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Select item 107258901.

Overexpression of microRNA-205-5p promotes cholangiocarcinoma growth by reducing expression of homeodomain-interacting protein kinase 3

Aye Myat Mon, Kitti Intuyod, Sirinapha Klungsaeng, Apinya Jusakul, Thatsanapong Pongking, Worachart Lert-itthiporn, Vor Luvira, Chawalit Pairojkul, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang, Somchai Pinlaor, Porntip Pinlaor

Sci Rep. 2023; 13: 22444. Published online 2023 Dec 17. doi: 10.1038/s41598-023-49694-x

PMCID:: PMC10725890

Abstract Article PDF–2.7M

Select item 106833552.

CircHIPK3 relieves vascular calcification via mediating SIRT1/PGC-1α/MFN2 pathway by interacting with FUS

Siyi Feng, Youfei Qi, Zhanxiang Xiao, Hao Chen, Sahua Liu, Haimei Luo, Hongfei Wu, Wenbo Zhang

BMC Cardiovasc Disord. 2023; 23: 583. Published online 2023 Nov 27. doi: 10.1186/s12872-023-03602-3

PMCID:: PMC10683355

Abstract Article PDF–7.4M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98727874.

DNA methylation change of HIPK3 in Chinese rheumatoid arthritis and its effect on inflammation

Ping Jiang, Kai Wei, Lingxia Xu, Cen Chang, Runrun Zhang, Jianan Zhao, Yehua Jin, Linshuai Xu, Yiming Shi, Yi Qian, Songtao Sun, Shicheng Guo, Rongsheng Wang, Yingying Qin, Dongyi He

Front Immunol. 2022; 13: 1087279. Published online 2023 Jan 10. doi: 10.3389/fimmu.2022.1087279

PMCID:: PMC9872787

Abstract Article PDF–1.8M

Select item 96913695.

circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR

Fengzhi Ding, Lin Lu, Chengjie Wu, Xiangbin Pan, Bin Liu, Yu Zhang, Yanli Wang, Weiliang Wu, Bing Yan, Yuqing Zhang, Xi-Yong Yu, Yangxin Li

Theranostics. 2022; 12(17): 7550–7566. Published online 2022 Oct 31. doi: 10.7150/thno.77630

PMCID:: PMC9691369

Abstract Article PDF–2.7M

Select item 94368996.

CircHIPK3 prevents chondrocyte apoptosis and cartilage degradation by sponging miR‐30a‐3p and promoting PON2

Jie Shang, Huizi Li, Biao Wu, Ning Jiang, Bin Wang, Dawei Wang, Junlong Zhong, Yufeng Chen, Xianghe Xu, Huading Lu

Cell Prolif. 2022 Sep; 55(9): e13285. Published online 2022 Jun 18. doi: 10.1111/cpr.13285

PMCID:: PMC9436899

Abstract Article PDF–4.5M

Select item 87829617.

Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy

Xiaodan Zhang, Xue Wen, Ismael Al-Ramahi, Juan Botas, Boxun Lu, Yuhua Fu

Neurosci Bull. 2022 Jan; 38(1): 99–103. Published online 2021 Nov 5. doi: 10.1007/s12264-021-00783-9

Correction in:: Neurosci Bull. 2022 Sep; 38(9): 1123.

PMCID:: PMC8782961

Article PDF–1.2M

Select item 87141338.

Endothelial cell–derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway

Shaohua Wang, Min Shi, Jiao Li, Yuanyuan Zhang, Wenjing Wang, Peixin Xu, Yongjun Li

Aging (Albany NY) 2021 Dec 15; 13(23): 25241–25255. Published online 2021 Dec 10. doi: 10.18632/aging.203742

PMCID:: PMC8714133

Abstract Article PDF–1.3M

Select item 85953729.

Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation

Ines H. Kaltheuner, Kanchan Anand, Jonas Moecking, Robert Düster, Jinhua Wang, Nathanael S. Gray, Matthias Geyer

Nat Commun. 2021; 12: 6607. Published online 2021 Nov 16. doi: 10.1038/s41467-021-26935-z

PMCID:: PMC8595372

Abstract Article PDF–3.6M

Select item 790616310.

