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Select item 93434551.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 92885062.

Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance

Lidia Wrobel, Sandra M. Hill, Alvin Djajadikerta, Marian Fernandez-Estevez, Cansu Karabiyik, Avraham Ashkenazi, Victoria J. Barratt, Eleanna Stamatakou, Anders Gunnarsson, Timothy Rasmusson, Eric W. Miele, Nigel Beaton, Roland Bruderer, Yuehan Feng, Lukas Reiter, M. Paola Castaldi, Rebecca Jarvis, Keith Tan, Roland W. Bürli, David C. Rubinsztein

Nat Commun. 2022; 13: 4146. Published online 2022 Jul 16. doi: 10.1038/s41467-022-31905-0

PMCID:: PMC9288506

Abstract Article PDF–3.9M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 87266244.

CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression

Xuan Li, Kai-Bin Yang, Wei Chen, Jia Mai, Xiao-Qi Wu, Ting Sun, Rui-Yan Wu, Lin Jiao, Dan-Dan Li, Jiao Ji, Hai-Liang Zhang, Yan Yu, Yu-Hong Chen, Gong-Kan Feng, Rong Deng, Jun-Dong Li, Xiao-Feng Zhu

Autophagy. 2021; 17(12): 4323–4340. Published online 2021 May 12. doi: 10.1080/15548627.2021.1912270

PMCID:: PMC8726624

Abstract Article PDF–26M

Select item 86863925.

Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway

Lianguo Xue, Tao Jia, Yuanxin Zhu, Lidong Zhao, Jianping Mao

J Orthop Surg Res. 2021; 16: 723. Published online 2021 Dec 20. doi: 10.1186/s13018-021-02867-8

PMCID:: PMC8686392

Abstract Article PDF–6.8M

Select item 85464206.

The deubiquitinase USP11 is a versatile and conserved regulator of autophagy

Mila Basic, Alexandra Hertel, Justyna Bajdzienko, Florian Bonn, Mariana Tellechea, Alexandra Stolz, Andreas Kern, Christian Behl, Anja Bremm

J Biol Chem. 2021 Nov; 297(5): 101263. Published online 2021 Sep 30. doi: 10.1016/j.jbc.2021.101263

PMCID:: PMC8546420

Abstract Article PDF–2.4M

Select item 84965277.

ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis

Dongfang Li, Peter Vogel, Xiujie Li-Harms, Bo Wang, Mondira Kundu

Autophagy. 2021; 17(9): 2576–2585. Published online 2021 Apr 14. doi: 10.1080/15548627.2021.1911549

PMCID:: PMC8496527

Abstract Article PDF–3.0M

Select item 84306378.

ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells

JaeYung Lee, Jiyea Kim, Jeongeun Shin, YongHyun Kang, Jungwon Choi, Heesun Cheong

Int J Mol Sci. 2021 Sep; 22(17): 9182. Published online 2021 Aug 25. doi: 10.3390/ijms22179182

PMCID:: PMC8430637

Abstract Article PDF–4.8M

Select item 83948949.

SNAP47 Interacts with ATG14 to Promote VP1 Conjugation and CVB3 Propagation

Pinhao Xiang, Yasir Mohamud, Honglin Luo

Cells. 2021 Aug; 10(8): 2141. Published online 2021 Aug 20. doi: 10.3390/cells10082141

PMCID:: PMC8394894

Abstract Article PDF–2.4M

Select item 838674010.

Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy

Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda

Autophagy. 2021; 17(8): 2011–2036. Published online 2021 Jan 26. doi: 10.1080/15548627.2021.1874133

PMCID:: PMC8386740

Abstract Article PDF–13M

Select item 838661911.

STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I

Cefan Zhou, Xuehong Qian, Miao Hu, Rui Zhang, Nanxi Liu, Yuan Huang, Jing Yang, Juan Zhang, Hua Bai, Yuyan Yang, Yefu Wang, Declan Ali, Marek Michalak, Xing-Zhen Chen, Jingfeng Tang

Autophagy. 2020; 16(10): 1786–1806. Published online 2019 Nov 7. doi: 10.1080/15548627.2019.1687212

PMCID:: PMC8386619

Abstract Article PDF–10M

Select item 835328312.

ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication

Yafei Qu, Xin Wang, Yunkai Zhu, Weili Wang, Yuyan Wang, Gaowei Hu, Chengrong Liu, Jingjiao Li, Shanhui Ren, Maggie Z. X. Xiao, Zhenshan Liu, Chunxia Wang, Joyce Fu, Yucai Zhang, Ping Li, Rong Zhang, Qiming Liang

Front Cell Dev Biol. 2021; 9: 716208. Published online 2021 Jul 27. doi: 10.3389/fcell.2021.716208

PMCID:: PMC8353283

Abstract Article PDF–2.0M

Select item 832967213.

miR-424通过调控ATG14的表达抑制肝癌细胞的自噬和增殖

赵梓丹, 黄为, 和君建, 冯超

Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jul 20; 41(7): 1012–1021. Chinese. doi: 10.12122/j.issn.1673-4254.2021.07.07

PMCID:: PMC8329672

Abstract Article PDF–2.4M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 790011015.

HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation

Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang, Jing Xu, Hong Yang, Yuanchang Hu, Jiannan Qiu, Liyong Pu, Jinhai Tang, Xuehao Wang

Signal Transduct Target Ther. 2021; 6: 76. Published online 2021 Feb 23. doi: 10.1038/s41392-020-00453-8

PMCID:: PMC7900110

Abstract Article PDF–7.0M

Select item 783223516.

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Guangyan Miao, Hongyu Zhao, Yan Li, Mingming Ji, Yong Chen, Yi Shi, Yuhai Bi, Peihui Wang, Hong Zhang

Dev Cell. 2021 Feb 22; 56(4): 427–442.e5. Published online 2020 Dec 16. doi: 10.1016/j.devcel.2020.12.010

PMCID:: PMC7832235

Abstract Article PDF–5.9M

Select item 773761017.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 748081018.

Streptococcus pneumoniae promotes its own survival via choline-binding protein CbpC-mediated degradation of ATG14

Sayaka Shizukuishi, Michinaga Ogawa, Akihide Ryo, Makoto Ohnishi

Autophagy. 2020; 16(8): 1529–1531. Published online 2020 Jun 17. doi: 10.1080/15548627.2020.1776475

PMCID:: PMC7480810

Abstract Article PDF–1.0M

Select item 746944819.

A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3

Kejia Liu, Chu Guo, Yimin Lao, Jie Yang, Fei Chen, Yuzheng Zhao, Yi Yang, Jie Yang, Jing Yi

Autophagy. 2020; 16(6): 975–990. Published online 2019 Aug 2. doi: 10.1080/15548627.2019.1647944

PMCID:: PMC7469448

Abstract Article PDF–6.2M

Select item 738968420.

LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes

Cefan Zhou, Changhua Yi, Yongxiang Yi, Wenying Qin, Yanan Yan, Xueying Dong, Xuewen Zhang, Yuan Huang, Rui Zhang, Jie Wei, Declan William Ali, Marek Michalak, Xing-Zhen Chen, Jingfeng Tang

Mol Cancer. 2020; 19: 118. Published online 2020 Jul 29. doi: 10.1186/s12943-020-01237-y

PMCID:: PMC7389684

Abstract Article PDF–12M

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