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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow
Yuji Kamioka, Yoshihiro Ueda, Naoyuki Kondo, Keizo Tokuhiro, Yoshiki Ikeda, Wolfgang Bergmeier, Tatsuo Kinashi
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112580. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112580
PMCID:
PMC10592472
AbstractArticlePDF–2.2M
4.
The critical role of Rap1-GAPs Rasa3 and Sipa1 in T cells for pulmonary transit and egress from the lymph nodes
Shunsuke Horitani, Yoshihiro Ueda, Yuji Kamioka, Naoyuki Kondo, Yoshiki Ikeda, Makoto Naganuma, Tatsuo Kinashi
Front Immunol. 2023; 14: 1234747. Published online 2023 Jul 20. doi: 10.3389/fimmu.2023.1234747
PMCID:
PMC10399222
AbstractArticlePDF–8.9M
5.
Rasa3 Regulates Stage-Specific Cell Cycle Progression In Murine Erythropoiesis
Elena C. Brindley, Julien Papoin, Lauren Kennedy, Raymond F. Robledo, Steven L. Ciciotte, Theodosia A. Kalfa, Luanne L. Peters, Lionel Blanc
Blood Cells Mol Dis. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: Blood Cells Mol Dis. 2021 Mar; 87: 102524. Published online 2020 Dec 13. doi: 10.1016/j.bcmd.2020.102524
PMCID:
PMC7856249
AbstractArticlePDF–1.3M
6.
Differential effects of RASA3 mutations on hematopoiesis are profoundly influenced by genetic background and molecular variant
Raymond F. Robledo, Steven L. Ciciotte, Joel H. Graber, Yue Zhao, Amy J. Lambert, Babette Gwynn, Nathaniel J. Maki, Elena C. Brindley, Emily Hartman, Lionel Blanc, Luanne L. Peters
PLoS Genet. 2020 Dec; 16(12): e1008857. Published online 2020 Dec 28. doi: 10.1371/journal.pgen.1008857
PMCID:
PMC7793307
AbstractArticlePDF–3.4M
7.
RAS P21 Protein Activator 3 (RASA3) specifically promotes pathogenic T helper 17 cell generation by repressing T helper 2-biased programs
Bing Wu, Song Zhang, Zengli Guo, Gang Wang, Ge Zhang, Ling Xie, Jitong Lou, Xian Chen, Di Wu, Wolfgang Bergmeier, Junnian Zheng, Yisong Y. Wan
Immunity. Author manuscript; available in PMC 2019 Nov 20.
Published in final edited form as: Immunity. 2018 Nov 20; 49(5): 886–898.e5. Published online 2018 Nov 13. doi: 10.1016/j.immuni.2018.09.004
PMCID:
PMC6249088
ArticlePDF–1.1M
8.
Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model scat
Emily S. Hartman, Elena C. Brindley, Julien Papoin, Steven L. Ciciotte, Yue Zhao, Luanne L. Peters, Lionel Blanc
Front Physiol. 2018; 9: 689. Published online 2018 Jun 5. doi: 10.3389/fphys.2018.00689
PMCID:
PMC5996270
AbstractArticlePDF–2.5M
9.
Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism
Patricia Molina-Ortiz, Tanguy Orban, Maud Martin, Audrey Habets, Franck Dequiedt, Stéphane Schurmans
PLoS Genet. 2018 Jan; 14(1): e1007195. Published online 2018 Jan 30. doi: 10.1371/journal.pgen.1007195
PMCID:
PMC5806903
AbstractArticlePDF–13M
10.
The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling
Anthony M. Battram, Tom N. Durrant, Ejaife O. Agbani, Kate J. Heesom, David S. Paul, Raymond Piatt, Alastair W. Poole, Peter J. Cullen, Wolfgang Bergmeier, Samantha F. Moore, Ingeborg Hers
J Biol Chem. 2017 Feb 3; 292(5): 1691–1704. Published online 2016 Nov 30. doi: 10.1074/jbc.M116.746867
PMCID:
PMC5290945
AbstractArticlePDF–3.4M
11.
The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft
Immunity. Author manuscript; available in PMC 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017
PMCID:
PMC4618086
AbstractArticlePDF–2.2M
12.
RASA3 is a critical inhibitor of RAP1-dependent platelet activation
Lucia Stefanini, David S. Paul, Raymond F. Robledo, E. Ricky Chan, Todd M. Getz, Robert A. Campbell, Daniel O. Kechele, Caterina Casari, Raymond Piatt, Kathleen M. Caron, Nigel Mackman, Andrew S. Weyrich, Matthew C. Parrott, Yacine Boulaftali, Mark D. Adams, Luanne L. Peters, Wolfgang Bergmeier
J Clin Invest. 2015 Apr 1; 125(4): 1419–1432. Published online 2015 Feb 23. doi: 10.1172/JCI77993
PMCID:
PMC4396462
AbstractArticlePDF–3.5M
13.
Rasa3 Controls Megakaryocyte Rap1 Activation, Integrin Signaling and Differentiation into Proplatelet
Patricia Molina-Ortiz, Séléna Polizzi, Eve Ramery, Stéphanie Gayral, Céline Delierneux, Cécile Oury, Shintaro Iwashita, Stéphane Schurmans
PLoS Genet. 2014 Jun; 10(6): e1004420. Published online 2014 Jun 26. doi: 10.1371/journal.pgen.1004420
PMCID:
PMC4072513
AbstractArticlePDF–7.8M
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
15.
The scat mouse model highlights RASA3, a GTPase activating protein, as a key regulator of vertebrate erythropoiesis and megakaryopoiesis
Luanne L. Peters, Barry H. Paw, Lionel Blanc
Small GTPases. 2013 Jan 1; 4(1): 47–50. doi: 10.4161/sgtp.23013
PMCID:
PMC3620102
AbstractArticlePDF–682K
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis
Lionel Blanc, Steven L. Ciciotte, Babette Gwynn, Gordon J. Hildick-Smith, Eric L. Pierce, Kathleen A. Soltis, Jeffrey D. Cooney, Barry H. Paw, Luanne L. Peters
Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30): 12099–12104. Published online 2012 Jul 6. doi: 10.1073/pnas.1204948109
PMCID:
PMC3409772
AbstractArticlePDF–916K
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Long-Term Potentiation in the CA1 Hippocampus Induced by NR2A Subunit-Containing NMDA Glutamate Receptors Is Mediated by Ras-GRF2/Erk Map Kinase Signaling
Shan-xue Jin, Larry A. Feig
PLoS One. 2010; 5(7): e11732. Published online 2010 Jul 22. doi: 10.1371/journal.pone.0011732
PMCID:
PMC2908693
AbstractArticlePDF–371K
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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