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Items: 1 to 20 of 72

1.
Deletion of Slc9a1 in Cx3cr1+ cells stimulated microglial subcluster CREB1 signaling and microglia-oligodendrocyte crosstalk
Shanshan Song, Helena Oft, Shamseldin Metwally, Satya Paruchuri, John Bielanin, Victoria Fiesler, Chaim Sneiderman, Gary Kohanbash, Dandan Sun
J Neuroinflammation. 2024; 21: 69. Published online 2024 Mar 20. doi: 10.1186/s12974-024-03065-z
PMCID:
PMC10953158
AbstractArticlePDF–8.9M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
4.
Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice
Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II
Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077
PMCID:
PMC10577278
AbstractArticlePDF–1.9M
5.
Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke
Shamseldin Ayman Hassan Metwally, Satya Siri Paruchuri, Lauren Yu, Okan Capuk, Nicholas Pennock, Dandan Sun, Shanshan Song
Int J Mol Sci. 2023 Sep; 24(17): 13289. Published online 2023 Aug 27. doi: 10.3390/ijms241713289
PMCID:
PMC10488118
AbstractArticlePDF–3.0M
6.
Receptor-independent fluid-phase macropinocytosis promotes arterial foam cell formation and atherosclerosis
Hui-Ping Lin, Bhupesh Singla, WonMo Ahn, Pushpankur Ghoshal, Maria Blahove, Mary Cherian-Shaw, Alex Chen, April Haller, David Y. Hui, Kunzhe Dong, Jiliang Zhou, Joseph White, Alexis M. Stranahan, Agnieszka Jasztal, Rudolf Lucas, Brian K. Stansfield, David Fulton, Stefan Chlopicki, Gábor Csányi
Sci Transl Med. Author manuscript; available in PMC 2023 Sep 21.
Published in final edited form as: Sci Transl Med. 2022 Sep 21; 14(663): eadd2376. Published online 2022 Sep 21. doi: 10.1126/scitranslmed.add2376
PMCID:
PMC9645012
AbstractArticlePDF–1.7M
7.
NOX activation in reactive astrocytes regulates astrocytic LCN2 expression and neurodegeneration
Ruijia Liu, Jun Wang, Yang Chen, Jenelle M. Collier, Okan Capuk, Shijie Jin, Ming Sun, Sujan K. Mondal, Theresa L. Whiteside, Donna B. Stolz, Yongjie Yang, Gulnaz Begum
Cell Death Dis. 2022 Apr; 13(4): 371. Published online 2022 Apr 19. doi: 10.1038/s41419-022-04831-8
PMCID:
PMC9018876
AbstractArticlePDF–6.9M
8.
Structure and mechanism of the human NHE1-CHP1 complex
Yanli Dong, Yiwei Gao, Alina Ilie, DuSik Kim, Annie Boucher, Bin Li, Xuejun C. Zhang, John Orlowski, Yan Zhao
Nat Commun. 2021; 12: 3474. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23496-z
PMCID:
PMC8190280
AbstractArticlePDF–4.4M
9.
Phagocytic activity of splenic macrophages is enhanced and accompanied by cytosolic alkalinization in TRPM7 kinase-dead mice
Pavani Beesetty, Jananie Rockwood, Taku Kaitsuka, Tetyana Zhelay, Siham Hourani, Masayuki Matsushita, J. Ashot Kozak
FEBS J. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: FEBS J. 2021 Jun; 288(11): 3585–3601. Published online 2021 Jan 6. doi: 10.1111/febs.15683
PMCID:
PMC8184566
AbstractArticlePDF–1.7M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells
Md Nabiul Hasan, Lanxin Luo, Dawei Ding, Shanshan Song, Mohammad Iqbal H. Bhuiyan, Ruijia Liu, Lesley M. Foley, Xiudong Guan, Gary Kohanbash, T. Kevin Hitchens, Maria G. Castro, Zhongling Zhang, Dandan Sun
Theranostics. 2021; 11(3): 1295–1309. Published online 2021 Jan 1. doi: 10.7150/thno.50150
PMCID:
PMC7738877
AbstractArticlePDF–3.0M
12.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
13.
Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis
Cong-Lin Liu, Xian Zhang, Jing Liu, Yunzhe Wang, Galina K. Sukhova, Gregory R. Wojtkiewicz, Tianxiao Liu, Rui Tang, Samuel Achilefu, Matthias Nahrendorf, Peter Libby, Junli Guo, Jin-Ying Zhang, Guo-Ping Shi
Nat Commun. 2019; 10: 3978. Published online 2019 Sep 4. doi: 10.1038/s41467-019-11983-3
PMCID:
PMC6726618
AbstractArticlePDF–8.7M
14.
Decreased Neuronal Death in Na+/H+ Exchanger Isoform 1-Null Mice after In Vitro and In Vivo Ischemia
Jing Luo, Hai Chen, Douglas B. Kintner, Gary E. Shull, Dandan Sun
J Neurosci. 2005 Dec 7; 25(49): 11256–11268. doi: 10.1523/JNEUROSCI.3271-05.2005
PMCID:
PMC6725894
AbstractArticlePDF–932K
15.
Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post-stroke function recovery
Shanshan Song, Shaoxia Wang, Victoria M. Pigott, Tong Jiang, Lesley M. Foley, Abhishek Mishra, Rachana Nayak, Wen Zhu, Gulnaz Begum, Yejie Shi, Karen E. Carney, T. Kevin Hitchens, Gary E. Shull, Dandan Sun
Glia. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Glia. 2018 Nov; 66(11): 2279–2298. Published online 2018 Jul 25. doi: 10.1002/glia.23456
PMCID:
PMC6430713
AbstractArticlePDF–1.9M
16.
Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy
Xiudong Guan, Md Nabiul Hasan, Gulnaz Begum, Gary Kohanbash, Karen E. Carney, Victoria M. Pigott, Anders I. Persson, Maria G. Castro, Wang Jia, Dandan Sun
Cell Death Dis. 2018 Oct; 9(10): 1010. Published online 2018 Sep 27. doi: 10.1038/s41419-018-1062-3
PMCID:
PMC6160445
AbstractArticlePDF–4.3M
17.
Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke
Gulnaz Begum, Shanshan Song, Shaoxia Wang, Hanshu Zhao, Mohammad Iqbal H. Bhuiyan, Eric Li, Rachel Nepomuceno, Qing Ye, Ming Sun, Michael Joseph Calderon, Donna B. Stolz, Claudette St. Croix, Simon C. Watkins, Yinhuai Chen, Pingnian He, Gary E. Shull, Dandan Sun
Glia. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Glia. 2018 Jan; 66(1): 126–144. Published online 2017 Sep 19. doi: 10.1002/glia.23232
PMCID:
PMC5705024
AbstractArticlePDF–1.2M
18.
Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 Cells
Yogesh Singh, Yuetao Zhou, Xiaolong Shi, Shaqiu Zhang, Anja T. Umbach, Madhuri S. Salker, Karl S. Lang, Florian Lang
J Biol Chem. 2016 Nov 4; 291(45): 23662–23671. Published online 2016 Sep 14. doi: 10.1074/jbc.M116.730259
PMCID:
PMC5095419
AbstractArticlePDF–2.0M
19.
Role of Rho kinase and Na+/H+ exchange in hypoxia‐induced pulmonary arterial smooth muscle cell proliferation and migration
Jasmine Walker, Clark Undem, Xin Yun, Julie Lade, Haiyang Jiang, Larissa A. Shimoda
Physiol Rep. 2016 Mar; 4(6): e12702. Published online 2016 Mar 23. doi: 10.14814/phy2.12702
PMCID:
PMC4814889
AbstractArticlePDF–719K
20.
PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2–ERK1/2–p90RSK and AKT signaling pathways
Ditte L. Clement, Sabine Mally, Christian Stock, Mette Lethan, Peter Satir, Albrecht Schwab, Stine F. Pedersen, Søren T. Christensen
J Cell Sci. 2013 Feb 15; 126(4): 953–965. doi: 10.1242/jcs.116426
PMCID:
PMC4481637
AbstractArticle

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