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Select item 106465511.

cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars M Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas, Domagoj Vucic, John Silke, Manolis Pasparakis, Hamid Kashkar

EMBO J. 2023 Nov; 42(22): e113614. Published online 2023 Oct 4. doi: 10.15252/embj.2023113614

PMCID:: PMC10646551

Abstract Article PDF–3.3M

Select item 99003332.

M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination

Yang Li, Yufan Wu, Ihsan Khan, Jianteng Zhou, Yue Lu, Jingwei Ye, Junyan Liu, Xuefeng Xie, Congyuan Hu, Hanwei Jiang, Suixing Fan, Huan Zhang, Yuanwei Zhang, Xiaohua Jiang, Bo Xu, Hui Ma, Qinghua Shi

EMBO Rep. 2023 Feb; 24(2): e55778. Published online 2022 Nov 28. doi: 10.15252/embr.202255778

PMCID:: PMC9900333

Abstract Article PDF–14M

Select item 92081013.

Cellular inhibitor of apoptosis 2 (cIAP2) restricts neuroinflammation during experimental autoimmune encephalomyelitis

Debolina D. Biswas, Rebecca K. Martin, LaShardai N. Brown, Karli Mockenhaupt, Angela S. Gupta, Michael J. Surace, Anuj Tharakan, Jessie W. Yester, Reetika Bhardwaj, Daniel H. Conrad, Tomasz Kordula

J Neuroinflammation. 2022; 19: 158. Published online 2022 Jun 19. doi: 10.1186/s12974-022-02527-6

PMCID:: PMC9208101

Abstract Article PDF–8.0M

Select item 87450524.

A Novel Role of BIRC3 in Stemness Reprogramming of Glioblastoma

Qiong Wu, Anders E. Berglund, Robert J. MacAulay, Arnold B. Etame

Int J Mol Sci. 2022 Jan; 23(1): 297. Published online 2021 Dec 28. doi: 10.3390/ijms23010297

PMCID:: PMC8745052

Abstract Article PDF–3.0M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78958326.

E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3

Peng Gao, Xianwei Ma, Ming Yuan, Yulan Yi, Guoke Liu, Mingyue Wen, Wei Jiang, Ruihua Ji, Lingxi Zhu, Zhen Tang, Qingzhuo Yu, Jing Xu, Rui Yang, Sheng Xia, Mingjin Yang, Jianping Pan, Hongbin Yuan, Huazhang An

Nat Commun. 2021; 12: 1194. Published online 2021 Feb 19. doi: 10.1038/s41467-021-21456-1

PMCID:: PMC7895832

Abstract Article PDF–2.4M

Select item 74159917.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 67978098.

Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development

Xueqing Liu, Veronica Castle, Teruko Taketo

Cell Death Dis. 2019 Nov; 10(11): 790. Published online 2019 Oct 17. doi: 10.1038/s41419-019-2019-x

PMCID:: PMC6797809

Abstract Article PDF–1.9M

Select item 65337269.

Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy

Neena Lala-Tabbert, Rim Lejmi-Mrad, Kristen Timusk, Marina Fukano, Janelle Holbrook, Martine St-Jean, Eric C. LaCasse, Robert G. Korneluk

Skelet Muscle. 2019; 9: 13. Published online 2019 May 24. doi: 10.1186/s13395-019-0201-6

PMCID:: PMC6533726

Abstract Article PDF–3.2M

Select item 594330010.

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes

Sylwia Gradzka, Oliver S. Thomas, Oliver Kretz, Aladin Haimovici, Lazaros. Vasilikos, Wendy Wei-Lynn Wong, Georg Häcker, Ian E. Gentle

Cell Death Dis. 2018 May; 9(5): 529. Published online 2018 May 9. doi: 10.1038/s41419-018-0508-y

PMCID:: PMC5943300

Abstract Article PDF–6.1M

Select item 582397511.

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Alessandro Annibaldi, Sidonie Wicky John, Tom Vanden Berghe, Kirby N. Swatek, Jianbin Ruan, Gianmaria Liccardi, Katiuscia Bianchi, Paul R. Elliott, Sze Men Choi, Samya Van Coillie, John Bertin, Hao Wu, David Komander, Peter Vandenabeele, John Silke, Pascal Meier

Mol Cell. 2018 Feb 15; 69(4): 566–580.e5. doi: 10.1016/j.molcel.2018.01.027

PMCID:: PMC5823975

Abstract Article

Select item 575721912.

