyan Mei

Nucleic Acids Res. 2024 Nov 11; 52(20): 12244–12261. Published online 2024 Oct 7. doi: 10.1093/nar/gkae862

PMCID:: PMC11551747

Abstract Article PDF–9.7M

Select item 113720442.

Suppression of PTBP1 in hippocampal astrocytes promotes neurogenesis and ameliorates recognition memory in mice with cerebral ischemia

Yusuke Fukui, Ryuta Morihara, Xinran Hu, Yumiko Nakano, Taijun Yunoki, Mami Takemoto, Koji Abe, Toru Yamashita

Sci Rep. 2024; 14: 20521. Published online 2024 Sep 3. doi: 10.1038/s41598-024-71212-w

PMCID:: PMC11372044

Abstract Article PDF–8.9M

Select item 111464363.

Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice

Elisa Monzón‐Casanova, Kirsty J. Bates, Christopher W. J. Smith, Martin Turner

Eur J Immunol. 2021 Sep; 51(9): 2266–2273. Published online 2021 Jul 26. doi: 10.1002/eji.202149257

PMCID:: PMC11146436

Abstract Article PDF–1.7M

Select item 107666294.

Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway

Lihui Xuan, Zheng Xu, Jinhua Luo, Yin Wang, Yuhui Yan, Can Qu, Zuozhong Xie, Magdalena Skonieczna, Ping-Kun Zhou, Ruixue Huang

Exp Mol Med. 2023 Dec; 55(12): 2596–2607. Published online 2023 Dec 1. doi: 10.1038/s12276-023-01129-3

PMCID:: PMC10766629

Abstract Article PDF–5.7M

Select item 107588855.

Circ-CCT2 Activates Wnt/β-catenin Signaling to Facilitate Hepatoblastoma Development by Stabilizing PTBP1 mRNA

Qin Zhu, Yu Hu, Wei Jiang, Zheng-Lin Ou, Yuan-Bing Yao, Hong-Yan Zai

Cell Mol Gastroenterol Hepatol. 2024; 17(2): 175–197. Published online 2023 Oct 20. doi: 10.1016/j.jcmgh.2023.10.004

PMCID:: PMC10758885

Abstract Article PDF–13M

Select item 105604316.

lncRNA Helf promotes hepatic inflammation and fibrosis by interacting with PTBP1 to facilitate PIK3R5 mRNA stabilization

Xiaohui Han, Beichen Guo, Sicong Zhao, Yehua Li, Jing Zhu, Yifan He, Jiajun Wang, Qingbin Yao, Shuai Shao, Lina Zheng, Zhemin Shi, Tao Han, Wei Hong, Kun Zhang

Cell Mol Biol Lett. 2023; 28: 77. Published online 2023 Oct 7. doi: 10.1186/s11658-023-00492-3

PMCID:: PMC10560431

Abstract Article PDF–8.5M

Select item 103078527.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 101922528.

Polypyrimidine tract binding protein 1 exacerbates cardiac fibrosis by regulating fatty acid‐binding protein 5

Zhen Chen, Chaoyong He, Zhen Gao, Yu Li, Qian He, Yiyan Wang, Chao Cai

ESC Heart Fail. 2023 Jun; 10(3): 1677–1688. Published online 2023 Feb 14. doi: 10.1002/ehf2.14318

PMCID:: PMC10192252

Abstract Article PDF–4.8M

Select item 100663799.

Endothelial deletion of PTBP1 disrupts ventricular chamber development

Hongyu Liu, Ran Duan, Xiaoyu He, Jincu Qi, Tianming Xing, Yahan Wu, Liping Zhou, Lingling Wang, Yujing Shao, Fulei Zhang, Huixing Zhou, Xingdong Gu, Bowen Lin, Yuanyuan Liu, Yan Wang, Yi Liu, Li Li, Dandan Liang, Yi-Han Chen

Nat Commun. 2023; 14: 1796. Published online 2023 Mar 31. doi: 10.1038/s41467-023-37409-9

PMCID:: PMC10066379

Abstract Article PDF–7.8M

Select item 1001836410.

