PMC Links for GEO Profiles (Select 126242769) - PMC

Yuri Mizuno, Nona Abolhassani, Guianfranco Mazzei, Kunihiko Sakumi, Takashi Saito, Takaomi C. Saido, Toshiharu Ninomiya, Toru Iwaki, Ryo Yamasaki, Jun-ichi Kira, Yusaku Nakabeppu

Oxid Med Cell Longev. 2021; 2021: 8635088. Published online 2021 Dec 21. doi: 10.1155/2021/8635088

Correction in:: Oxid Med Cell Longev. 2023; 2023: 9794081.

PMCID:: PMC8714343

Abstract Article PDF–4.6M

Select item 83730694.

Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover

Sunbok Jang, Matthew A Schaich, Cindy Khuu, Brittani L Schnable, Chandrima Majumdar, Simon C Watkins, Sheila S David, Bennett Van Houten

Nucleic Acids Res. 2021 Aug 20; 49(14): 8177–8188. Published online 2021 Jul 7. doi: 10.1093/nar/gkab591

PMCID:: PMC8373069

Abstract Article PDF–3.9M

Select item 82665925.

Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer

Teruya Nakamura, Kohtaro Okabe, Shogo Hirayama, Mami Chirifu, Shinji Ikemizu, Hiroshi Morioka, Yusaku Nakabeppu, Yuriko Yamagata

Nucleic Acids Res. 2021 Jul 9; 49(12): 7154–7163. Published online 2021 Jun 18. doi: 10.1093/nar/gkab492

PMCID:: PMC8266592

Abstract Article PDF–3.5M

Select item 78789186.

MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model

Hiroki Sakamoto, Koji Miyanishi, Shingo Tanaka, Ryo Ito, Kota Hamaguchi, Akira Sakurada, Masanori Sato, Tomohiro Kubo, Takahiro Osuga, Kazuyuki Murase, Kohichi Takada, Yusaku Nakabeppu, Masayoshi Kobune, Junji Kato

Sci Rep. 2021; 11: 3599. Published online 2021 Feb 11. doi: 10.1038/s41598-021-83138-8

PMCID:: PMC7878918

Abstract Article PDF–5.4M

Select item 76036277.

MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model

Qingmin Sun, Jingwen Chen, Lizhi Xu, Jiaqi Kang, Xin Wu, Yan Ren, Yusaku Nakabeppu, Yaping Wang

Oxid Med Cell Longev. 2020; 2020: 4828256. Published online 2020 Oct 16. doi: 10.1155/2020/4828256

PMCID:: PMC7603627

Abstract Article PDF–2.5M

Select item 70762188.

The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites

Alan G. Raetz, Douglas M. Banda, Xiaoyan Ma, Gege Xu, Anisha N. Rajavel, Paige L. McKibbin, Carlito B. Lebrilla, Sheila S. David

J Biol Chem. 2020 Mar 13; 295(11): 3692–3707. Published online 2020 Jan 30. doi: 10.1074/jbc.RA119.010497

PMCID:: PMC7076218

Abstract Article PDF–3.1M

Select item 64511179.

Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant

Shane R Nelson, Scott D Kathe, Thomas S Hilzinger, April M Averill, David M Warshaw, Susan S Wallace, Andrea J Lee

Nucleic Acids Res. 2019 Apr 8; 47(6): 3058–3071. Published online 2019 Jan 30. doi: 10.1093/nar/gkz045

PMCID:: PMC6451117

Abstract Article PDF–2.6M

Select item 606178710.

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

Johanna H K Kauppila, Nina A Bonekamp, Arnaud Mourier, Marita A Isokallio, Alexandra Just, Timo E S Kauppila, James B Stewart, Nils-Göran Larsson

Nucleic Acids Res. 2018 Jul 27; 46(13): 6642–6669. Published online 2018 May 31. doi: 10.1093/nar/gky456

PMCID:: PMC6061787

Abstract Article PDF–3.0M

Select item 514701611.

Perturbed hematopoiesis in mice lacking ATMIN

Fernando Anjos-Afonso, Joanna I. Loizou, Amy Bradburn, Nnennaya Kanu, Sukhveer Purewal, Clive Da Costa, Dominique Bonnet, Axel Behrens

Blood. 2016 Oct 20; 128(16): 2017–2021. Prepublished online 2016 Aug 31. doi: 10.1182/blood-2015-09-672980

PMCID:: PMC5147016

Abstract Article

Select item 503375212.

