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Select item 108631611.

Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury

Liubing Chen, Hongyi Fang, Xiaoyun Li, Peiling Yu, Yu Guan, Cuicui Xiao, Zhizhao Deng, Ziqing Hei, Chaojin Chen, Chenfang Luo

Cell Commun Signal. 2024; 22: 121. Published online 2024 Feb 12. doi: 10.1186/s12964-023-01443-3

PMCID:: PMC10863161

Abstract Article PDF–2.7M

Select item 96791712.

NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice

Matthew J Jennings, Alexia Kagiava, Leen Vendredy, Emily L Spaulding, Marina Stavrou, Denisa Hathazi, Anika Grüneboom, Vicky De Winter, Burkhard Gess, Ulrike Schara, Oksana Pogoryelova, Hanns Lochmüller, Christoph H Borchers, Andreas Roos, Robert W Burgess, Vincent Timmerman, Kleopas A Kleopa, Rita Horvath

Brain. 2022 Nov; 145(11): 3999–4015. Published online 2022 Feb 11. doi: 10.1093/brain/awac055

PMCID:: PMC9679171

Abstract Article PDF–1.7M

Select item 85990113.

AAV9-mediated Schwann cell-targeted gene therapy rescues a model of demyelinating neuropathy

Alexia Kagiava, Christos Karaiskos, Jan Richter, Christina Tryfonos, Matthew J. Jennings, Amanda J. Heslegrave, Irene Sargiannidou, Marina Stavrou, Henrik Zetterberg, Mary M. Reilly, Christina Christodoulou, Rita Horvath, Kleopas A. Kleopa

Gene Ther. 2021; 28(10-11): 659–675. Published online 2021 Mar 10. doi: 10.1038/s41434-021-00250-0

PMCID:: PMC8599011

Abstract Article PDF–5.0M

Select item 85097234.

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice

Vlatka Paštar, Mirela Lozić, Nela Kelam, Natalija Filipović, Branka Bernard, Yu Katsuyama, Katarina Vukojević

Int J Mol Sci. 2021 Oct; 22(19): 10712. Published online 2021 Oct 2. doi: 10.3390/ijms221910712

PMCID:: PMC8509723

Abstract Article PDF–7.5M

Select item 73643325.

Crosstalk Between Connexin32 and Mitochondrial Apoptotic Signaling Pathway Plays a Pivotal Role in Renal Ischemia Reperfusion-Induced Acute Kidney Injury

Chaojin Chen, Weifeng Yao, Shan Wu, Shaoli Zhou, Mian Ge, Yu Gu, Xiang Li, Guihua Chen, Joseph A. Bellanti, Song Guo Zheng, Dongdong Yuan, Ziqing Hei

Antioxid Redox Signal. 2019 Apr 20; 30(12): 1521–1538. Published online 2019 Mar 11. doi: 10.1089/ars.2017.7375

PMCID:: PMC7364332

Abstract Article PDF–2.4M

Select item 72610846.

Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation

Jay Luther, Sanjoy Khan, Manish K. Gala, Dmitriy Kedrin, Gautham Sridharan, Russell P. Goodman, John J. Garber, Ricard Masia, Erik Diagacomo, Daniel Adams, Kevin R. King, Samuel Piaker, Hans-Christian Reinecker, Martin L. Yarmush, Josepmaria Argemi, Ramon Bataller, Jules L. Dienstag, Raymond T. Chung, Suraj J. Patel

Proc Natl Acad Sci U S A. 2020 May 26; 117(21): 11667–11673. Published online 2020 May 11. doi: 10.1073/pnas.1911870117

Correction in:: Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16704.

PMCID:: PMC7261084

Abstract Article PDF–1.7M

Select item 69767837.

Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48‐linked NADPH oxidase 4 polyubiquitination and degradation

Zhiquan Chen, Xiaohong Sun, Qiuhong Chen, Tian Lan, Kaipeng Huang, Haiming Xiao, Zeyuan Lin, Yan Yang, Peiqing Liu, Heqing Huang

Br J Pharmacol. 2020 Jan; 177(1): 145–160. Published online 2019 Dec 23. doi: 10.1111/bph.14853

PMCID:: PMC6976783

Abstract Article PDF–23M

Select item 67629188.

Global Ischemia-Induced Increases in the Gap Junctional Proteins Connexin 32 (Cx32) and Cx36 in Hippocampus and Enhanced Vulnerability of Cx32 Knock-Out Mice

Keiji Oguro, Teresa Jover, Hidenobu Tanaka, Ying Lin, Takashi Kojima, Noriko Oguro, Sonja Y. Grooms, Michael V. L. Bennett, R. Suzanne Zukin

J Neurosci. 2001 Oct 1; 21(19): 7534–7542. doi: 10.1523/JNEUROSCI.21-19-07534.2001

PMCID:: PMC6762918

Abstract Article PDF–748K

Select item 67581619.

Connexin29 Is Uniquely Distributed within Myelinating Glial Cells of the Central and Peripheral Nervous Systems

Bruce M. Altevogt, Kleopas A. Kleopa, Friso R. Postma, Steven S. Scherer, David L. Paul

J Neurosci. 2002 Aug 1; 22(15): 6458–6470. doi: 10.1523/JNEUROSCI.22-15-06458.2002

PMCID:: PMC6758161

Abstract Article PDF–1.5M

Select item 674198510.