PTBP1 controls intestinal epithelial regeneration through post-transcriptional regulation of gene expression

Ullas Valiya Chembazhi, Wesley S Tung, Hyojeong Hwang, Yuexi Wang, Aryan Lalwani, Ka Lam Nguyen, Sushant Bangru, Danielle Yee, Kristy Chin, Jing Yang, Auinash Kalsotra, Wenyan Mei

Nucleic Acids Res. 2023 Mar 21; 51(5): 2397–2414. Published online 2023 Feb 6. doi: 10.1093/nar/gkad042

PMCID:: PMC10018364

Abstract Article PDF–14M

Select item 961939611.

Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina

Thanh Hoang, Dong Won Kim, Haley Appel, Nicole A. Pannullo, Patrick Leavey, Manabu Ozawa, Sika Zheng, Minzhong Yu, Neal S. Peachey, Seth Blackshaw

Cell Rep. Author manuscript; available in PMC 2022 Oct 31.

Published in final edited form as: Cell Rep. 2022 Jun 14; 39(11): 110849. doi: 10.1016/j.celrep.2022.110849

PMCID:: PMC9619396

Abstract Article PDF–992K

Select item 954606112.

Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells

Vanessa D'Angeli, Elisa Monzón‐Casanova, Louise S. Matheson, Özge Gizlenci, Georg Petkau, Clare Gooding, Rebecca V. Berrens, Christopher W. J. Smith, Martin Turner

Eur J Immunol. 2022 Jul; 52(7): 1058–1068. Published online 2022 Apr 29. doi: 10.1002/eji.202149781

PMCID:: PMC9546061

Abstract Article PDF–1.4M

Select item 948193313.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 937138214.

Critical examination of Ptbp1-mediated glia-to-neuron conversion in the mouse retina

Ye Xie, Jing Zhou, Bo Chen

Cell Rep. Author manuscript; available in PMC 2022 Aug 11.

Published in final edited form as: Cell Rep. 2022 Jun 14; 39(11): 110960. doi: 10.1016/j.celrep.2022.110960

PMCID:: PMC9371382

Abstract Article PDF–2.3M

Select item 933534415.

Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions

Jessica A. Hensel, Sarah-Anne E. Nicholas, Amy L. Kimble, Arjun S. Nagpal, Omar M. F. Omar, Jordan D. Tyburski, Evan R. Jellison, Antoine Ménoret, Manabu Ozawa, Annabelle Rodriguez-Oquendo, Anthony T. Vella, Patrick A. Murphy

Proc Natl Acad Sci U S A. 2022 Jul 26; 119(30): e2122227119. Published online 2022 Jul 18. doi: 10.1073/pnas.2122227119

PMCID:: PMC9335344

Abstract Article PDF–3.0M

Select item 920875916.

Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease

Weizhao Chen, Qiongping Zheng, Qiaoying Huang, Shanshan Ma, Mingtao Li

eLife. 2022; 11: e75636. Published online 2022 May 10. doi: 10.7554/eLife.75636

PMCID:: PMC9208759

Abstract Article PDF–6.1M

Select item 913127717.

PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptor

Kankai Wang, Sishi Pan, Peiqi Zhao, Li Liu, Zhen Chen, Han Bao, Hao Wang, Ying Zhang, Qichuan Zhuge, Jianjing Yang

Theranostics. 2022; 12(8): 3847–3861. Published online 2022 May 9. doi: 10.7150/thno.71100

PMCID:: PMC9131277

Abstract Article PDF–9.6M

Select item 901455918.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 898952919.

EWS splicing regulation contributes to balancing Foxp1 isoforms required for neuronal differentiation

Veronica Verdile, Francesca Svetoni, Piergiorgio La Rosa, Gabriele Ferrante, Eleonora Cesari, Claudio Sette, Maria Paola Paronetto

Nucleic Acids Res. 2022 Apr 8; 50(6): 3362–3378. Published online 2022 Mar 7. doi: 10.1093/nar/gkac154

PMCID:: PMC8989529

Abstract Article PDF–5.5M

Select item 874218820.

LncRNA SNHG1 modulates adipogenic differentiation of BMSCs by promoting DNMT1 mediated Opg hypermethylation via interacting with PTBP1

Xiao Yu, Meng‐Sheng Song, Peng‐Ze Rong, Xian‐Jun Chen, Lin Shi, Cheng‐Hao Wang, Qing‐Jiang Pang

J Cell Mol Med. 2022 Jan; 26(1): 60–74. Published online 2021 Dec 2. doi: 10.1111/jcmm.16982

PMCID:: PMC8742188

Abstract Article PDF–3.2M

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