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Items: 1 to 20 of 149

1.
ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression
Wenqian Xu, Feng Tian, Xiaolu Tai, Gaoxian Song, Yuanfang Liu, Liquan Fan, Xiangqin Weng, Eunjeong Yang, Meng Wang, Martin Bornhäuser, Chao Zhang, Richard B. Lock, Jason W.H. Wong, Jin Wang, Duohui Jing, Jian-Qing Mi
Haematologica. 2024 Aug 1; 109(8): 2445–2458. Published online 2024 Feb 15. doi: 10.3324/haematol.2023.284121
PMCID:
PMC11290521
AbstractArticlePDF–4.0M
2.
TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT‐7/GM
Wataru Takahashi, Ko Sasaki, Norio Komatsu, Kinuko Mitani
Cancer Sci. 2005 Jun; 96(6): 340–348. Published online 2005 Jun 15. doi: 10.1111/j.1349-7006.2005.00052.x
PMCID:
PMC11159770
AbstractArticlePDF–505K
3.
ETV6 fusions from insertions of exons 3-5 in pediatric hematologic malignancies
Sarah B. Mueller, Yana Pikman, Sarah K. Tasian, Lewis B. Silverman, Marian H. Harris, Harrison K. Tsai
Haematologica. 2023 Dec 1; 108(12): 3471–3476. Published online 2023 Jun 29. doi: 10.3324/haematol.2022.282498
PMCID:
PMC10690910
ArticlePDF–733K
4.
Hereditary platelet disorders associated with germ line variants in RUNX1, ETV6, and ANKRD26
Claire C. Homan, Hamish S. Scott, Anna L. Brown
Blood. 2023 Mar 30; 141(13): 1533–1543. Published online 2023 Jan 13. doi: 10.1182/blood.2022017735
PMCID:
PMC10651873
AbstractArticle
5.
Description of an Institutional Cohort of Myeloid Neoplasms Carrying ETV6-Locus Deletions or ETV6 Rearrangements
Vasiliki Papadopoulou, Jacqueline Schoumans, Ilaria Scarpelli, Sabine Blum
Acta Haematol. 2023 Feb 27; 146(5): 401–407. Published online 2023 Feb 27. doi: 10.1159/000529844
PMCID:
PMC10614221
AbstractArticle
6.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
7.
High-grade non-intestinal type sinonasal adenocarcinoma with ETV6::NTRK3 fusion, distinct from secretory carcinoma by immunoprofile and morphology
Natálie Klubíčková, Elaheh Mosaieby, Nikola Ptáková, Aude Trinquet, Marick Laé, Valérie Costes-Martineau, Alena Skálová
Virchows Arch. 2023; 483(2): 187–195. Published online 2023 Jul 6. doi: 10.1007/s00428-023-03587-6
PMCID:
PMC10412680
AbstractArticlePDF–2.4M
8.
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
Diana Y. Lu, Jana M. Ellegast, Kenneth N. Ross, Clare F. Malone, Shan Lin, Nathaniel W. Mabe, Neekesh V. Dharia, Ashleigh Meyer, Amy Conway, Angela H. Su, Julia Selich-Anderson, Cenny Taslim, Andrea K. Byrum, Bo Kyung A. Seong, Biniam Adane, Nathanael S. Gray, Miguel N. Rivera, Stephen L. Lessnick, Kimberly Stegmaier
Nat Cell Biol. 2023; 25(2): 285–297. Published online 2023 Jan 19. doi: 10.1038/s41556-022-01059-8
PMCID:
PMC9928584
AbstractArticlePDF–11M
9.