Identification of HIPK3 as a potential biomarker and an inhibitor of clear cell renal cell carcinoma

Wen Xiao, Tao Wang, Yuzhong Ye, Xuegang Wang, Bin Chen, Jinchun Xing, Hongmei Yang, Xiaoping Zhang

Aging (Albany NY) 2021 Feb 15; 13(3): 3536–3553. Published online 2021 Jan 20. doi: 10.18632/aging.202294

PMCID:: PMC7906163

Abstract Article PDF–2.4M

Select item 701836411.

Down-regulation of circular RNA ITCH and circHIPK3 in gastric cancer tissues

Sara GHASEMI, Modjtaba EMADI-BAYGI, Parvaneh NIKPOUR

Turk J Med Sci. 2019; 49(2): 687–695. Published online 2018 Apr 18. doi: 10.3906/sag-1806-50

PMCID:: PMC7018364

Abstract Article PDF–541K

Select item 683843612.

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637

Yanli Zhang, Chen Li, Xinfeng Liu, Yanlei Wang, Rui Zhao, Yongmei Yang, Xin Zheng, Yi Zhang, Xin Zhang

EBioMedicine. 2019 Oct; 48: 277–288. Published online 2019 Oct 17. doi: 10.1016/j.ebiom.2019.09.051

PMCID:: PMC6838436

Abstract Article PDF–4.0M

Select item 597294313.

环状RNA CircHIPK3通过miR-379调控IGF1表达促进非小细胞肺癌细胞系NCI-H1299与NCI-H2170的细胞增殖

田芳, 王云, 肖哲, 朱学军

Zhongguo Fei Ai Za Zhi. 2017 Jul 20; 20(7): 459–467. Chinese. doi: 10.3779/j.issn.1009-3419.2017.07.04

PMCID:: PMC5972943

Abstract Article PDF–1.3M

Select item 584654814.

HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease

Yuhua Fu, Xiaoli Sun, Boxun Lu

Autophagy. 2018; 14(1): 169–170. Published online 2018 Jan 29. doi: 10.1080/15548627.2017.1393130

PMCID:: PMC5846548

Abstract Article PDF–393K

Select item 582692615.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 571740016.

Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models

Meng Yu, Yuhua Fu, Yijiang Liang, Haikun Song, Yao Yao, Peng Wu, Yuwei Yao, Yuyin Pan, Xue Wen, Lixiang Ma, Saiyin Hexige, Yu Ding, Shouqing Luo, Boxun Lu

Cell Res. 2017 Dec; 27(12): 1441–1465. Published online 2017 Oct 13. doi: 10.1038/cr.2017.113

PMCID:: PMC5717400

Abstract Article PDF–17M

Select item 567858117.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 557947018.

CircHIPK3 sponges miR‐558 to suppress heparanase expression in bladder cancer cells

Yawei Li, Fuxin Zheng, Xingyuan Xiao, Fei Xie, Dan Tao, Chao Huang, Dong Liu, Miao Wang, Liang Wang, Fuqing Zeng, Guosong Jiang

EMBO Rep. 2017 Sep; 18(9): 1646–1659. Published online 2017 Aug 9. doi: 10.15252/embr.201643581

Correction in:: EMBO Rep. 2022 Nov; 23(11): e56102.

PMCID:: PMC5579470

Abstract Article PDF–2.8M

Select item 549871719.

Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP

Sara Contreras-Martos, Alessandro Piai, Simone Kosol, Mihaly Varadi, Angela Bekesi, Pierre Lebrun, Alexander N. Volkov, Kris Gevaert, Roberta Pierattelli, Isabella C. Felli, Peter Tompa

Sci Rep. 2017; 7: 4676. Published online 2017 Jul 5. doi: 10.1038/s41598-017-04611-x

PMCID:: PMC5498717

Abstract Article PDF–3.7M

Select item 549522520.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114