PMC Links for GEO Profiles (Select 123398468) - PMC

Select item 104998211.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 80090482.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 76118063.

Clinical characteristics, molecular features and long-term follow up of 15 patients with neonatal diabetes: a single center experience

Zehra Yavas Abali, Elisa De Franco, Esin Karakilic Ozturan, Sukran Poyrazoglu, Ruveyde Bundak, Firdevs Bas, Sarah E Flanagan, Feyza Darendeliler

Horm Res Paediatr. Author manuscript; available in PMC 2021 Oct 12.

Published in final edited form as: Horm Res Paediatr. 2020 Jan 1; 93(7-8): 423–432. Published online 2021 Jan 26. doi: 10.1159/000512247

PMCID:: PMC7611806

Abstract Article PDF–658K

Select item 75267314.

Clinical Characteristics and Long-term Follow-up of Patients with Diabetes Due To PTF1A Enhancer Mutations

Huseyin Demirbilek, Atilla Cayir, Sarah E Flanagan, Ruken Yıldırım, Yılmaz Kor, Fatih Gurbuz, Belma Haliloğlu, Melek Yıldız, Rıza Taner Baran, Emine Demet Akbas, Meliha Demiral, Edip Ünal, Gulcin Arslan, Dogus Vuralli, Gonul Buyukyilmaz, Sara Al-Khawaga, Amira Saeed, Maryam Al Maadheed, Amel Khalifa, Hasan Onal, Bilgin Yuksel, Mehmet Nuri Ozbek, Abdullah Bereket, Andrew T Hattersley, Khalid Hussain, Elisa De Franco

J Clin Endocrinol Metab. 2020 Dec; 105(12): e4351–e4359. Published online 2020 Sep 7. doi: 10.1210/clinem/dgaa613

PMCID:: PMC7526731

Abstract Article

Select item 66728575.

Origin of Climbing Fiber Neurons and Their Developmental Dependence on Ptf1a

Mayumi Yamada, Mami Terao, Toshio Terashima, Tomoyuki Fujiyama, Yoshiya Kawaguchi, Yo-ichi Nabeshima, Mikio Hoshino

J Neurosci. 2007 Oct 10; 27(41): 10924–10934. doi: 10.1523/JNEUROSCI.1423-07.2007

PMCID:: PMC6672857

Abstract Article PDF–877K

Select item 60546496.

Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a

Dongchang Xiao, Xiaoning Liu, Min Zhang, Min Zou, Qinqin Deng, Dayu Sun, Xuting Bian, Yulong Cai, Yanan Guo, Shuting Liu, Shengguo Li, Evelyn Shiang, Hongyu Zhong, Lin Cheng, Haiwei Xu, Kangxin Jin, Mengqing Xiang

Nat Commun. 2018; 9: 2865. Published online 2018 Jul 20. doi: 10.1038/s41467-018-05209-1

PMCID:: PMC6054649

Abstract Article PDF–9.2M

Select item 51262917.

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A

Chinh Q. Hoang, Michael A. Hale, Ana C. Azevedo-Pouly, Hans P. Elsässer, Tye G. Deering, Spencer G. Willet, Fong C. Pan, Mark A. Magnuson, Christopher V. E. Wright, Galvin H. Swift, Raymond J. MacDonald

Mol Cell Biol. 2016 Dec 15; 36(24): 3033–3047. Prepublished online 2016 Oct 3. Published online 2016 Nov 28. doi: 10.1128/MCB.00358-16

PMCID:: PMC5126291

Abstract Article PDF–7.3M

Select item 50011728.

Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation

Jayne A.L. Houghton, Galvin H. Swift, Charles Shaw-Smith, Sarah E. Flanagan, Elisa de Franco, Richard Caswell, Khalid Hussain, Sarar Mohamed, Majedah Abdulrasoul, Andrew T. Hattersley, Raymond J. MacDonald, Sian Ellard

Diabetes. 2016 Sep; 65(9): 2810–2815. Published online 2016 Jun 9. doi: 10.2337/db15-1666

PMCID:: PMC5001172

Abstract Article PDF–794K

Select item 48792139.

Loss of Ptf1a Leads to a Widespread Cell-Fate Misspecification in the Brainstem, Affecting the Development of Somatosensory and Viscerosensory Nuclei

Igor Y. Iskusnykh, Ekaterina Y. Steshina, Victor V. Chizhikov

J Neurosci. 2016 Mar 2; 36(9): 2691–2710. doi: 10.1523/JNEUROSCI.2526-15.2016

PMCID:: PMC4879213

Abstract Article PDF–14M

Select item 453674710.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

Nathan M Krah, Jean-Paul De La O, Galvin H Swift, Chinh Q Hoang, Spencer G Willet, Fong Chen Pan, Gabriela M Cash, Mary P Bronner, Christopher VE Wright, Raymond J MacDonald, L Charles Murtaugh

eLife. 2015; 4: e07125. Published online 2015 Jul 7. doi: 10.7554/eLife.07125

PMCID:: PMC4536747

Abstract Article PDF–7.4M

Select item 427124211.

The E3 Ubiquitin Ligase Thyroid Hormone Receptor-interacting Protein 12 Targets Pancreas Transcription Factor 1a for Proteasomal Degradation

Naïma Hanoun, Samuel Fritsch, Odile Gayet, Véronique Gigoux, Pierre Cordelier, Nelson Dusetti, Jérôme Torrisani, Marlène Dufresne

J Biol Chem. 2014 Dec 19; 289(51): 35593–35604. Published online 2014 Oct 29. doi: 10.1074/jbc.M114.620104

PMCID:: PMC4271242

Abstract Article PDF–1.6M

Select item 413175312.

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis

Michael N. Weedon, Ines Cebola, Ann-Marie Patch, Sarah E. Flanagan, Elisa De Franco, Richard Caswell, Santiago A. Rodríguez-Seguí, Charles Shaw-Smith, Candy H-H. Cho, Hana Lango Allen, Jayne AL. Houghton, Christian L. Roth, Rongrong Chen, Khalid Hussain, Phil Marsh, Ludovic Vallier, Anna Murray, International Pancreatic Agenesis Consortium, Sian Ellard, Jorge Ferrer, Andrew T. Hattersley

Nat Genet. Author manuscript; available in PMC 2014 Aug 13.

Published in final edited form as: Nat Genet. 2014 Jan; 46(1): 61–64. Published online 2013 Nov 10. doi: 10.1038/ng.2826