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Select item 112099351.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 97404873.

RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer

Leslie Olmedo-Nieva, J. Omar Muñoz-Bello, Imelda Martínez-Ramírez, Antonio Daniel Martínez-Gutiérrez, Yunuen Ortiz-Pedraza, Claudia González-Espinosa, Vicente Madrid-Marina, Kirvis Torres-Poveda, Margarita Bahena-Roman, Marcela Lizano

Cells. 2022 Dec; 11(23): 3942. Published online 2022 Dec 6. doi: 10.3390/cells11233942

PMCID:: PMC9740487

Abstract Article PDF–4.7M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 70501035.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 62386396.

Ripor2 is involved in auditory hair cell stereociliary bundle structure and orientation

Oscar Diaz-Horta, Clemer Abad, Filiz Basak Cengiz, Guney Bademci, Pat Blackwelder, Katherina Walz, Mustafa Tekin

J Mol Med (Berl) Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: J Mol Med (Berl). 2018 Nov; 96(11): 1227–1238. Published online 2018 Oct 3. doi: 10.1007/s00109-018-1694-x

PMCID:: PMC6238639

Abstract Article PDF–1.4M

Select item 61417087.

Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration

Laura Megrelis, Elyas El Ghoul, Federica Moalli, Margaux Versapuech, Shamir Cassim, Nora Ruef, Jens V. Stein, Marianne Mangeney, Jérôme Delon

Front Immunol. 2018; 9: 2001. Published online 2018 Sep 11. doi: 10.3389/fimmu.2018.02001

PMCID:: PMC6141708

Abstract Article PDF–1.6M

Select item 53253588.

FAM65B controls the proliferation of transformed and primary T cells

Jeanne Froehlich, Margaux Versapuech, Laura Megrelis, Quitterie Largeteau, Sylvain Meunier, Corinne Tanchot, Georges Bismuth, Jérôme Delon, Marianne Mangeney

Oncotarget. 2016 Sep 27; 7(39): 63215–63225. Published online 2016 Aug 20. doi: 10.18632/oncotarget.11438

PMCID:: PMC5325358

Abstract Article PDF–2.5M

Select item 53096999.

Armc5 deletion causes developmental defects and compromises T-cell immune responses

Yan Hu, Linjiang Lao, Jianning Mao, Wei Jin, Hongyu Luo, Tania Charpentier, Shijie Qi, Junzheng Peng, Bing Hu, Mieczyslaw Martin Marcinkiewicz, Alain Lamarre, Jiangping Wu

Nat Commun. 2017; 8: 13834. Published online 2017 Feb 7. doi: 10.1038/ncomms13834

PMCID:: PMC5309699

Abstract Article PDF–2.2M

Select item 489893010.

Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function

Bo Zhao, Zizhen Wu, Ulrich Müller

eLife. 2016; 5: e14222. Published online 2016 Jun 8. doi: 10.7554/eLife.14222

PMCID:: PMC4898930

Abstract Article PDF–8.6M

Select item 463947211.

Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children

John D. Eicher, Angela M. Montgomery, Natacha Akshoomoff, David G. Amaral, Cinnamon S. Bloss, Ondrej Libiger, Nicholas J. Schork, Burcu F. Darst, B. J. Casey, Linda Chang, Thomas Ernst, Jean Frazier, Walter E. Kaufmann, Brian Keating, Tal Kenet, David Kennedy, Stewart Mostofsky, Sarah S. Murray, Elizabeth R. Sowell, Hauke Bartsch, Joshua M. Kuperman, Timothy T. Brown, Donald J. Hagler, Jr., Anders M. Dale, Terry L. Jernigan, Jeffrey R. Gruen, on behalf of the Pediatric Imaging Neurocognition Genetics study

Brain Imaging Behav. 2016; 10: 272–282. Published online 2015 May 9. doi: 10.1007/s11682-015-9392-6

PMCID:: PMC4639472

Abstract Article PDF–269K

Select item 434258112.

Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils

Kun Gao, Wenwen Tang, Yuan Li, Pingzhao Zhang, Dejie Wang, Long Yu, Chenji Wang, Dianqing Wu

J Cell Sci. 2015 Mar 1; 128(5): 992–1000. doi: 10.1242/jcs.161497

PMCID:: PMC4342581

Abstract Article

Select item 426658813.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 410332614.

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing

Oscar Diaz-Horta, Asli Subasioglu-Uzak, M’hamed Grati, Alexandra DeSmidt, Joseph Foster, II, Lei Cao, Guney Bademci, Suna Tokgoz-Yilmaz, Duygu Duman, F. Basak Cengiz, Clemer Abad, Rahul Mittal, Susan Blanton, Xue Z. Liu, Amjad Farooq, Katherina Walz, Zhongmin Lu, Mustafa Tekin

Proc Natl Acad Sci U S A. 2014 Jul 8; 111(27): 9864–9868. Published online 2014 Jun 23. doi: 10.1073/pnas.1401950111

PMCID:: PMC4103326

Abstract Article PDF–1.4M

Select item 406282215.

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation

Anuradha Balasubramanian, Genri Kawahara, Vandana A. Gupta, Anete Rozkalne, Ariane Beauvais, Louis M. Kunkel, Emanuela Gussoni

FASEB J. 2014 Jul; 28(7): 2955–2969. doi: 10.1096/fj.13-246470

PMCID:: PMC4062822

Abstract Article

Select item 366633816.

Family-based Genome-wide Association Study of Frontal Theta Oscillations Identifies Potassium Channel Gene KCNJ6

Sun J. Kang, Madhavi Rangaswamy, Niklas Manz, Jen-Chyong Wang, Leah Wetherill, Tony Hinrichs, Laura Almasy, Andy Brooks, David B. Chorlian, Danielle Dick, Victor Hesselbrock, John Kramer, Sam Kuperman, John Nurnberger, Jr, John Rice, Marc Schuckit, Jay Tischfield, Laura J. Bierut, Howard J. Edenberg, Alison Goate, Tatiana Foroud, Bernice Porjesz

Genes Brain Behav. Author manuscript; available in PMC 2013 May 29.

Published in final edited form as: Genes Brain Behav. 2012 Aug; 11(6): 712–719. Published online 2012 May 31. doi: 10.1111/j.1601-183X.2012.00803.x

PMCID:: PMC3666338

Abstract Article PDF–721K

Select item 326170817.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 318838818.

Leveraging the power of next-generation sequencing to generate interactome datasets

Haiyuan Yu, Leah Tardivo, Stanley Tam, Evan Weiner, Fana Gebreab, Changyu Fan, Nenad Svrzikapa, Tomoko Hirozane-Kishikawa, Edward Rietman, Xinping Yang, Julie Sahalie, Kourosh Salehi-Ashtiani, Tong Hao, Michael E. Cusick, David E. Hill, Frederick P. Roth, Pascal Braun, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Nat Methods. 2011 Jun; 8(6): 478–480. Published online 2011 Apr 24. doi: 10.1038/nmeth.1597

PMCID:: PMC3188388

Abstract Article PDF–932K

Select item 302425219.

PC3 prostate tumor-initiating cells with molecular profile FAM65B^high/MFI2^low/LEF1^lowincrease tumor angiogenesis

Kexiong Zhang, David J Waxman

Mol Cancer. 2010; 9: 319. Published online 2010 Dec 29. doi: 10.1186/1476-4598-9-319

PMCID:: PMC3024252

Abstract Article PDF–664K

Select item 296748920.

A Human MAP Kinase Interactome

Sourav Bandyopadhyay, Chih-yuan Chiang, Jyoti Srivastava, Merril Gersten, Suhaila White, Russell Bell, Cornelia Kurschner, Christopher H. Martin, Mike Smoot, Sudhir Sahasrabudhe, Diane L. Barber, Sumit K. Chanda, Trey Ideker

Nat Methods. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Nat Methods. 2010 Oct; 7(10): 801–805. doi: 10.1038/nmeth.1506

PMCID:: PMC2967489

Abstract Article PDF–1.2M

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