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Select item 107554981.

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

Chun-Guang Guo, Rui Sun, Xiao Wang, Ye Yuan, Yan Xu, Shihan Li, Xueting Sun, Jue Wang, Xinli Hu, Tiannan Guo, Xiao-Wei Chen, Rui-Ping Xiao, Xiuqin Zhang

Mol Metab. 2024 Jan; 79: 101847. Published online 2023 Nov 30. doi: 10.1016/j.molmet.2023.101847

PMCID:: PMC10755498

Abstract Article PDF–3.6M

Select item 104036402.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 103306083.

Quantitative Proteomic Profiling Identifies Global Protein Network Dynamics in Murine Embryonic Heart Development

Whitney Edwards, Todd M. Greco, Gregory E. Miner, Natalie K. Barker, Laura Herring, Sarah Cohen, Ileana M. Cristea, Frank L. Conlon

Dev Cell. Author manuscript; available in PMC 2024 Jun 19.

Published in final edited form as: Dev Cell. 2023 Jun 19; 58(12): 1087–1105.e4. Published online 2023 May 5. doi: 10.1016/j.devcel.2023.04.011

PMCID:: PMC10330608

Abstract Article PDF–3.6M

Select item 99637164.

Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone

Yuval Yogev, Zamir Shorer, Arie Koifman, Ohad Wormser, Max Drabkin, Daniel Halperin, Vadim Dolgin, Regina Proskorovski-Ohayon, Noam Hadar, Geula Davidov, Hila Nudelman, Raz Zarivach, Ilan Shelef, Yonatan Perez, Ohad S. Birk

Proc Natl Acad Sci U S A. 2023 Feb 14; 120(7): e2217831120. Published online 2023 Feb 6. doi: 10.1073/pnas.2217831120

PMCID:: PMC9963716

Abstract Article PDF–2.9M

Select item 89576085.

Intestinal deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase promotes expansion of the resident stem cell compartment

Alexandria M. Doerfler, Jun Han, Kelsey E. Jarrett, Li Tang, Antrix Jain, Alexander Saltzman, Marco De Giorgi, Marcel Chuecos, Ayrea E. Hurley, Ang Li, Pauline Morand, Claudia Ayala, David R. Goodlett, Anna Malovannaya, James F. Martin, Thomas Q. de Aguiar Vallim, Noah Shroyer, William R. Lagor

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2022 Apr; 42(4): 381–394. Published online 2022 Feb 17. doi: 10.1161/ATVBAHA.122.317320

PMCID:: PMC8957608

Abstract Article PDF–2.2M

Select item 81626866.

PEG3 controls lipogenesis through ACLY

Subash Ghimire, Joomyeong Kim

PLoS One. 2021; 16(5): e0252354. Published online 2021 May 28. doi: 10.1371/journal.pone.0252354

PMCID:: PMC8162686

Abstract Article PDF–2.3M

Select item 79956617.

Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver

Shanshan Zhong, Luxiao Li, Ningning Liang, Lili Zhang, Xiaodong Xu, Shiting Chen, Huiyong Yin

Redox Biol. 2021 May; 41: 101919. Published online 2021 Mar 10. doi: 10.1016/j.redox.2021.101919

PMCID:: PMC7995661

Abstract Article PDF–9.8M

Select item 78877588.

Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector T_reg cells

Wei Su, Nicole M. Chapman, Jun Wei, Hu Zeng, Yogesh Dhungana, Hao Shi, Jordy Saravia, Peipei Zhou, Lingyun Long, Sherri Rankin, KC Anil, Peter Vogel, Hongbo Chi

Cell Metab. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Cell Metab. 2020 Dec 1; 32(6): 996–1011.e7. Published online 2020 Nov 17. doi: 10.1016/j.cmet.2020.10.022

PMCID:: PMC7887758

Abstract Article PDF–2.6M

Select item 77071649.

Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase

Marco De Giorgi, Kelsey E. Jarrett, Jason C. Burton, Alexandria M. Doerfler, Ayrea Hurley, Ang Li, Rachel H. Hsu, Mia Furgurson, Kalyani R. Patel, Jun Han, Christoph H. Borchers, William R. Lagor

J Lipid Res. 2020 Dec; 61(12): 1675–1686. Published online 2020 Oct 27. doi: 10.1194/jlr.RA120001006

PMCID:: PMC7707164

Abstract Article PDF–2.1M

Select item 768101210.

GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism

Lisha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang

J Biol Chem. 2020 Nov 20; 295(47): 15988–16001. Published online 2020 Sep 10. doi: 10.1074/jbc.RA120.015020

PMCID:: PMC7681012

Abstract Article PDF–3.6M

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 710685212.

Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid

Paul P. Van Veldhoven, Evelyn de Schryver, Stephen G. Young, An Zwijsen, Marc Fransen, Marc Espeel, Myriam Baes, Elke Van Ael

Front Cell Dev Biol. 2020; 8: 144. Published online 2020 Mar 24. doi: 10.3389/fcell.2020.00144

PMCID:: PMC7106852

Abstract Article PDF–4.7M

Select item 667031813.

Disruption of Krox20–Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution

Anne Desmazières, Laurence Decker, Jean-Michel Vallat, Patrick Charnay, Pascale Gilardi-Hebenstreit

J Neurosci. 2008 Jun 4; 28(23): 5891–5900. doi: 10.1523/JNEUROSCI.5187-07.2008

PMCID:: PMC6670318

Abstract Article PDF–664K

Select item 642087914.

Metabolic heterogeneity underlies reciprocal fates of T_H17 cell stemness and plasticity

Peer W F Karmaus, Xiang Chen, Seon Ah Lim, Andrés A Herrada, Thanh-Long M Nguyen, Beisi Xu, Yogesh Dhungana, Sherri Rankin, Wenan Chen, Celeste Rosencrance, Kai Yang, Yiping Fan, Yong Cheng, John Easton, Geoffrey Neale, Peter Vogel, Hongbo Chi

Nature. Author manuscript; available in PMC 2019 Jun 19.

Published in final edited form as: Nature. 2019 Jan; 565(7737): 101–105. Published online 2018 Dec 19. doi: 10.1038/s41586-018-0806-7

PMCID:: PMC6420879

Abstract Article PDF–2.7M

Select item 640283415.

Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice

Youngah Jo, Jason S Hamilton, Seonghwan Hwang, Kristina Garland, Gennipher A Smith, Shan Su, Iris Fuentes, Sudha Neelam, Bonne M Thompson, Jeffrey G McDonald, Russell A DeBose-Boyd

eLife. 2019; 8: e44396. Published online 2019 Feb 20. doi: 10.7554/eLife.44396

PMCID:: PMC6402834

Abstract Article PDF–3.3M

Select item 605365716.

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis

Hidetoshi Tsushima, Yuning J. Tang, Vijitha Puviindran, Shu-Hsuan Claire Hsu, Puviindran Nadesan, Chunying Yu, Hongyuan Zhang, Anthony J. Mirando, Matthew J. Hilton, Benjamin A. Alman

Development. 2018 Jul 1; 145(13): dev162396. Published online 2018 Jul 9. doi: 10.1242/dev.162396

PMCID:: PMC6053657

Abstract Article

Select item 600407117.

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

Minchul Kim, Hagen Wende, Jan Walcher, Johannes Kühnemund, Cyril Cheret, Stefan Kempa, Erik McShane, Matthias Selbach, Gary R. Lewin, Carmen Birchmeier

Genes Dev. 2018 May 1; 32(9-10): 645–657. doi: 10.1101/gad.310490.117

Correction in:: Genes Dev. 2018 Aug 1; 32(15-16): 1101.

PMCID:: PMC6004071

Abstract Article PDF–9.0M

Select item 582402418.

PPARα-Target Gene Expression Requires TIS21^/BTG2 Gene in Liver of the C57BL/6 Mice under Fasting Condition

Allen Eugene Hong, Min Sook Ryu, Seung Jun Kim, Seung Yong Hwang, In Kyoung Lim

Mol Cells. 2018 Feb 28; 41(2): 140–149. Published online 2018 Jan 29. doi: 10.14348/molcells.2018.2257

PMCID:: PMC5824024

Abstract Article PDF–3.2M

Select item 575227219.

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Marzia Scortegagna, Annabel Berthon, Nikolaos Settas, Andreas Giannakou, Guillermina Garcia, Jian-Liang Li, Brian James, Robert C. Liddington, José G. Vilches-Moure, Constantine A. Stratakis, Ze’ev A. Ronai

JCI Insight. 2017 Dec 7; 2(23): e97128. Published online 2017 Dec 7. doi: 10.1172/jci.insight.97128

PMCID:: PMC5752272

Abstract Article PDF–9.0M

Select item 569636920.

Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice

Seung-Wook Shin, Edgar John Vogt, Maria Jimenez-Movilla, Boris Baibakov, Jurrien Dean

Nat Commun. 2017; 8: 1643. Published online 2017 Nov 21. doi: 10.1038/s41467-017-01387-6

PMCID:: PMC5696369

Abstract Article PDF–5.1M

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