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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
3.
Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation
Ana del Puerto, Julia Pose-Utrilla, Ana Simón-García, Celia López-Menéndez, Antonio J. Jiménez, Eva Porlan, Luis S. M. Pajuelo, Guillermo Cano-García, Beatriz Martí-Prado, Álvaro Sebastián-Serrano, Marina P. Sánchez-Carralero, Fabrizia Cesca, Giampietro Schiavo, Isidro Ferrer, Isabel Fariñas, Miguel R. Campanero, Teresa Iglesias
Mol Psychiatry. 2021; 26(11): 6411–6426. Published online 2021 May 17. doi: 10.1038/s41380-021-01127-9
PMCID:
PMC8760065
AbstractArticlePDF–5.5M
4.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang
Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5
PMCID:
PMC8314547
AbstractArticlePDF–3.7M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Characterization of the interaction between β-catenin and sorting nexin 27: contribution of the type I PDZ-binding motif to Wnt signaling
Brian J. DuChez, Christina L. Hueschen, Seth P. Zimmerman, Yvonne Baumer, Stephen Wincovitch, Martin P. Playford
Biosci Rep. 2019 Nov 29; 39(11): BSR20191692. Published online 2019 Nov 13. doi: 10.1042/BSR20191692
PMCID:
PMC6851508
AbstractArticlePDF–2.1M
7.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
8.
Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation
Yuzhe Zeng, Nawen Wang, Tiantian Guo, Qiuyang Zheng, Shuang Wang, Songsong Wu, Xi Li, Jin Wu, Zhida Chen, Huaxi Xu, Xin Wang, Bin Lin
Front Neurol. 2018; 9: 1059. Published online 2018 Dec 13. doi: 10.3389/fneur.2018.01059
PMCID:
PMC6300502
AbstractArticlePDF–5.4M
9.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
10.
GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization
Robert A. Rifkin, Deborah Huyghe, Xiaofan Li, Manasa Parakala, Erin Aisenberg, Stephen J. Moss, Paul A. Slesinger
Proc Natl Acad Sci U S A. 2018 Oct 2; 115(40): E9479–E9488. Published online 2018 Sep 18. doi: 10.1073/pnas.1807788115
PMCID:
PMC6176583
AbstractArticlePDF–1.3M
11.
SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes
M. Tello-Lafoz, C. Rodríguez-Rodríguez, G. Kinna, L. S. Loo, W. Hong, B. M. Collins, R. D. Teasdale, I. Mérida
Sci Rep. 2017; 7: 16361. Published online 2017 Nov 27. doi: 10.1038/s41598-017-16370-w
PMCID:
PMC5703713
AbstractArticlePDF–3.4M
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis
Xin Wang, Ying Zhou, Jian Wang, I-Chu Tseng, Timothy Huang, Yingjun Zhao, Qiuyang Zheng, Yue Gao, Hong Luo, Xian Zhang, Guojun Bu, Wanjin Hong, Huaxi Xu
J Neurosci. 2016 Dec 14; 36(50): 12586–12597. doi: 10.1523/JNEUROSCI.1620-16.2016
PMCID:
PMC5157104
AbstractArticlePDF–4.5M
14.
SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein
Timothy Y. Huang, Yingjun Zhao, Xiaoguang Li, Xin Wang, I-Chu Tseng, Robert Thompson, Shichun Tu, Thomas E. Willnow, Yun-wu Zhang, Huaxi Xu
J Neurosci. 2016 Jul 27; 36(30): 7996–8011. doi: 10.1523/JNEUROSCI.0206-16.2016
PMCID:
PMC4961782
AbstractArticlePDF–5.4M
15.
Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth
Audrey S. M. Chan, Thomas Clairfeuille, Euphemie Landao-Bassonga, Genevieve Kinna, Pei Ying Ng, Li Shen Loo, Tak Sum Cheng, Minghao Zheng, Wanjin Hong, Rohan D. Teasdale, Brett M. Collins, Nathan J. Pavlos
Mol Biol Cell. 2016 Apr 15; 27(8): 1367–1382. doi: 10.1091/mbc.E15-12-0851
PMCID:
PMC4831889
AbstractArticlePDF–2.9M
16.
Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation
Maria Merkulova, Teodor G. Păunescu, Anie Azroyan, Vladimir Marshansky, Sylvie Breton, Dennis Brown
Sci Rep. 2015; 5: 14827. Published online 2015 Oct 7. doi: 10.1038/srep14827
PMCID:
PMC4595830
AbstractArticlePDF–1.5M
17.
Sorting Nexin 27 Regulates Aβ Production through Modulating γ-secretase Activity
Xin Wang, Timothy Huang, Yingjun Zhao, Qiuyang Zheng, Robert C. Thompson, Guojun Bu, Yun-wu Zhang, Wanjin Hong, Huaxi Xu
Cell Rep. Author manuscript; available in PMC 2015 Feb 14.
Published in final edited form as: Cell Rep. 2014 Nov 6; 9(3): 1023–1033. Published online 2014 Oct 23. doi: 10.1016/j.celrep.2014.09.037
PMCID:
PMC4328673
AbstractArticlePDF–2.2M
18.
Sorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junction
Seth P. Zimmerman, Christina L. Hueschen, Daniela Malide, Sharon L. Milgram, Martin P. Playford
Biochem J. Author manuscript; available in PMC 2015 Jan 7.
Published in final edited form as: Biochem J. 2013 Oct 1; 455(1): 95–106. doi: 10.1042/BJ20121755
PMCID:
PMC4285712
AbstractArticlePDF–1.5M
19.
A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer
Matthew Gallon, Thomas Clairfeuille, Florian Steinberg, Caroline Mas, Rajesh Ghai, Richard B. Sessions, Rohan D. Teasdale, Brett M. Collins, Peter J. Cullen
Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): E3604–E3613. Published online 2014 Aug 18. doi: 10.1073/pnas.1410552111
PMCID:
PMC4156734
AbstractArticlePDF–3.0M
20.
SNX27 regulation of GIRK channels in VTA dopamine neurons attenuates in vivo cocaine response
Michaelanne B. Munoz, Paul A. Slesinger
Neuron. Author manuscript; available in PMC 2015 May 7.
Published in final edited form as: Neuron. 2014 May 7; 82(3): 659–669. doi: 10.1016/j.neuron.2014.03.011
PMCID:
PMC4141045
AbstractArticlePDF–2.3M

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