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Items: 1 to 20 of 69

1.
NF-κB Activator 1 downregulation in macrophages activates STAT3 to promote adenoma-adenocarcinoma transition and immunosuppression in colorectal cancer
Shunyi Wang, Yihe Kuai, Simin Lin, Li Li, Quliang Gu, Xiaohan Zhang, Xiaoming Li, Yajun He, Sishuo Chen, Xiaoru Xia, Zhang Ruan, Caixia Lin, Yi Ding, Qianqian Zhang, Cuiling Qi, Jiangchao Li, Xiaodong He, Janak L. Pathak, Weijie Zhou, Side Liu, Lijing Wang, Lingyun Zheng
BMC Med. 2023; 21: 115. Published online 2023 Mar 29. doi: 10.1186/s12916-023-02791-0
PMCID:
PMC10053426
AbstractArticlePDF–13M
2.
The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis
Rami Bechara, Nilesh Amatya, Rachel D. Bailey, Yang Li, Felix EY Aggor, De-Dong Li, Chetan V. Jawale, Bianca M. Coleman, Ning Dai, Nandan S. Gokhale, Tiffany C. Taylor, Stacy M. Horner, Amanda C. Poholek, Anita Bansal, Partha S. Biswas, Sarah L. Gaffen
Sci Immunol. Author manuscript; available in PMC 2022 Jan 2.
Published in final edited form as: Sci Immunol. 2021 Jul 2; 6(61): eabd1287. doi: 10.1126/sciimmunol.abd1287
PMCID:
PMC8404281
AbstractArticlePDF–2.5M
3.
ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway
Xiaoyuan Lin, Beibei Fu, Songna Yin, Zhifeng Li, Huawen Liu, Haiwei Zhang, Na Xing, Yu Wang, Weiwei Xue, Yan Xiong, Shanfu Zhang, Qingting Zhao, Shiyao Xu, Jing Zhang, Peihui Wang, Weiqi Nian, Xingsheng Wang, Haibo Wu
iScience. 2021 Apr 23; 24(4): 102293. Published online 2021 Mar 9. doi: 10.1016/j.isci.2021.102293
PMCID:
PMC7942160
AbstractArticlePDF–3.4M
4.
IL-10 Dampens an IL-17–Mediated Periodontitis-Associated Inflammatory Network
Lu Sun, Mustafa Girnary, Lufei Wang, Yizu Jiao, Erliang Zeng, Kyle Mercer, Jinmei Zhang, Julie T. Marchesan, Ning Yu, Kevin Moss, Yu L. Lei, Steven Offenbacher, Shaoping Zhang
J Immunol. Author manuscript; available in PMC 2021 Apr 15.
Published in final edited form as: J Immunol. 2020 Apr 15; 204(8): 2177–2191. Published online 2020 Mar 13. doi: 10.4049/jimmunol.1900532
PMCID:
PMC7840149
AbstractArticlePDF–1.3M
5.
TRAF3IP2 mediates obesity-associated vascular insulin resistance and dysfunction in male mice
Zachary I. Grunewald, Francisco I. Ramirez-Perez, Makenzie L. Woodford, Mariana Morales-Quinones, Salvador Mejia, Camila Manrique-Acevedo, Ulrich Siebenlist, Luis A. Martinez-Lemus, Bysani Chandrasekar, Jaume Padilla
Hypertension. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Hypertension. 2020 Oct; 76(4): 1319–1329. Published online 2020 Aug 24. doi: 10.1161/HYPERTENSIONAHA.120.15262
PMCID:
PMC7484238
AbstractArticlePDF–2.0M
6.
An IL-17F.S65L knockin mouse reveals similarities and differences in IL-17F function in oral candidiasis: A new tool to understand IL-17F
Chunsheng Zhou, Leticia Monin, Rachael Gordon, Felix E.Y. Aggor, Rami Bechara, Tara N. Edwards, Daniel H. Kaplan, Sebastien Gingras, Sarah L. Gaffen
J Immunol. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: J Immunol. 2020 Aug 1; 205(3): 720–730. Published online 2020 Jun 29. doi: 10.4049/jimmunol.2000394
PMCID:
PMC7369233
AbstractArticlePDF–1.3M
7.
