PMC Links for GEO Profiles (Select 124231446) - PMC

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88646956.

Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications

Antonieta L. Salguero, Maggie Chen, Aaron T. Balana, Nam Chu, Hanjie Jiang, Brad A. Palanski, Hwan Bae, Katharine M. Wright, Sara Nathan, Heng Zhu, Sandra B. Gabelli, Matthew R. Pratt, Philip A. Cole

ACS Chem Biol. Author manuscript; available in PMC 2022 Feb 23.

Published in final edited form as: ACS Chem Biol. 2022 Jan 21; 17(1): 68–76. Published online 2021 Dec 23. doi: 10.1021/acschembio.1c00632

PMCID:: PMC8864695

Abstract Article PDF–1.1M

Select item 86053727.

Determining folding and binding properties of the C‐terminal SH2 domain of SHP2

Caterina Nardella, Francesca Malagrinò, Livia Pagano, Serena Rinaldo, Stefano Gianni, Angelo Toto

Protein Sci. 2021 Dec; 30(12): 2385–2395. Published online 2021 Oct 9. doi: 10.1002/pro.4201

PMCID:: PMC8605372

Abstract Article PDF–2.5M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81476999.

Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction

Vijay Kondreddy, Jhansi Magisetty, Shiva Keshava, L. Vijaya Mohan Rao, Usha R. Pendurthi

Arterioscler Thromb Vasc Biol. 2021 Jun; 41(6): 1987–2005. Published online 2021 Apr 8. doi: 10.1161/ATVBAHA.121.316153

PMCID:: PMC8147699

Abstract Article PDF–4.9M

Select item 769516710.

Targeting the Interaction between the SH3 Domain of Grb2 and Gab2

Francesca Malagrinò, Antonio Coluccia, Marianna Bufano, Giuseppe La Regina, Michela Puxeddu, Angelo Toto, Lorenzo Visconti, Alessio Paone, Maria Chiara Magnifico, Francesca Troilo, Francesca Cutruzzolà, Romano Silvestri, Stefano Gianni

Cells. 2020 Nov; 9(11): 2435. Published online 2020 Nov 7. doi: 10.3390/cells9112435

PMCID:: PMC7695167

Abstract Article PDF–1.8M

Select item 755116611.

MicroRNA-218 inhibits tumor angiogenesis of human renal cell carcinoma by targeting GAB2

Lijun Mu, Bing Guan, Juanhua Tian, Xiang Li, Qingzhi Long, Meiyu Wang, Wen Wang, Junjun She, Xudong Li, Dapeng Wu, Yuefeng Du

Oncol Rep. 2020 Nov; 44(5): 1961–1970. Published online 2020 Sep 8. doi: 10.3892/or.2020.7759

Correction in:: Oncol Rep. 2022 Nov; 48(5): 191.

PMCID:: PMC7551166

Abstract Article PDF–1.4M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 698120613.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 679415814.

LZTR1 is a regulator of RAS ubiquitination and signaling

Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga

Science. Author manuscript; available in PMC 2019 Oct 15.

Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210

PMCID:: PMC6794158

Abstract Article PDF–1.9M

Select item 676265115.

Nerve Growth Factor Activates Persistent Rap1 Signaling in Endosomes

Chengbiao Wu, Chun-Fai Lai, William C. Mobley

J Neurosci. 2001 Aug 1; 21(15): 5406–5416. doi: 10.1523/JNEUROSCI.21-15-05406.2001

PMCID:: PMC6762651

Abstract Article PDF–1.2M

Select item 674264616.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 654769417.

Mapping the allosteric network within a SH3 domain

Francesca Malagrinò, Francesca Troilo, Daniela Bonetti, Angelo Toto, Stefano Gianni

Sci Rep. 2019; 9: 8279. Published online 2019 Jun 4. doi: 10.1038/s41598-019-44656-8

PMCID:: PMC6547694

Abstract Article PDF–1.3M

Select item 637271518.

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer

Xinran Li, Victor C. Y. Mak, Yuan Zhou, Chao Wang, Esther S. Y. Wong, Rakesh Sharma, Yiling Lu, Annie N. Y. Cheung, Gordon B. Mills, Lydia W. T. Cheung

Nat Commun. 2019; 10: 716. Published online 2019 Feb 12. doi: 10.1038/s41467-019-08574-7

PMCID:: PMC6372715

Abstract Article PDF–3.6M

Select item 602601519.

YAP/TAZ-mediated upregulation of GAB2 leads to increased sensitivity to growth factor-induced activation of the PI3K pathway

Chao Wang, Chao Gu, Kang Jin Jeong, Dong Zhang, Wei Guo, Yiling Lu, Zhenlin Ju, Nattapon Panupinthu, Ji Yeon Yang, Mihai (Mike) Gagea, Patrick Kwok Shing Ng, Fan Zhang, Gordon B. Mills

Cancer Res. Author manuscript; available in PMC 2018 Jun 29.

Published in final edited form as: Cancer Res. 2017 Apr 1; 77(7): 1637–1648. Published online 2017 Feb 15. doi: 10.1158/0008-5472.CAN-15-3084

PMCID:: PMC6026015

Abstract Article PDF–2.0M

Select item 582692620.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

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