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Items: 1 to 20 of 33

1.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
2.
G Protein-Coupled Receptor 75 (GPR75) As a Novel Molecule for Targeted Therapy of Cancer and Metabolic Syndrome
Mohammad-Reza Dashti, Fatemeh Ghorbanzadeh, Davoud Jafari-Gharabaghlou, Mahdi Farhoudi-Sefidan-Jadid, Nosratollah Zarghami
Asian Pac J Cancer Prev. 2023; 24(5): 1817–1825. doi: 10.31557/APJCP.2023.24.5.1817
PMCID:
PMC10495892
AbstractArticlePDF–579K
3.
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
Parsa Akbari, Ankit Gilani, Olukayode Sosina, Jack A. Kosmicki, Lori Khrimian, Yi-Ya Fang, Trikaldarshi Persaud, Victor Garcia, Dylan Sun, Alexander Li, Joelle Mbatchou, Adam E. Locke, Christian Benner, Niek Verweij, Nan Lin, Sakib Hossain, Kevin Agostinucci, Jonathan V. Pascale, Ercument Dirice, Michael Dunn, Regeneron Genetics Center, DiscovEHR Collaboration, William E. Kraus, Svati H. Shah, Yii-Der I. Chen, Jerome I. Rotter, Daniel J. Rader, Olle Melander, Christopher D. Still, Tooraj Mirshahi, David J. Carey, Jaime Berumen-Campos, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Suganthi Balasubramanian, Alicia Hawes, Marcus Jones, Brian Zambrowicz, Andrew J. Murphy, Charles Paulding, Giovanni Coppola, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Michael Cantor, Hyun M. Kang, Goncalo R. Abecasis, Katia Karalis, Aris N. Economides, Jonathan Marchini, George D. Yancopoulos, Mark W. Sleeman, Judith Altarejos, Giusy Della Gatta, Roberto Tapia-Conyer, Michal L. Schwartzman, Aris Baras, Manuel A. R. Ferreira, Luca A. Lotta
Science. Author manuscript; available in PMC 2023 Jun 16.
Published in final edited form as: Science. 2021 Jul 2; 373(6550): eabf8683. doi: 10.1126/science.abf8683
PMCID:
PMC10275396
AbstractArticlePDF–2.1M
4.
Uncovering the signalling, structure and function of the 20-HETE-GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75
Jonathan V. Pascale, Eon Joo Park, Adeniyi Michael Adebesin, John R. Falck, Michal Laniado Schwartzman, Victor Garcia
Br J Pharmacol. Author manuscript; available in PMC 2023 Apr 21.
Published in final edited form as: Br J Pharmacol. 2021 Sep; 178(18): 3813–3828. Published online 2021 Jun 15. doi: 10.1111/bph.15525
PMCID:
PMC10119890
AbstractArticlePDF–2.1M
5.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Ruth Hüttenhain, Jiewei Xu, Lily A. Burton, David E. Gordon, Judd F. Hultquist, Jeffrey R. Johnson, Laura Satkamp, Joseph Hiatt, David Y. Rhee, Kheewoong Baek, David C. Crosby, Alan D. Frankel, Alexander Marson, J. Wade Harper, Arno F. Alpi, Brenda A. Schulman, John D. Gross, Nevan J. Krogan
Cell Host Microbe. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Cell Host Microbe. 2019 Jul 10; 26(1): 86–99.e7. Published online 2019 Jun 25. doi: 10.1016/j.chom.2019.05.008
PMCID:
PMC7153695
AbstractArticlePDF–2.6M
10.
GPR75 RECEPTOR MEDIATES 20-HETE-SIGNALING AND METASTATIC FEATURES OF ANDROGEN-INSENSITIVE PROSTATE CANCER CELLS
Sofia Cárdenas, Cecilia Colombero, Laura Panelo, Rambabu Dakarapu, Falck John R., Costas Monica A., Susana Nowicki
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb; 1865(2): 158573. Published online 2019 Nov 21. doi: 10.1016/j.bbalip.2019.158573
PMCID:
PMC6957769
AbstractArticlePDF–1.4M
11.
The Orphan G Protein-coupled Receptor 75 Signaling is Activated by the Chemokine CCL5
Dr. Simona Dedoni, Dr. Lee A. Campbell, Dr. Brandon K. Harvey, Dr. Valeria Avdoshina, Dr. Italo Mocchetti
J Neurochem. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: J Neurochem. 2018 Sep; 146(5): 526–539. Published online 2018 Aug 2. doi: 10.1111/jnc.14463
PMCID:
PMC6198807
AbstractArticlePDF–1.9M
12.
The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin
Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342
PMCID:
PMC6076439
AbstractArticlePDF–2.5M
13.
CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia
Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu
Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6
PMCID:
PMC6039501
AbstractArticlePDF–2.7M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
20- HETE Signals Through G Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension
Victor Garcia, Ankit Gilani, Brian Shkolnik, Varunkumar Pandey, Frank Fan Zhang, Rambabu Dakarapu, Shyam K. Gandham, N. Rami Reddy, Joan P. Graves, Artiom Gruzdev, Darryl C. Zeldin, Jorge H. Capdevila, John R. Falck, Michal Laniado Schwartzman
Circ Res. Author manuscript; available in PMC 2018 May 26.
Published in final edited form as: Circ Res. 2017 May 26; 120(11): 1776–1788. Published online 2017 Mar 21. doi: 10.1161/CIRCRESAHA.116.310525
PMCID:
PMC5446268
AbstractArticlePDF–1.2M
16.
The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells
Wu-Ying Du, Zhen-Hai Lu, Wen Ye, Xiang Fu, Yi Zhou, Chun-Mei Kuang, Jiang-Xue Wu, Zhi-Zhong Pan, Shuai Chen, Ran-Yi Liu, Wen-Lin Huang
Chin J Cancer. 2017; 36: 11. Published online 2017 Jan 14. doi: 10.1186/s40880-017-0180-0
PMCID:
PMC5237493
AbstractArticlePDF–6.7M
17.
Genome-Wide Association Study of Short-Acting β2-Agonists. A Novel Genome-Wide Significant Locus on Chromosome 2 near ASB3
Elliot Israel, Jessica Lasky-Su, Amy Markezich, Amy Damask, Stanley J. Szefler, Brooke Schuemann, Barbara Klanderman, Jody Sylvia, Shamsah Kazani, Rongling Wu, Fernando Martinez, Homer A. Boushey, Vernon M. Chinchilli, Dave Mauger, Scott T. Weiss, Kelan G. Tantisira
Am J Respir Crit Care Med. 2015 Mar 1; 191(5): 530–537. Published online 2015 Mar 1. doi: 10.1164/rccm.201408-1426OC
PMCID:
PMC4384768
AbstractArticlePDF–1.0M
18.
Phospho-tyrosine dependent protein–protein interaction network
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl
Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968
PMCID:
PMC4380928
AbstractArticlePDF–1.9M
19.
Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase
Christina Aaen Andresen, Stine Smedegaard, Kathrine Beck Sylvestersen, Charlotte Svensson, Diego Iglesias-Gato, Giuseppe Cazzamali, Tine Kragh Nielsen, Michael Lund Nielsen, Amilcar Flores-Morales
J Biol Chem. 2014 Jan 24; 289(4): 2043–2054. Published online 2013 Dec 11. doi: 10.1074/jbc.M113.534602
PMCID:
PMC3900953
AbstractArticlePDF–1.7M
20.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M

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