IL-20-receptor signaling delimits IL-17 production in psoriatic inflammation
Hye-Lin Ha, Hongshan Wang, Estefania Claudio, Wanhu Tang, Ulrich Siebenlist
J Invest Dermatol. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: J Invest Dermatol. 2020 Jan; 140(1): 143–151.e3. Published online 2019 Jun 26. doi: 10.1016/j.jid.2019.06.127
PMCID:
PMC6926146
AbstractArticlePDF–1.6M
8.
IL-25 orchestrates activation of Thelper cells via conventional dendritic cells in tissue to exacerbate chronic HDM-induced asthma pathology
Estefania Claudio, Hongshan Wang, Olena Kamenyeva, Wanhu Tang, Hye-lin Ha, Ulrich Siebenlist
J Immunol. Author manuscript; available in PMC 2020 Oct 15.
Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2319–2327. Published online 2019 Sep 11. doi: 10.4049/jimmunol.1900254
PMCID:
PMC6783368
AbstractArticlePDF–2.4M
9.
TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart
Nitin A. Das, Andrea J. Carpenter, Tadashi Yoshida, Senthil A. Kumar, Sandeep Gautam, Ricardo Mostany, Reza Izadpanah, Ashok Kumar, Srinivas Mummidi, Ulrich Siebenlist, Bysani Chandrasekar
J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Sep 9.
Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 107–123. Published online 2018 Jul 5. doi: 10.1016/j.yjmcc.2018.07.003
PMCID:
PMC6732793
AbstractArticlePDF–3.2M
10.
Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration
Sarah I. Lindstrom, Sigrun Sigurdardottir, Thomas E. Zapadka, Jie Tang, Haitao Liu, Brooklyn E. Taylor, Dawn G. Smith, Chieh A. Lee, John DeAngelis, Timothy S. Kern, Patricia R. Taylor
J Diabetes Complications. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: J Diabetes Complications. 2019 Sep; 33(9): 668–674. Published online 2019 May 29. doi: 10.1016/j.jdiacomp.2019.05.016
PMCID:
PMC6690768
AbstractArticlePDF–987K
11.
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
Saikat Majumder, Nilesh Amatya, Shankar Revu, Chetan V Jawale, Dongwen Wu, Natalie Rittenhouse, Ashley Menk, Saran Kupul, Fang Du, Itay Raphael, Amrita Bhattacharjee, Ulrich Siebenlist, Timothy W Hand, Greg M Delgoffe, Amanda C Poholek, Sarah L Gaffen, Partha S Biswas, Mandy J McGeachy
Nat Immunol. Author manuscript; available in PMC 2019 May 15.
Published in final edited form as: Nat Immunol. 2019 May; 20(5): 534–545. Published online 2019 Apr 8. doi: 10.1038/s41590-019-0367-4
PMCID:
PMC6519710
AbstractArticlePDF–1.2M
12.
IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility
Katarzyna Bulek, Xing Chen, Vandy Parron, Aparna Sundaram, Tomasz Herjan, Suidong Ouyang, Caini Liu, Alana Majors, Jarod Zepp, Ji Gao, Ashok Dongre, Malgorzata Bodaszewska-Lubas, Arnaud Echard, Mark Aronica, Julie Carman, Stavros Garantziotis, Dean Sheppard, Xiaoxia Li
J Immunol. 2019 Mar 1; 202(5): 1540–1548. Published online 2019 Jan 25. doi: 10.4049/jimmunol.1801025
PMCID:
PMC6379809
AbstractArticlePDF–2.0M
13.
IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells
Xing Chen, Gang Cai, Caini Liu, Junjie Zhao, Chunfang Gu, Ling Wu, Thomas A. Hamilton, Cun-jin Zhang, Jennifer Ko, Liang Zhu, Jun Qin, Allison Vidimos, Shlomo Koyfman, Brian R. Gastman, Kim B. Jensen, Xiaoxia Li
J Exp Med. 2019 Jan 7; 216(1): 195–214. doi: 10.1084/jem.20171849
PMCID:
PMC6314525
AbstractArticlePDF–6.9M
14.
