PMC Links for GEO Profiles (Select 124250217) - PMC

Hongli Yin, Ozge Karayel, Ying-Yin Chao, Thomas Seeholzer, Isabel Hamp, Oliver Plettenburg, Torben Gehring, Christina Zielinski, Matthias Mann, Daniel Krappmann

Cell Mol Life Sci. 2022 Feb; 79(2): 112. Published online 2022 Jan 31. doi: 10.1007/s00018-022-04154-z

PMCID:: PMC8803816

Abstract Article PDF–9.2M

Select item 79209444.

Reconsidering Phosphorylation in the Control of Inducible CARD11 Scaffold Activity During Antigen Receptor Signaling

Joel L. Pomerantz

Adv Biol Regul. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Adv Biol Regul. 2021 Jan; 79: 100775. Published online 2020 Dec 18. doi: 10.1016/j.jbior.2020.100775

PMCID:: PMC7920944

Abstract Article PDF–297K

Select item 78206315.

Multiplexed Functional Assessment of Genetic Variants in CARD11

Iana Meitlis, Eric J. Allenspach, Bradly M. Bauman, Isabelle Q. Phan, Gina Dabbah, Erica G. Schmitt, Nathan D. Camp, Troy R. Torgerson, Deborah A. Nickerson, Michael J. Bamshad, David Hagin, Christopher R. Luthers, Jeffrey R. Stinson, Jessica Gray, Ingrid Lundgren, Joseph A. Church, Manish J. Butte, Mike B. Jordan, Seema S. Aceves, Daniella M. Schwartz, Joshua D. Milner, Susan Schuval, Suzanne Skoda-Smith, Megan A. Cooper, Lea M. Starita, David J. Rawlings, Andrew L. Snow, Richard G. James

Am J Hum Genet. 2020 Dec 3; 107(6): 1029–1043. Published online 2020 Nov 16. doi: 10.1016/j.ajhg.2020.10.015

PMCID:: PMC7820631

Abstract Article PDF–1.4M

Select item 77325086.

Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway

Daisuke Oikawa, Naoya Hatanaka, Takashi Suzuki, Fuminori Tokunaga

Front Immunol. 2020; 11: 601926. Published online 2020 Nov 23. doi: 10.3389/fimmu.2020.601926

PMCID:: PMC7732508

Abstract Article PDF–8.4M

Select item 76518627.

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway

Shiyu Chen, Zhiwei He, Changhao Zhu, Yanqing Liu, Lin Li, Lu Deng, Jun Wang, Chao Yu, Chengyi Sun

Front Oncol. 2020; 10: 554787. Published online 2020 Oct 16. doi: 10.3389/fonc.2020.554787

PMCID:: PMC7651862

Abstract Article PDF–5.4M

Select item 73580598.

Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly

Jeffrey R. Stinson, Batsukh Dorjbal, Dennis P. McDaniel, Liron David, Hao Wu, Andrew L. Snow

Cell Immunol. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Cell Immunol. 2020 Jul; 353: 104129. Published online 2020 May 14. doi: 10.1016/j.cellimm.2020.104129

PMCID:: PMC7358059

Abstract Article PDF–1.8M

Select item 69941199.

GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein

Jing Cheng, Linda R. Klei, Nathaniel E. Hubel, Ming Zhang, Rebekka Schairer, Lisa M. Maurer, Hanna B. Klei, Heejae Kang, Vincent J. Concel, Phillip C. Delekta, Eric V. Dang, Michelle A. Mintz, Mathijs Baens, Jason G. Cyster, Narayanan Parameswaran, Margot Thome, Peter C. Lucas, Linda M. McAllister-Lucas

J Clin Invest. 2020 Feb 3; 130(2): 1036–1051. Published online 2020 Jan 21. doi: 10.1172/JCI97040

PMCID:: PMC6994119

Abstract Article PDF–8.3M

Select item 688016010.

Host CARD11 Inhibits Newcastle Disease Virus Replication by Suppressing Viral Polymerase Activity in Neurons

Wenbin Wang, Xudong Chang, Wei Yao, Ning Wei, Na Huo, Yanhong Wang, Qiaolin Wei, Haijin Liu, Xinglong Wang, Shuxia Zhang, Zengqi Yang, Sa Xiao

J Virol. 2019 Dec 15; 93(24): e01499-19. Prepublished online 2019 Sep 25. Published online 2019 Nov 26. doi: 10.1128/JVI.01499-19

PMCID:: PMC6880160

Abstract Article PDF–13M

Select item 677943411.

Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling

Zhaoquan Wang, Shelby M. Hutcherson, Chao Yang, Rakhi P. Jattani, Julia M. Tritapoe, Yong-Kang Yang, Joel L. Pomerantz

J Biol Chem. 2019 Oct 4; 294(40): 14648–14660. Published online 2019 Aug 7. doi: 10.1074/jbc.RA119.009551

PMCID:: PMC6779434

Abstract Article PDF–3.3M

Select item 662426712.

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation

Michael J. Holliday, Axel Witt, Alejandro Rodríguez Gama, Benjamin T. Walters, Christopher P. Arthur, Randal Halfmann, Alexis Rohou, Erin C. Dueber, Wayne J. Fairbrother

Nat Commun. 2019; 10: 3070. Published online 2019 Jul 11. doi: 10.1038/s41467-019-10953-z

PMCID:: PMC6624267

Abstract Article PDF–5.4M

Select item 639554913.

Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease.