Oligodendrocyte Progenitor Enrichment in the Connexin32 Null-Mutant Mouse

Lysanne Melanson-Drapeau, Sandy Beyko, Shefali Davé, Andrea L. O. Hebb, Doug J. Franks, Caterina Sellitto, David L. Paul, Steffany A. L. Bennett

J Neurosci. 2003 Mar 1; 23(5): 1759–1768. doi: 10.1523/JNEUROSCI.23-05-01759.2003

PMCID:: PMC6741985

Abstract Article PDF–1.1M

Select item 674126711.

Connexins Are Critical for Normal Myelination in the CNS

Daniela M. Menichella, Daniel A. Goodenough, Erich Sirkowski, Steven S. Scherer, David L. Paul

J Neurosci. 2003 Jul 2; 23(13): 5963–5973. doi: 10.1523/JNEUROSCI.23-13-05963.2003

PMCID:: PMC6741267

Abstract Article PDF–1.3M

Select item 674081612.

Connexin 47 (Cx47)-Deficient Mice with Enhanced Green Fluorescent Protein Reporter Gene Reveal Predominant Oligodendrocytic Expression of Cx47 and Display Vacuolized Myelin in the CNS

Benjamin Odermatt, Kerstin Wellershaus, Anke Wallraff, Gerald Seifert, Joachim Degen, Carsten Euwens, Babette Fuss, Heinrich Büssow, Karl Schilling, Christian Steinhäuser, Klaus Willecke

J Neurosci. 2003 Jun 1; 23(11): 4549–4559. doi: 10.1523/JNEUROSCI.23-11-04549.2003

PMCID:: PMC6740816

Abstract Article PDF–1.0M

Select item 672599213.

Transgenic Expression of Human Connexin32 in Myelinating Schwann Cells Prevents Demyelination in Connexin32-Null Mice

Steven S. Scherer, Yi-Tian Xu, Albee Messing, Klaus Willecke, Kenneth H. Fischbeck, Linda Jo Bone Jeng

J Neurosci. 2005 Feb 9; 25(6): 1550–1559. doi: 10.1523/JNEUROSCI.3082-04.2005

PMCID:: PMC6725992

Abstract Article PDF–824K

Select item 672524114.

Prenylation-Defective Human Connexin32 Mutants Are Normally Localized and Function Equivalently to Wild-Type Connexin32 in Myelinating Schwann Cells

Yan Huang, Erich E. Sirkowski, John T. Stickney, Steven S. Scherer

J Neurosci. 2005 Aug 3; 25(31): 7111–7120. doi: 10.1523/JNEUROSCI.1319-05.2005

PMCID:: PMC6725241

Abstract Article PDF–539K

Select item 667491915.

Connexin29 Is Highly Expressed in Cochlear Schwann Cells, and It Is Required for the Normal Development and Function of the Auditory Nerve of Mice

Wenxue Tang, Yanping Zhang, Qing Chang, Shoab Ahmad, Ian Dahlke, Hong Yi, Ping Chen, David L. Paul, Xi Lin

J Neurosci. 2006 Feb 15; 26(7): 1991–1999. doi: 10.1523/JNEUROSCI.5055-05.2006

PMCID:: PMC6674919

Abstract Article PDF–690K

Select item 667464716.

Genetic and Physiological Evidence That Oligodendrocyte Gap Junctions Contribute to Spatial Buffering of Potassium Released during Neuronal Activity

Daniela M. Menichella, Marta Majdan, Rajeshwar Awatramani, Daniel A. Goodenough, Erich Sirkowski, Steven S. Scherer, David L. Paul

J Neurosci. 2006 Oct 25; 26(43): 10984–10991. doi: 10.1523/JNEUROSCI.0304-06.2006

Correction in:: J Neurosci. 2006 Nov 29; 26(48): np.

PMCID:: PMC6674647

Abstract Article PDF–803K

Select item 661897017.

Connexin47 Protein Phosphorylation and Stability in Oligodendrocytes Depend on Expression of Connexin43 Protein in Astrocytes

Dennis May, Oliver Tress, Gerald Seifert, Klaus Willecke

J Neurosci. 2013 May 1; 33(18): 7985–7996. doi: 10.1523/JNEUROSCI.5874-12.2013

PMCID:: PMC6618970

Abstract Article PDF–7.1M

Select item 657334318.

Structural Abnormalities and Deficient Maintenance of Peripheral Nerve Myelin in Mice Lacking the Gap Junction Protein Connexin 32

Patrizia Anzini, Dirk H.-H. Neuberg, Melitta Schachner, Eric Nelles, Klaus Willecke, Jürgen Zielasek, Klaus V. Toyka, Ueli Suter, Rudolf Martini

J Neurosci. 1997 Jun 15; 17(12): 4545–4551. doi: 10.1523/JNEUROSCI.17-12-04545.1997

PMCID:: PMC6573343

Abstract Article PDF–719K

Select item 657070619.

Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes

Juan F. Reyes, Christopher Sackmann, Alana Hoffmann, Per Svenningsson, Jürgen Winkler, Martin Ingelsson, Martin Hallbeck

Acta Neuropathol. 2019; 138(1): 23–47. Published online 2019 Apr 11. doi: 10.1007/s00401-019-02007-x

PMCID:: PMC6570706

Abstract Article PDF–13M

Select item 651921220.

Regulatory role of oligodendrocyte gap junctions in inflammatory demyelination

Christos P. Papaneophytou, Elena Georgiou, Christos Karaiskos, Irene Sargiannidou, Kyriaki Markoullis, Mona M. Freidin, Charles K. Abrams, Kleopas A. Kleopa

Glia. 2018 Dec; 66(12): 2589–2603. Published online 2018 Oct 16. doi: 10.1002/glia.23513

PMCID:: PMC6519212

Abstract Article PDF–11M

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