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Select item 111627791.

Splicing analysis of STAT3 tandem donor suggests non-canonical binding registers for U1 and U6 snRNAs

Michal Kramárek, Přemysl Souček, Kamila Réblová, Lucie Kajan Grodecká, Tomáš Freiberger

Nucleic Acids Res. 2024 Jun 10; 52(10): 5959–5974. Published online 2024 Mar 1. doi: 10.1093/nar/gkae147

PMCID:: PMC11162779

Abstract Article PDF–2.8M

Select item 109902772.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 108703693.

Examining the capacity of human U1 snRNA variants to facilitate pre-mRNA splicing

Jason Wong, Ryan Yellamaty, Christina Gallante, Ethan Lawrence, William Martelly, Shalini Sharma

RNA. 2024 Mar; 30(3): 271–280. doi: 10.1261/rna.079892.123

PMCID:: PMC10870369

Abstract Article PDF–6.9M

Select item 75438864.

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Abhik K. Banerjee, Mario R. Blanco, Emily A. Bruce, Drew D. Honson, Linlin M. Chen, Amy Chow, Prashant Bhat, Noah Ollikainen, Sofia A. Quinodoz, Colin Loney, Jasmine Thai, Zachary D. Miller, Aaron E. Lin, Madaline M. Schmidt, Douglas G. Stewart, Daniel Goldfarb, Giuditta De Lorenzo, Suzannah J. Rihn, Rebecca M. Voorhees, Jason W. Botten, Devdoot Majumdar, Mitchell Guttman

Cell. 2020 Nov 25; 183(5): 1325–1339.e21. doi: 10.1016/j.cell.2020.10.004

PMCID:: PMC7543886

Abstract Article

Select item 59937975.

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed

Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3

PMCID:: PMC5993797

Abstract Article PDF–2.9M

Select item 56855496.

U1 snRNP telescripting regulates a size–function-stratified human genome

Jung-Min Oh, Chao Di, Christopher C Venters, Jiannan Guo, Chie Arai, Byung Ran So, Anna Maria Pinto, Zhenxi Zhang, Lili Wan, Ihab Younis, Gideon Dreyfuss

Nat Struct Mol Biol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Nat Struct Mol Biol. 2017 Nov; 24(11): 993–999. Published online 2017 Oct 2. doi: 10.1038/nsmb.3473

PMCID:: PMC5685549

Abstract Article PDF–732K

Select item 56785817.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 56487548.

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing

Xueni Li, Shiheng Liu, Jiansen Jiang, Lingdi Zhang, Sara Espinosa, Ryan C. Hill, Kirk C. Hansen, Z. Hong Zhou, Rui Zhao

Nat Commun. 2017; 8: 1035. Published online 2017 Oct 19. doi: 10.1038/s41467-017-01241-9

Correction in:: Nat Commun. 2018; 9: 1495.

PMCID:: PMC5648754

Abstract Article PDF–5.7M

Select item 51595309.

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease

Pilar Vazquez-Arango, Jane Vowles, Cathy Browne, Elizabeth Hartfield, Hugo J. R. Fernandes, Berhan Mandefro, Dhruv Sareen, William James, Richard Wade-Martins, Sally A. Cowley, Shona Murphy, Dawn O'Reilly

Nucleic Acids Res. 2016 Dec 15; 44(22): 10960–10973. Published online 2016 Aug 17. doi: 10.1093/nar/gkw711

PMCID:: PMC5159530

Abstract Article PDF–1.4M

Select item 399757210.

U1 small nuclear RNA variants differentially form ribonucleoprotein particles in vitro

Jason A. Somarelli, Annia Mesa, Carol E. Rodriguez, Shalini Sharma, Rene J. Herrera

Gene. Author manuscript; available in PMC 2015 Apr 25.

Published in final edited form as: Gene. 2014 Apr 25; 540(1): 11–15. Published online 2014 Feb 26. doi: 10.1016/j.gene.2014.02.054

PMCID:: PMC3997572

Abstract Article PDF–646K

Select item 393152811.

U1 snRNA Directly Interacts with Polypyrimidine Tract Binding Protein During Splicing Repression

Shalini Sharma, Christophe Maris, Frédéric H-T Allain, Douglas L. Black

Mol Cell. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Mol Cell. 2011 Mar 4; 41(5): 579–588. doi: 10.1016/j.molcel.2011.02.012

PMCID:: PMC3931528

Abstract Article PDF–2.9M

Select item 356186912.

Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

Dawn O'Reilly, Martin Dienstbier, Sally A. Cowley, Pilar Vazquez, Marek Drożdż, Stephen Taylor, William S. James, Shona Murphy

Genome Res. 2013 Feb; 23(2): 281–291. doi: 10.1101/gr.142968.112

PMCID:: PMC3561869

Abstract Article PDF–1.4M

Select item 355399513.

Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle

Nathalie Piazzon, Florence Schlotter, Suzie Lefebvre, Maxime Dodré, Agnès Méreau, Johann Soret, Aurore Besse, Martine Barkats, Rémy Bordonné, Christiane Branlant, Séverine Massenet

Nucleic Acids Res. 2013 Jan; 41(2): 1255–1272. Published online 2012 Dec 5. doi: 10.1093/nar/gks1224

PMCID:: PMC3553995

Abstract Article PDF–2.7M

Select item 341217414.

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

Michael G. Berg, Larry N. Singh, Ihab Younis, Qiang Liu, Anna Maria Pinto, Daisuke Kaida, Zhenxi Zhang, Sungchan Cho, Scott Sherrill-Mix, Lili Wan, Gideon Dreyfuss

Cell. Author manuscript; available in PMC 2013 Jan 6.

Published in final edited form as: Cell. 2012 Jul 6; 150(1): 53–64. doi: 10.1016/j.cell.2012.05.029

PMCID:: PMC3412174

Abstract Article PDF–3.9M

Select item 271948615.

Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA

Xavier Roca, Adrian R Krainer

Nat Struct Mol Biol. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Nat Struct Mol Biol. 2009 Feb; 16(2): 176–182. Published online 2009 Jan 25. doi: 10.1038/nsmb.1546

PMCID:: PMC2719486

Abstract Article PDF–1.5M

Select item 182938916.

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

Nastaran Behzadnia, Monika M Golas, Klaus Hartmuth, Bjoern Sander, Berthold Kastner, Jochen Deckert, Prakash Dube, Cindy L Will, Henning Urlaub, Holger Stark, Reinhard Lührmann

EMBO J. 2007 Mar 21; 26(6): 1737–1748. Published online 2007 Mar 1. doi: 10.1038/sj.emboj.7601631