Batsukh Dorjbal, Jeffrey R. Stinson, Chi A. Ma, Michael A. Weinreich, Bahar Miraghazadeh, Julia M. Hartberger, Stefanie Frey-Jakobs, Stephan Weidinger, Lena Moebus, Andre Franke, Alejandro A. Schäffer, Alla Bulashevska, Sebastian Fuchs, Stephan Ehl, Sandhya Limaye, Peter D. Arkwright, Tracy A. Briggs, Claire Langley, Claire Bethune, Andrew F. Whyte, Hana Alachkar, Sergey Nejentsev, Thomas DiMaggio, Celeste G. Nelson, Kelly D. Stone, Martha Nason, Erica H. Brittain, Andrew J. Oler, Daniel P. Veltri, T. Ronan Leahy, Niall Conlon, Maria C. Poli, Arturo Borzutzky, Jeffrey I. Cohen, Joie Davis, Michele P. Lambert, Neil Romberg, Kathleen E. Sullivan, Kenneth Paris, Alexandra F. Freeman, Laura Lucas, Shanmuganathan Chandrakasan, Sinisa Savic, Sophie Hambleton, Smita Y Patel, Michael B. Jordan, Amy Theos, Jeffrey Lebensburger, T. Prescott Atkinson, Troy R. Torgerson, Ivan K. Chinn, Joshua D. Milner, Bodo Grimbacher, Matthew C. Cook, Andrew L. Snow

J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 Apr; 143(4): 1482–1495. Published online 2018 Aug 28. doi: 10.1016/j.jaci.2018.08.013

PMCID:: PMC6395549

Abstract Article PDF–1.0M

Select item 632887514.

Rare copy number variants in the genome of Chinese female children and adolescents with Turner syndrome

Li Li, Qingfeng Li, Qiong Wang, Li Liu, Ru Li, Huishu Liu, Yaojuan He, Gendie E. Lash

Biosci Rep. 2019 Jan 31; 39(1): BSR20181305. Prepublished online 2018 Dec 7. Published online 2019 Jan 11. doi: 10.1042/BSR20181305

PMCID:: PMC6328875

Abstract Article PDF–778K

Select item 616846115.

Molecular architecture and regulation of BCL10-MALT1 filaments

Florian Schlauderer, Thomas Seeholzer, Ambroise Desfosses, Torben Gehring, Mike Strauss, Karl-Peter Hopfner, Irina Gutsche, Daniel Krappmann, Katja Lammens

Nat Commun. 2018; 9: 4041. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06573-8

PMCID:: PMC6168461

Abstract Article PDF–3.7M

Select item 615646616.

The CBM-opathies—A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex

Henry Y. Lu, Bradly M. Bauman, Swadhinya Arjunaraja, Batsukh Dorjbal, Joshua D. Milner, Andrew L. Snow, Stuart E. Turvey

Front Immunol. 2018; 9: 2078. Published online 2018 Sep 19. doi: 10.3389/fimmu.2018.02078

PMCID:: PMC6156466

Abstract Article PDF–1.8M

Select item 615614317.

Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease

Jacquelyn R. Bedsaul, Nicole M. Carter, Katelynn E. Deibel, Shelby M. Hutcherson, Tyler A. Jones, Zhaoquan Wang, Chao Yang, Yong-Kang Yang, Joel L. Pomerantz

Front Immunol. 2018; 9: 2105. Published online 2018 Sep 19. doi: 10.3389/fimmu.2018.02105

PMCID:: PMC6156143

Abstract Article PDF–1.6M

Select item 581621518.

Assembly mechanism of the CARMA1–BCL10–MALT1–TRAF6 signalosome

Liron David, Yang Li, Jun Ma, Ethan Garner, Xinzheng Zhang, Hao Wu

Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7): 1499–1504. Published online 2018 Jan 30. doi: 10.1073/pnas.1721967115

PMCID:: PMC5816215

Abstract Article PDF–1.6M

Select item 581098419.

Genetic association study of NLRP1, CARD, and CASP1 inflammasome genes with chronic Chagas cardiomyopathy among Trypanosoma cruzi seropositive patients in Bolivia

Steven J. Clipman, Josephine Henderson-Frost, Katherine Y. Fu, Caryn Bern, Jorge Flores, Robert H. Gilman

PLoS One. 2018; 13(2): e0192378. Published online 2018 Feb 13. doi: 10.1371/journal.pone.0192378

PMCID:: PMC5810984

Abstract Article PDF–870K

Select item 566415220.

Germline hypomorphic CARD11 mutations in severe atopic disease

Chi A Ma, Jeffrey R Stinson, Yuan Zhang, Jordan K Abbott, Michael A Weinreich, Pia J Hauk, Paul R Reynolds, Jonathan J Lyons, Celeste G Nelson, Elisa Ruffo, Batsukh Dorjbal, Salomé Glauzy, Natsuko Yamakawa, Swadhinya Arjunaraja, Kelsey Voss, Jennifer Stoddard, Julie Niemela, Yu Zhang, Sergio D Rosenzweig, Joshua J McElwee, Thomas DiMaggio, Helen F Matthews, Nina Jones, Kelly D Stone, Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti, Brian Kim, Megan A Cooper, Neil D Romberg, Eric Meffre, Erwin W Gelfand, Andrew L Snow, Joshua D Milner

Nat Genet. Author manuscript; available in PMC 2017 Dec 19.

Published in final edited form as: Nat Genet. 2017 Aug; 49(8): 1192–1201. Published online 2017 Jun 19. doi: 10.1038/ng.3898

Correction in:: Nat Genet. 2017 Oct 27; 49(11): 1661.

PMCID:: PMC5664152

Abstract Article PDF–2.6M

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