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Select item 117253021.

Metabolic regulation of homologous recombination repair by MRE11 lactylation

Yuping Chen, Jinhuan Wu, Linhui Zhai, Tingting Zhang, Hui Yin, Huanyao Gao, Fei Zhao, Zhe Wang, Xiaoning Yang, Mingpeng Jin, Bingsong Huang, Xin Ding, Rui Li, Jie Yang, Yiming He, Qianwen Wang, Weibin Wang, Jake A. Kloeber, Yunxuan Li, Bingbing Hao, Yuanyuan Zhang, Jiadong Wang, Minjia Tan, Ke Li, Ping Wang, Zhenkun Lou, Jian Yuan

Cell. Author manuscript; available in PMC 2025 Jan 18.

Published in final edited form as: Cell. 2024 Jan 18; 187(2): 294–311.e21. Published online 2023 Dec 20. doi: 10.1016/j.cell.2023.11.022

PMCID:: PMC11725302

Article PDF–3.1M

Select item 114472562.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Article PDF–2.8M

Select item 111155973.

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

Zita Nagy, Anne Riss, Sally Fujiyama, Arnaud Krebs, Meritxell Orpinell, Pascal Jansen, Adrian Cohen, Henk G. Stunnenberg, Shigeaki Kato, Làszlò Tora

Cell Mol Life Sci. 2010 Feb; 67(4): 611–628. Published online 2009 Nov 21. doi: 10.1007/s00018-009-0199-8

PMCID:: PMC11115597

Article PDF–816K

Select item 110911184.

GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity

Yang Han, Hongling Zhao, Gang Li, Jin Jia, Hejiang Guo, Jinpeng Tan, Xingyao Sun, Saiyu Li, Qian Ran, Chenjun Bai, Yongqing Gu, ZhongJun Li, Hua Guan, Shanshan Gao, Ping-Kun Zhou

Br J Cancer. 2024 Jun 1; 130(10): 1621–1634. Published online 2024 Apr 4. doi: 10.1038/s41416-024-02636-4

PMCID:: PMC11091118

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Select item 105918365.

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113099. Published online 2023 Sep 8. doi: 10.1016/j.celrep.2023.113099

PMCID:: PMC10591836

Article PDF–2.6M

Select item 103241606.

Aberrant KAT2A accumulations render TRIM22-low melanoma sensitive to Notch1 inhibitors via epigenetic reprogramming

Xiaoli Gu, Wei Min, Yibin Zeng, Ni Fan, Qihong Qian

J Transl Med. 2023; 21: 443. Published online 2023 Jul 6. doi: 10.1186/s12967-023-04305-1

PMCID:: PMC10324160

Article PDF–11M

Select item 102806147.

Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis

Wei Lu, Li Zhang, Kun Ji, Ling Ding, Guofeng Wu

Clin Exp Dent Res. 2023 Jun; 9(3): 464–471. Published online 2023 Apr 6. doi: 10.1002/cre2.695

PMCID:: PMC10280614

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Select item 96021698.

KAT2A/E2F1 Promotes Cell Proliferation and Migration via Upregulating the Expression of UBE2C in Pan-Cancer

Shudai Lin, Li Qiu, Keying Liang, Haibo Zhang, Mingjian Xian, Zixi Chen, Jinfen Wei, Shuying Fu, Xiaocheng Gong, Ke Ding, Zihao Zhang, Bowen Hu, Xiquan Zhang, Yuyou Duan, Hongli Du

Genes (Basel) 2022 Oct; 13(10): 1817. Published online 2022 Oct 8. doi: 10.3390/genes13101817

PMCID:: PMC9602169

Article PDF–5.1M

Select item 94540909.

The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A

Ananya Anmangandla, Yuxiang Ren, Qin Fu, Sheng Zhang, Hening Lin

Biochemistry. 2022 Sep 6; 61(17): 1874–1882. Published online 2022 Aug 22. doi: 10.1021/acs.biochem.2c00308

PMCID:: PMC9454090

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Select item 935766210.

H1.0 induces paclitaxel‐resistance genes expression in ovarian cancer cells by recruiting GCN5 and androgen receptor

Abhidha Kohli, Shang‐Lang Huang, Ting‐Chang Chang, Chuck C.‐K. Chao, Nian‐Kang Sun

Cancer Sci. 2022 Aug; 113(8): 2616–2626. Published online 2022 Jun 13. doi: 10.1111/cas.15448

PMCID:: PMC9357662

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Select item 926261411.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

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Select item 917548212.

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression

Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma

BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4

PMCID:: PMC9175482

Article PDF–15M

Select item 911973613.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

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Select item 882889514.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Article PDF–1.7M

Select item 875320715.

KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia

Liliana Arede, Elena Foerner, Selinde Wind, Rashmi Kulkarni, Ana Filipa Domingues, George Giotopoulos, Svenja Kleinwaechter, Maximilian Mollenhauer-Starkl, Holly Davison, Aditya Chandru, Ryan Asby, Ralph Samarista, Shikha Gupta, Dorian Forte, Antonio Curti, Elisabeth Scheer, Brian J. P. Huntly, Laszlo Tora, Cristina Pina

Blood Adv. 2022 Jan 11; 6(1): 165–180. Published online 2022 Jan 7. doi: 10.1182/bloodadvances.2020002842

PMCID:: PMC8753207

Article PDF–2.3M

Select item 869622016.

P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer

Yin‐Wei Cheng, Fa‐Min Zeng, Da‐Jia Li, Shao‐Hong Wang, Jian‐Zhong He, Zhen‐Chang Guo, Ping‐Juan Nie, Zhi‐Yong Wu, Wen‐Qi Shi, Bing Wen, Xiu‐E Xu, Lian‐Di Liao, Zhi‐Mao Li, Jian‐Yi Wu, Jun Zhan, Hong‐Quan Zhang, Zhi‐Jie Chang, Kai Zhang, Li‐Yan Xu, En‐Min Li

Cancer Commun (Lond) 2021 Dec; 41(12): 1398–1416. Published online 2021 Sep 23. doi: 10.1002/cac2.12221

PMCID:: PMC8696220

Article PDF–5.3M

Select item 855721117.

A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus

Youzhou Tang, Xinyu Li, Yafang Wei, Yongchao Sun, Yeyi Yang, Xianming Zhang, Zhihao Gao, Jishi Liu, Quan Zhuang

Cell Death Dis. 2021 Nov; 12(11): 1036. Published online 2021 Oct 30. doi: 10.1038/s41419-021-04323-1

PMCID:: PMC8557211

Article PDF–4.5M

Select item 838659818.

Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation

Changhan Ouyang, Jing Mu, Qiulun Lu, Jian Li, Huaiping Zhu, Qilong Wang, Ming-Hui Zou, Zhonglin Xie

Autophagy. 2020; 16(10): 1753–1770. Published online 2019 Dec 27. doi: 10.1080/15548627.2019.1707488

PMCID:: PMC8386598

Article PDF–8.2M

Select item 835791519.

KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer

Dingheng Lu, Yarong Song, Ying Yu, Decai Wang, Bing Liu, Liang Chen, Xuexiang Li, Yunxue Li, Lulin Cheng, Fang Lv, Pu Zhang, Yifei Xing

Cell Death Dis. 2021 Aug; 12(8): 787. Published online 2021 Aug 12. doi: 10.1038/s41419-021-04077-w

PMCID:: PMC8357915

Article PDF–4.2M

Select item 822039120.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Article PDF–4.4M

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