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Select item 111483291.

The human alpha7 nicotinic acetylcholine receptor is a host target for the rabies virus glycoprotein

Brittany C. V. O’Brien, Shelly Thao, Lahra Weber, Helen L. Danielson, Agatha D. Boldt, Karsten Hueffer, Maegan M. Weltzin

Front Cell Infect Microbiol. 2024; 14: 1394713. Published online 2024 May 21. doi: 10.3389/fcimb.2024.1394713

PMCID:: PMC11148329

Abstract Article PDF–4.4M

Select item 108526612.

Effect of APOE and CHRNA7 Genotypes on the Cognitive Response to Cholinesterase Inhibitor Treatment at Different Stages of Alzheimer’s Disease

Ianna Lacerda Sampaio Braga, Patricia Natalia Silva, Tatiane Katsue Furuya, Leonardo Caires Santos, Belisa Caldana Pires, Diego Robles Mazzotti, Paulo Henrique Bertolucci, Maysa Seabra Cendoroglo, Marília Cardoso Smith

Am J Alzheimers Dis Other Demen. 2015 Mar; 30(2): 139–144. Published online 2014 Jun 20. doi: 10.1177/1533317514539540

PMCID:: PMC10852661

Abstract Article PDF–142K

Select item 100417673.

α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect

Huiyang Liu, Xiaomei Zhang, Peng Shi, Jiyuan Yuan, Qiang Jia, Chao Pi, Tao Chen, Linjin Xiong, Jinglin Chen, Jia Tang, Ruxu Yue, Zerong Liu, Hongping Shen, Ying Zuo, Yumeng Wei, Ling Zhao

J Neuroinflammation. 2023; 20: 84. Published online 2023 Mar 27. doi: 10.1186/s12974-023-02768-z

PMCID:: PMC10041767

Abstract Article PDF–2.2M

Select item 98501334.

The holistic approach to the CHRNA7 gene, hsa-miR-3158-5p, and 15q13.3 hotspot CNVs in migraineurs

Sedat Yasin, Şenay Görücü Yılmaz, Sırma Geyik, Sibel Oğuzkan Balcı

Mol Pain. 2023; 19: 17448069231152104. Published online 2023 Jan 17. doi: 10.1177/17448069231152104

PMCID:: PMC9850133

Abstract Article PDF–1.6M

Select item 92994155.

A Functional Interaction Between Y674-R685 Region of the SARS-CoV-2 Spike Protein and the Human α7 Nicotinic Receptor

Juan Facundo Chrestia, Ana Sofia Oliveira, Adrian J. Mulholland, Timothy Gallagher, Isabel Bermúdez, Cecilia Bouzat

Mol Neurobiol. 2022; 59(10): 6076–6090. Published online 2022 Jul 20. doi: 10.1007/s12035-022-02947-8

PMCID:: PMC9299415

Abstract Article PDF–30M

Select item 89291006.

Screening for Copy Number Variations of the 15q13.3 Hotspot in CHRNA7 Gene and Expression in Patients with Migraines

Mehmet Fatih Özaltun, Sırma Geyik, Şenay Görücü Yılmaz

Curr Issues Mol Biol. 2021 Sep; 43(2): 1090–1113. Published online 2021 Sep 7. doi: 10.3390/cimb43020078

PMCID:: PMC8929100

Abstract Article PDF–927K

Select item 88421657.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 88315968.

Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor

Vasyl Bondarenko, Marta M. Wells, Qiang Chen, Tommy S. Tillman, Kevin Singewald, Matthew J. Lawless, Joel Caporoso, Nicole Brandon, Jonathan A. Coleman, Sunil Saxena, Erik Lindahl, Yan Xu, Pei Tang

Nat Commun. 2022; 13: 793. Published online 2022 Feb 10. doi: 10.1038/s41467-022-28400-x

PMCID:: PMC8831596

Abstract Article PDF–1.7M

Select item 83173529.

Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7

Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner, John N. Constantino, Kristen L. Kroll

BMC Biol. 2021; 19: 147. Published online 2021 Jul 28. doi: 10.1186/s12915-021-01080-7

PMCID:: PMC8317352

Abstract Article PDF–14M

Select item 818339210.

Nicotinic α7 Acetylcholine Receptor (α7nAChR) in Human Airway Smooth Muscle

Niyati A. Borkar, Benjamin Roos, Y.S. Prakash, Venkatachalem Sathish, Christina M. Pabelick

Arch Biochem Biophys. Author manuscript; available in PMC 2022 Jul 30.

Published in final edited form as: Arch Biochem Biophys. 2021 Jul 30; 706: 108897. Published online 2021 May 15. doi: 10.1016/j.abb.2021.108897

PMCID:: PMC8183392

Abstract Article PDF–1.5M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 801192712.

Thermodynamics and Kinetics of Ion Permeation in Wild-Type and Mutated Open Active Conformation of the Human α7 Nicotinic Receptor

Grazia Cottone, Letizia Chiodo, Luca Maragliano

J Chem Inf Model. 2020 Oct 26; 60(10): 5045–5056. Published online 2020 Aug 17. doi: 10.1021/acs.jcim.0c00549

PMCID:: PMC8011927

Abstract Article PDF–4.7M

Select item 797953713.

Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling

Lu Wang, Liang Du, Xiao Xiong, Yusheng Lin, Jianlin Zhu, Zhimeng Yao, Shuhong Wang, Yi Guo, Yuping Chen, Kyla Geary, Yunlong Pan, Fuyou Zhou, Shegan Gao, Dianzheng Zhang, Sai-Ching Jim Yeung, Hao Zhang

Oncogene. 2021; 40(11): 1974–1987. Published online 2021 Feb 18. doi: 10.1038/s41388-021-01682-z

Correction in:: Oncogene. 2021; 40(34): 5356.

PMCID:: PMC7979537

Abstract Article PDF–5.3M

Select item 774671914.

The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper–zinc superoxide dismutase 1-mediated toxicity

Taisei Ito, Masatoshi Inden, Tomoyuki Ueda, Yuta Asaka, Hisaka Kurita, Isao Hozumi

Sci Rep. 2020; 10: 22157. Published online 2020 Dec 17. doi: 10.1038/s41598-020-79189-y

PMCID:: PMC7746719

Abstract Article PDF–6.0M

Select item 741140415.

Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells

Jia-Mou Ren, Shu-Li Zhang, Xiao-Ling Wang, Zhi-Zhong Guan, Xiao-Lan Qi

Mol Med Rep. 2020 Sep; 22(3): 2063–2075. Published online 2020 Jun 18. doi: 10.3892/mmr.2020.11253

PMCID:: PMC7411404

Abstract Article PDF–1.4M

Select item 739719616.

Profile of the Nicotinic Cholinergic Receptor Alpha 7 Subunit Gene Expression is Associated with Response to Varenicline Treatment

Juliana Rocha Santos, Paulo Roberto Xavier Tomaz, Jaqueline Ribeiro Scholz, Patrícia Viviane Gaya, Tânia Ogawa Abe, José Eduardo Krieger, Alexandre Costa Pereira, Paulo Caleb Júnior de Lima Santos

Genes (Basel) 2020 Jul; 11(7): 746. Published online 2020 Jul 6. doi: 10.3390/genes11070746

PMCID:: PMC7397196

Abstract Article PDF–437K

Select item 737170217.

Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

Yasuhiro Moriwaki, Natsuki Kubo, Mizuho Watanabe, Shinsuke Asano, Tomoki Shinoda, Taro Sugino, Daiju Ichikawa, Shoutaro Tsuji, Fusao Kato, Hidemi Misawa

Sci Rep. 2020; 10: 11996. Published online 2020 Jul 20. doi: 10.1038/s41598-020-68947-7