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Select item 115201011.

SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis

Laura Gebetsberger, Zahra Malekshahi, Aron Teutsch, Gabor Tajti, Frédéric Fontaine, Nara Marella, André Mueller, Lena Prantl, Hannes Stockinger, Heribert Stoiber, Anna Ohradanova-Repic

Emerg Microbes Infect. 2024; 13(1): 2417868. Published online 2024 Oct 22. doi: 10.1080/22221751.2024.2417868

PMCID:: PMC11520101

Abstract Article PDF–1.3M

Select item 111996862.

Complement-Coagulation Cross-talk: Factor H-mediated regulation of the Complement Classical Pathway activation by fibrin clots

Yu-Hoi Kang, Praveen M. Varghese, Ahmad Al Aiyan, Kirsten Pondman, Uday Kishore, Robert B. Sim

Front Immunol. 2024; 15: 1368852. Published online 2024 Jun 12. doi: 10.3389/fimmu.2024.1368852

PMCID:: PMC11199686

Abstract Article PDF–3.2M

Select item 109202953.

Protective role of complement factor H against the development of preeclampsia

Hadida Yasmin, Chiara Agostinis, Miriam Toffoli, Tamali Roy, Silvia Pegoraro, Andrea Balduit, Gabriella Zito, Nicoletta Di Simone, Giuseppe Ricci, Taruna Madan, Uday Kishore, Roberta Bulla

Front Immunol. 2024; 15: 1351898. Published online 2024 Feb 23. doi: 10.3389/fimmu.2024.1351898

PMCID:: PMC10920295

Abstract Article PDF–3.2M

Select item 108856194.

Gliosis-dependent expression of complement factor H truncated variants attenuates retinal neurodegeneration following ischemic injury

Josef Biber, Yassin Jabri, Sarah Glänzer, Aaron Dort, Patricia Hoffelner, Christoph Q. Schmidt, Oliver Bludau, Diana Pauly, Antje Grosche

J Neuroinflammation. 2024; 21: 56. Published online 2024 Feb 22. doi: 10.1186/s12974-024-03045-3

PMCID:: PMC10885619

Abstract Article PDF–13M

Select item 107674055.

Association of KDR (rs2071559, rs1870377), CFH (rs1061170, rs1410996) genes variants and serum levels with pituitary adenoma

Akvile Bruzaite, Greta Gedvilaite, Loresa Kriauciuniene, Rasa Liutkeviciene

Mol Genet Genomic Med. 2024 Jan; 12(1): e2289. Published online 2023 Oct 6. doi: 10.1002/mgg3.2289

PMCID:: PMC10767405

Abstract Article PDF–893K

Select item 107239086.

Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy

Yuqi Kang, Boyang Xu, Sufang Shi, Xujie Zhou, Pei Chen, Lijun Liu, Yebei Li, Yueqi Leng, Jicheng Lv, Li Zhu, Hong Zhang

Clin J Am Soc Nephrol. 2023 Dec; 18(12): 1583–1591. Published online 2023 Aug 31. doi: 10.2215/CJN.0000000000000290

PMCID:: PMC10723908

Abstract Article

Select item 106683937.

Complement factor H attenuates TNF-α-induced inflammation by upregulating EIF3C in rheumatoid arthritis

Yimeng Jia, Bin Feng, Xin Ji, Xinping Tian, Lidan Zhao, Jiaxin Zhou, Wen Zhang, Mengtao Li, Yunyun Fei, Xunyao Wu

J Transl Med. 2023; 21: 846. Published online 2023 Nov 23. doi: 10.1186/s12967-023-04730-2

PMCID:: PMC10668393

Abstract Article PDF–1.8M

Select item 105925618.

Identification of complement factor H variants that predispose to preeclampsia: a genetic and functional study

AI Lokki, Z Ren, M Triebwasser, E Daly, FINNPEC, M Perola, K Auro, R Burwick, JE Salmon, M Daly, H Laivuori, JP Atkinson, A Java, S Meri

BJOG. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: BJOG. 2023 Nov; 130(12): 1473–1482. Published online 2023 May 8. doi: 10.1111/1471-0528.17529

PMCID:: PMC10592561

Abstract Article PDF–776K

Select item 103280779.

Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation

Larisa Chernyaeva, Giorgio Ratti, Laura Teirilä, Satoshi Fudo, Uni Rankka, Anssi Pelkonen, Paula Korhonen, Katarzyna Leskinen, Salla Keskitalo, Kari Salokas, Christina Gkolfinopoulou, Katrina E Crompton, Matti Javanainen, Lotta Happonen, Markku Varjosalo, Tarja Malm, Ville Leinonen, Angeliki Chroni, Päivi Saavalainen, Seppo Meri, Tommi Kajander, Adam JM Wollman, Eija Nissilä, Karita Haapasalo

EMBO Rep. 2023 Jul; 24(7): e56467. Published online 2023 May 8. doi: 10.15252/embr.202256467

PMCID:: PMC10328077

Abstract Article PDF–12M

Select item 1020895210.

CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome

Yuka Sugawara, Hideki Kato, Masao Nagasaki, Yoko Yoshida, Madoka Fujisawa, Naoko Minegishi, Masayuki Yamamoto, Masaomi Nangaku

J Hum Genet. 2023; 68(6): 427–430. Published online 2023 Feb 9. doi: 10.1038/s10038-023-01129-1

PMCID:: PMC10208952

Abstract Article PDF–1.6M

Select item 1008433311.

Common complement factor H polymorphisms are linked with periodontitis in elderly patients

Aino Salminen, Milla Pietiäinen, Susanna Paju, Timo Sorsa, Päivi Mäntylä, Kåre Buhlin, Juha Sinisalo, Pirkko J. Pussinen

J Periodontol. 2022 Nov; 93(11): 1626–1634. Published online 2022 May 4. doi: 10.1002/JPER.22-0005

PMCID:: PMC10084333

Abstract Article PDF–549K

Select item 1003951112.

Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology

Yanting Su, Yuanyuan Guo, Jieyu Guo, Ting Zeng, Ting Wang, Wu Liu

BMC Genomics. 2023; 24: 146. Published online 2023 Mar 24. doi: 10.1186/s12864-023-09238-z

PMCID:: PMC10039511

Abstract Article PDF–2.0M

Select item 992323213.

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome

Rossella Piras, Elisabetta Valoti, Marta Alberti, Elena Bresin, Caterina Mele, Matteo Breno, Lucia Liguori, Roberta Donadelli, Miriam Rigoldi, Ariela Benigni, Giuseppe Remuzzi, Marina Noris

Front Immunol. 2022; 13: 1011580. Published online 2023 Jan 30. doi: 10.3389/fimmu.2022.1011580

PMCID:: PMC9923232

Abstract Article PDF–8.0M

Select item 991969114.

Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness

Beau J. Fenner, Hengtong Li, Alfred T. L. Gan, Young Seok Song, Yih Chung Tham, Jost B. Jonas, Ya Xing Wang, Ching Yu Cheng, Tien Yin Wong, Kelvin Y. C. Teo, Anna C. S. Tan, Qiao Fan, Chui Ming Gemmy Cheung

Invest Ophthalmol Vis Sci. 2023 Feb; 64(2): 10. Published online 2023 Feb 7. doi: 10.1167/iovs.64.2.10

Correction in:: Invest Ophthalmol Vis Sci. 2023 Mar; 64(3): 33.

PMCID:: PMC9919691

Abstract Article PDF–1.2M

Select item 983238815.

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration

Thomas M. Hallam, Thomas E. Cox, Kate Smith-Jackson, Vicky Brocklebank, April J. Baral, Nikolaos Tzoumas, David H. Steel, Edwin K. S. Wong, Victoria G. Shuttleworth, Andrew J. Lotery, Claire L. Harris, Kevin J. Marchbank, David Kavanagh

Front Immunol. 2022; 13: 1028760. Published online 2022 Dec 28. doi: 10.3389/fimmu.2022.1028760

PMCID:: PMC9832388

Abstract Article PDF–3.5M

Select item 971623216.

An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration

Robyn M. Biggs, Elisavet Makou, Scott Lauder, Andrew P. Herbert, Paul N. Barlow, Suresh K. Katti

Invest Ophthalmol Vis Sci. 2022 Nov; 63(12): 30. Published online 2022 Nov 29. doi: 10.1167/iovs.63.12.30

PMCID:: PMC9716232

Abstract Article PDF–1.9M

Select item 953977017.

Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis

Heba R. Gouda, Iman M. Talaat, Amal Bouzid, Hoda El-Assi, Amira Nabil, Thenmozhi Venkatachalam, Poorna Manasa Bhamidimarri, Inken Wohlers, Amena Mahdami, Saba EL-Gendi, Ahmed ElKoraie, Hauke Busch, Maha Saber-Ayad, Rifat Hamoudi, Nahed Baddour

Front Immunol. 2022; 13: 960068. Published online 2022 Sep 23. doi: 10.3389/fimmu.2022.960068

PMCID:: PMC9539770

Abstract Article PDF–2.0M

Select item 936367818.

Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish

Andrea R. Waksmunski, Kristy Miskimen, Yeunjoo E. Song, Michelle Grunin, Renee Laux, Denise Fuzzell, Sarada Fuzzell, Larry D. Adams, Laura Caywood, Michael Prough, Dwight Stambolian, William K. Scott, Margaret A. Pericak-Vance, Jonathan L. Haines

Invest Ophthalmol Vis Sci. 2022 Aug; 63(9): 8. Published online 2022 Aug 5. doi: 10.1167/iovs.63.9.8

PMCID:: PMC9363678

Abstract Article PDF–2.1M

Select item 936367419.

Phenotypic Expression of CFH Rare Variants in Age-Related Macular Degeneration Patients in the Coimbra Eye Study

Cláudia Farinha, Patrícia Barreto, Rita Coimbra, Adela Iutis, Maria Luz Cachulo, José Cunha-Vaz, Yara T. E. Lechanteur, Carel B. Hoyng, Rufino Silva

Invest Ophthalmol Vis Sci. 2022 Aug; 63(9): 5. Published online 2022 Aug 4. doi: 10.1167/iovs.63.9.5

PMCID:: PMC9363674

Abstract Article PDF–1.4M

Select item 934857620.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

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