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells
Hila Fishman, Shreyas Madiwale, Ifat Geron, Vase Bari, Wouter Van Loocke, Yael Kirschenbaum, Itamar Ganmore, Eitan Kugler, Avigail Rein-Gil, Gilgi Friedlander, Ginette Schiby, Yehudit Birger, Sabine Strehl, Jean Soulier, Birgit Knoechel, Adolfo Ferrando, Sharon Noy-Lotan, Arnon Nagler, James C. Mulloy, Pieter Van Vlierberghe, Shai Izraeli
Blood. 2022 Jan 20; 139(3): 399–412. Published online 2021 Oct 12. doi: 10.1182/blood.2020010405
PMCID:
PMC9906988
AbstractArticle
10.
ETV3 and ETV6 enable monocyte differentiation into dendritic cells by repressing macrophage fate commitment
Javiera Villar, Adeline Cros, Alba De Juan, Lamine Alaoui, Pierre-Emmanuel Bonte, Colleen M. Lau, Ioanna Tiniakou, Boris Reizis, Elodie Segura
Nat Immunol. 2023; 24(1): 84–95. Published online 2022 Dec 21. doi: 10.1038/s41590-022-01374-0
PMCID:
PMC9810530
AbstractArticlePDF–18M
11.
Elevated ETV6 Expression in Glioma Promotes an Aggressive In Vitro Phenotype Associated with Shorter Patient Survival
Zhang Xiong, Shuai Wu, Feng-jiao Li, Chen Luo, Qiu-yan Jin, Ian David Connolly, Melanie Hayden Gephart, Linya You
Genes (Basel) 2022 Oct; 13(10): 1882. Published online 2022 Oct 17. doi: 10.3390/genes13101882
PMCID:
PMC9656946
AbstractArticlePDF–2.4M
12.
Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations
Michael W. Drazer, Claire C. Homan, Kai Yu, Marcela Cavalcante de Andrade Silva, Kelsey E. McNeely, Matthew J. Pozsgai, Maria G. Acevedo-Mendez, Jeremy P. Segal, Peng Wang, Jinghua Feng, Sarah L. King-Smith, Erika Kim, Sophia Korotev, David M. Lawrence, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Raman Sood, Elvira D.R.P. Velloso, Anna L. Brown, Paul P. Liu, Lucy A. Godley, NISC Comparative Sequencing Program
Blood Adv. 2022 Aug 9; 6(15): 4357–4359. Published online 2022 May 12. doi: 10.1182/bloodadvances.2022007211
PMCID:
PMC9636309
ArticlePDF–643K
13.
Platelet functional abnormalities and clinical presentation in pediatric patients with germline RUNX1, ANKRD26, and ETV6 mutations
Galina S. Ovsyannikova, Daria V. Fedorova, Ivan P. Tesakov, Alexey A. Martyanov, Anastasia A. Ignatova, Evgeniya A. Ponomarenko, Pavel A. Zharkov, Anna V. Pavlova, Elena V. Raykina, Michael A. Maschan, Mikhail A. Panteleev, Galina A. Novichkova, Anastasia N. Sveshnikova, Nataliya S. Smetanina
Haematologica. 2022 Oct 1; 107(10): 2511–2516. Published online 2022 Jul 7. doi: 10.3324/haematol.2022.281340
PMCID:
PMC9521247
ArticlePDF–5.7M
14.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
15.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
16.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
17.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
18.
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
Fabrizio Simeoni, Isabel Romero-Camarero, Francesco Camera, Fabio M.R. Amaral, Oliver J. Sinclair, Evangelia K. Papachristou, Gary J. Spencer, Michael Lie-A-Ling, Georges Lacaud, Daniel H. Wiseman, Jason S. Carroll, Tim C.P. Somervaille
Cell Rep. 2021 Sep 21; 36(12): 109725. Published online 2021 Sep 21. doi: 10.1016/j.celrep.2021.109725
PMCID:
PMC8480281
AbstractArticle
19.
N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas
Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.
Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017
PMCID:
PMC8282764
AbstractArticlePDF–3.4M
20.
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα
Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz
iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686
PMCID:
PMC8220391
AbstractArticlePDF–4.4M

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