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Select item 112200181.

Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression

Hao Peng, Meng Yang, Kun Feng, Qingpeng Lv, Yewei Zhang

Signal Transduct Target Ther. 2024; 9: 169. Published online 2024 Jul 3. doi: 10.1038/s41392-024-01887-0

PMCID:: PMC11220018

Abstract Article PDF–9.2M

Select item 109637892.

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer

Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong

Sci Rep. 2024; 14: 7082. Published online 2024 Mar 25. doi: 10.1038/s41598-024-57854-w

PMCID:: PMC10963789

Abstract Article PDF–4.5M

Select item 106926503.

Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells

Parvin Yenki, Satyam Bhasin, Liang Liu, Noushin Nabavi, Chi Wing Cheng, Kevin J Tam, James W Peacock, Hans H Adomat, Tabitha Tombe, Ladan Fazli, Larissa Ivanova, Christopher Dusek, Shahram Khosravi, Emma S Tomlinson Guns, Yuzhuo Wang, Ralph Buttyan, Martin E Gleave, Christopher J Ong

Endocr Relat Cancer. 2023 Dec 1; 30(12): e230010. Prepublished online 2023 Oct 6. Published online 2023 Nov 6. doi: 10.1530/ERC-23-0010

PMCID:: PMC10692650

Abstract Article PDF–2.4M

Select item 101191664.

Sema3C signaling is an alternative activator of the canonical WNT pathway in glioblastoma

Jing Hao, Xiangzi Han, Haidong Huang, Xingjiang Yu, Jiankang Fang, Jianjun Zhao, Richard A. Prayson, Shideng Bao, Jennifer S. Yu

Nat Commun. 2023; 14: 2262. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37397-w

Correction in:: Nat Commun. 2023; 14: 6018.

PMCID:: PMC10119166

Abstract Article PDF–3.1M

Select item 99504475.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 95236456.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 94375637.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 92316238.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 90555719.

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)₂D₃ in osteoblasts

Jussi Ryynänen, Carsten Kriebitzsch, Mark B. Meyer, Iris Janssens, J. Wesley Pike, Lieve Verlinden, Annemieke Verstuyf

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Oct; 173: 185–193. Published online 2017 Feb 9. doi: 10.1016/j.jsbmb.2017.02.005

PMCID:: PMC9055571

Abstract Article PDF–1.9M

Select item 860437410.

MAOA Promotes Prostate Cancer Cell Perineural Invasion through SEMA3C/PlexinA2/NRP1-cMET Signaling

Lijuan Yin, Jingjing Li, Jing Wang, Tianjie Pu, Jing Wei, Qinlong Li, Boyang Jason Wu

Oncogene. Author manuscript; available in PMC 2021 Nov 19.

Published in final edited form as: Oncogene. 2021 Feb; 40(7): 1362–1374. Published online 2021 Jan 8. doi: 10.1038/s41388-020-01615-2

PMCID:: PMC8604374

Abstract Article PDF–1.9M

Select item 856647311.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 826354712.

Whole-genome sequencing identifies functional noncoding variation in SEMA3C that cosegregates with dyslexia in a multigenerational family

Amaia Carrion-Castillo, Sara B. Estruch, Ben Maassen, Barbara Franke, Clyde Francks, Simon E. Fisher

Hum Genet. 2021; 140(8): 1183–1200. Published online 2021 Jun 2. doi: 10.1007/s00439-021-02289-w

PMCID:: PMC8263547

Abstract Article PDF–1.2M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 799307614.

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor

Jin-Gu Lee, Weiliang Huang, Hangnoh Lee, Joyce van de Leemput, Maureen A. Kane, Zhe Han

Cell Biosci. 2021; 11: 58. Published online 2021 Mar 25. doi: 10.1186/s13578-021-00568-7

PMCID:: PMC7993076

Abstract Article PDF–2.0M

Select item 787676715.

Effect of semaphorin 3C gene variants in multifactorial Hirschsprung disease

Gunadi, Fiko Ryantono, Raman Sethi, Marcellus, Alvin Santoso Kalim, Priscillia Imelda, Devy Melati, Susan Simanjaya, William Widitjiarso, Ririd Tri Pitaka, Nur Arfian, Kristy Iskandar, Akhmad Makhmudi, Poh San Lai

J Int Med Res. 2021 Feb; 49(2): 0300060520987789. Published online 2021 Feb 8. doi: 10.1177/0300060520987789

PMCID:: PMC7876767

Abstract Article PDF–805K

Select item 787602016.

LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C

Luca Ducoli, Saumya Agrawal, Eliane Sibler, Tsukasa Kouno, Carlotta Tacconi, Chung-Chao Hon, Simone D. Berger, Daniela Müllhaupt, Yuliang He, Jihye Kim, Marco D’Addio, Lothar C. Dieterich, Piero Carninci, Michiel J. L. de Hoon, Jay W. Shin, Michael Detmar

Nat Commun. 2021; 12: 925. Published online 2021 Feb 10. doi: 10.1038/s41467-021-21217-0

PMCID:: PMC7876020

Abstract Article PDF–9.9M

Select item 782408617.

MiR-146a Regulates Migration and Invasion by Targeting NRP2 in Circulating-Tumor Cell Mimicking Suspension Cells

Yeojin Do, Jin Gu Cho, Ji Young Park, Sumin Oh, Doyeon Park, Kyung Hyun Yoo, Myeong-Sok Lee, Byung Su Kwon, Jongmin Kim, Young Yang

Genes (Basel) 2021 Jan; 12(1): 45. Published online 2020 Dec 30. doi: 10.3390/genes12010045

PMCID:: PMC7824086

Abstract Article PDF–2.7M

Select item 765928618.

Semaphorin 3C is involved in the progression of gastric cancer

Hideyo Miyato, Nelson Hirokazu Tsuno, Joji Kitayama

Cancer Sci. 2012 Nov; 103(11): 1961–1966. Published online 2012 Oct 15. doi: 10.1111/cas.12003

PMCID:: PMC7659286

Abstract Article PDF–1.7M

Select item 730510919.

Semaphorin 3 C is a Novel Adipokine Representing Exercise-Induced Improvements of Metabolism in Metabolically Healthy Obese Young Males

Ji Sun Nam, Chul Woo Ahn, Hye Jun Park, Yu Sik Kim

Sci Rep. 2020; 10: 10005. Published online 2020 Jun 19. doi: 10.1038/s41598-020-67004-7

PMCID:: PMC7305109

Abstract Article PDF–1.5M

Select item 728193520.

Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Sharadha Sakthikumar, Ananya Roy, Lulu Haseeb, Mats E. Pettersson, Elisabeth Sundström, Voichita D. Marinescu, Kerstin Lindblad-Toh, Karin Forsberg-Nilsson

Genome Biol. 2020; 21: 127. Published online 2020 Jun 9. doi: 10.1186/s13059-020-02035-x

PMCID:: PMC7281935

Abstract Article PDF–2.5M

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