MUTYH promotes oxidative microglial activation and inherited retinal degeneration

Shunji Nakatake, Yusuke Murakami, Yasuhiro Ikeda, Noriko Morioka, Takashi Tachibana, Kohta Fujiwara, Noriko Yoshida, Shoji Notomi, Toshio Hisatomi, Shigeo Yoshida, Tatsuro Ishibashi, Yusaku Nakabeppu, Koh-Hei Sonoda

JCI Insight. 2016 Sep 22; 1(15): e87781. Published online 2016 Sep 22. doi: 10.1172/jci.insight.87781

PMCID:: PMC5033752

Abstract Article PDF–2.4M

Select item 463731313.

The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis

Francesca Grasso, Serena Di Meo, Gabriele De Luca, Luca Pasquini, Stefania Rossi, Monica Boirivant, Mauro Biffoni, Margherita Bignami, Emma Di Carlo

Oncotarget. 2015 Aug 14; 6(23): 19671–19684. Published online 2015 Jun 18. doi: 10.18632/oncotarget.4284

PMCID:: PMC4637313

Abstract Article PDF–7.4M

Select item 448069414.

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation

Francesca Grasso, Vitalba Ruggieri, Gabriele De Luca, Paola Leopardi, Maria Teresa Mancuso, Ida Casorelli, Pietro Pichierri, Peter Karran, Margherita Bignami

Oncotarget. 2015 Apr 10; 6(10): 7481–7492. Published online 2014 Dec 2. doi: 10.18632/oncotarget.3037

PMCID:: PMC4480694

Abstract Article PDF–3.8M

Select item 446122715.

Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage

Bor-Jang Hwang, Gouli Shi, A-Lien Lu

DNA Repair (Amst) Author manuscript; available in PMC 2015 Jun 9.

Published in final edited form as: DNA Repair (Amst). 2014 Jan; 13: 10–21. Published online 2013 Dec 4. doi: 10.1016/j.dnarep.2013.10.011

PMCID:: PMC4461227

Abstract Article PDF–1021K

Select item 445817416.

Association of the Rad9-Rad1-Hus1 Checkpoint Clamp with MYH DNA Glycosylase and DNA

Bor-Jang Hwang, Jin Jin, Randall Gunther, Amrita Madabushi, Guoli Shi, Gerald M. Wilson, A-Lien Lu

DNA Repair (Amst) Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: DNA Repair (Amst). 2015 Jul; 31: 80–90. Published online 2015 May 16. doi: 10.1016/j.dnarep.2015.05.004

PMCID:: PMC4458174

Abstract Article PDF–1.8M

Select item 414722617.

Abnormality in Wnt Signaling is Causatively Associated with Oxidative Stress-Induced Intestinal Tumorigenesis in MUTYH-Null Mice

Takuro Isoda, Yoshimichi Nakatsu, Kazumi Yamauchi, Jingshu Piao, Takashi Yao, Hiroshi Honda, Yusaku Nakabeppu, Teruhisa Tsuzuki

Int J Biol Sci. 2014; 10(8): 940–947. Published online 2014 Aug 23. doi: 10.7150/ijbs.9241

PMCID:: PMC4147226

Abstract Article PDF–917K

Select item 398673018.

8-oxoguanine causes spontaneous de novo germline mutations in mice

Mizuki Ohno, Kunihiko Sakumi, Ryutaro Fukumura, Masato Furuichi, Yuki Iwasaki, Masaaki Hokama, Toshimichi Ikemura, Teruhisa Tsuzuki, Yoichi Gondo, Yusaku Nakabeppu

Sci Rep. 2014; 4: 4689. Published online 2014 Apr 15. doi: 10.1038/srep04689

PMCID:: PMC3986730

Abstract Article PDF–1.8M

Select item 385774119.

Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions

Paz J. Luncsford, Brittney A. Manvilla, Dimeka N. Patterson, Shuja S. Malik, Jin Jin, Bor-Jang Hwang, Randall Gunther, Snigdha Kalvakolanu, Leonora J. Lipinski, Weirong Yuan, Wuyuan Lu, Alexander C. Drohat, A-Lien Lu-Chang, Eric A. Toth

DNA Repair (Amst) Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: DNA Repair (Amst). 2013 Dec; 12(12): 10.1016/j.dnarep.2013.09.007. Published online 2013 Oct 24. doi: 10.1016/j.dnarep.2013.09.007

PMCID:: PMC3857741

Abstract Article PDF–2.8M

Select item 362760220.

Understanding the role of the Q338H MUTYH variant in oxidative damage repair

Eleonora Turco, Ilenia Ventura, Anna Minoprio, Maria Teresa Russo, Paola Torreri, Paolo Degan, Sara Molatore, Guglielmina Nadia Ranzani, Margherita Bignami, Filomena Mazzei

Nucleic Acids Res. 2013 Apr; 41(7): 4093–4103. Published online 2013 Mar 4. doi: 10.1093/nar/gkt130

PMCID:: PMC3627602

Abstract Article PDF–1.8M

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