Shigella hijacks the glomulin–cIAPs–inflammasome axis to promote inflammation

Shiho Suzuki, Toshihiko Suzuki, Hitomi Mimuro, Tsunehiro Mizushima, Chihiro Sasakawa

EMBO Rep. 2018 Jan; 19(1): 89–101. Published online 2017 Nov 30. doi: 10.15252/embr.201643841

PMCID:: PMC5757219

Abstract Article PDF–2.9M

Select item 552073613.

DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues

Valérie Glorian, Jennifer Allègre, Jean Berthelet, Baptiste Dumetier, Pierre-Marie Boutanquoi, Nathalie Droin, Cémile Kayaci, Jessy Cartier, Simon Gemble, Guillaume Marcion, Daniel Gonzalez, Romain Boidot, Carmen Garrido, Olivier Michaud, Eric Solary, Laurence Dubrez

Cell Death Dis. 2017 May; 8(5): e2816. Published online 2017 May 25. doi: 10.1038/cddis.2017.222

Correction in:: Cell Death Dis. 2018 Aug; 9(8): 785.

PMCID:: PMC5520736

Abstract Article PDF–2.0M

Select item 538636914.

Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice

Maria Eugenia Guicciardi, Anuradha Krishnan, Steven F Bronk, Petra Hirsova, Thomas S Griffith, Gregory J Gores

Cell Death Dis. 2017 Jan; 8(1): e2535. Published online 2017 Jan 5. doi: 10.1038/cddis.2016.459

PMCID:: PMC5386369

Abstract Article PDF–7.8M

Select item 535504615.

Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma

Loyola V. Gressot, Tiffany Doucette, Yuhui Yang, Gregory N. Fuller, Ganiraju Manyam, Arvind Rao, Khatri Latha, Ganesh Rao

Oncotarget. 2017 Feb 21; 8(8): 12695–12704. Published online 2016 Apr 8. doi: 10.18632/oncotarget.8657

PMCID:: PMC5355046

Abstract Article PDF–3.3M

Select item 508512516.

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα

Tanmay M. Shekhar, Mark A. Miles, Ankita Gupte, Scott Taylor, Brianna Tascone, Carl R. Walkley, Christine J. Hawkins

Oncotarget. 2016 Jun 7; 7(23): 33866–33886. Published online 2016 Apr 25. doi: 10.18632/oncotarget.8980

PMCID:: PMC5085125

Abstract Article PDF–8.3M

Select item 456286617.

c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8⁺ memory T-cell survival

Maria Letizia Giardino Torchia, Ivana Munitic, Ehydel Castro, Jasmin Herz, Dorian B. McGavern, Jonathan D. Ashwell

Eur J Immunol. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Eur J Immunol. 2015 Sep; 45(9): 2672–2682. Published online 2015 Jul 7. doi: 10.1002/eji.201445342

PMCID:: PMC4562866

Abstract Article PDF–701K

Select item 445416018.

Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

E Kavanagh, J Rodhe, M A Burguillos, J L Venero, B Joseph

Cell Death Dis. 2014 Dec; 5(12): e1565. Published online 2014 Dec 11. doi: 10.1038/cddis.2014.514

PMCID:: PMC4454160

Abstract Article PDF–934K

Select item 442646119.

Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus

Gregor Ebert, Simon Preston, Cody Allison, James Cooney, Jesse G. Toe, Michael D. Stutz, Samar Ojaimi, Hamish W. Scott, Nikola Baschuk, Ueli Nachbur, Joseph Torresi, Ruth Chin, Danielle Colledge, Xin Li, Nadia Warner, Peter Revill, Scott Bowden, John Silke, C. Glenn Begley, Marc Pellegrini

Proc Natl Acad Sci U S A. 2015 May 5; 112(18): 5797–5802. Published online 2015 Apr 20. doi: 10.1073/pnas.1502390112

PMCID:: PMC4426461

Abstract Article PDF–1.1M

Select item 434663020.

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E. Lawlor, Nufail Khan, Alison Mildenhall, Motti Gerlic, Ben A. Croker, Akshay A. D’Cruz, Cathrine Hall, Sukhdeep Kaur Spall, Holly Anderton, Seth L. Masters, Maryam Rashidi, Ian P. Wicks, Warren S. Alexander, Yasuhiro Mitsuuchi, Christopher A. Benetatos, Stephen M. Condon, W. Wei-Lynn Wong, John Silke, David L. Vaux, James E. Vince

Nat Commun. 2015 Feb 18; 6: 6282. Published online 2015 Feb 18. doi: 10.1038/ncomms7282

PMCID:: PMC4346630

Abstract Article PDF–12M

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