IL-17 receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling
Tomasz Herjan, Lingzi Hong, Jodi Bubenik, Katarzyna Bulek, Wen Qian, Caini Liu, Xiao Li, Xing Chen, Hui Yang, Suidong Ouyang, Hao Zhou, Junjie Zhao, Vasu Komireddy, Eric Cockman, Mark Aronica, Kewal Asosingh, Donny D. Licatalosi, Jun Qin, Paul L. Fox, Thomas A. Hamilton, Donna Driscoll, Xiaoxia Li
Nat Immunol. Author manuscript; available in PMC 2018 Sep 21.
Published in final edited form as: Nat Immunol. 2018 Apr; 19(4): 354–365. Published online 2018 Mar 21. doi: 10.1038/s41590-018-0071-9
PMCID:
PMC6082628
AbstractArticlePDF–1.5M
15.
Act1 is a negative regulator in T and B cells via direct inhibition of STAT3
Cun-Jin Zhang, Chenhui Wang, Meiling Jiang, Chunfang Gu, Jianxin Xiao, Xing Chen, Bradley N. Martin, Fangqiang Tang, Erin Yamamoto, Yibo Xian, Han Wang, Fengling Li, R. Balfour Sartor, Howard Smith, M. Elaine Husni, Fu-Dong Shi, Ji Gao, Julie Carman, Ashok Dongre, Susan C. McKarns, Ken Coppieters, Trine N. Jørgensen, Warren J. Leonard, Xiaoxia Li
Nat Commun. 2018; 9: 2745. Published online 2018 Jul 16. doi: 10.1038/s41467-018-04974-3
PMCID:
PMC6048100
AbstractArticlePDF–3.4M
16.
IL-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability
Jacob S. Lee, Cristina M. Tato, Barbara Joyce-Shaikh, Fatih Gulan, Corinne Cayatte, Yi Chen, Wendy M. Blumenschein, Michael Judo, Kevin Chen, Gulesi Ayanoglu, Terrill K. McClanahan, Xiaoxia Li, Daniel J. Cua
Immunity. Author manuscript; available in PMC 2018 Jul 13.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 727–738. Published online 2015 Sep 29. doi: 10.1016/j.immuni.2015.09.003
PMCID:
PMC6044435
AbstractArticlePDF–1.4M
17.
Oral epithelial cells orchestrate innate Type 17 responses to Candida albicans through the virulence factor Candidalysin
Akash H. Verma, Jonathan P. Richardson, Chunsheng Zhou, Bianca M. Coleman, David L. Moyes, Jemima Ho, Anna R. Huppler, Kritika Ramani, Mandy J. McGeachy, Ilgiz A. Mufazalov, Ari Waisman, Lawrence P. Kane, Partha S. Biswas, Bernhard Hube, Julian R. Naglik, Sarah L. Gaffen
Sci Immunol. Author manuscript; available in PMC 2018 Nov 3.
Published in final edited form as: Sci Immunol. 2017 Nov 3; 2(17): eaam8834. doi: 10.1126/sciimmunol.aam8834
PMCID:
PMC5881387
AbstractArticlePDF–1.2M
18.
Interleukin-17B antagonizes interleukin-25-mediated mucosal inflammation
Joseph M. Reynolds, Young-Hee Lee, Yun Shi, Xiaohu Wang, Pornpimon Angkasekwinai, Kalyan C. Nallaparaju, Stephanie Flaherty, Seon Hee Chang, Hiroshi Watarai, Chen Dong
Immunity. Author manuscript; available in PMC 2018 Feb 13.
Published in final edited form as: Immunity. 2015 Apr 21; 42(4): 692–703. Published online 2015 Apr 14. doi: 10.1016/j.immuni.2015.03.008
PMCID:
PMC5811222
AbstractArticlePDF–974K
19.
Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E
Seon Hee Chang, Joseph M. Reynolds, Bhanu P. Pappu, Guangjie Chen, Gustavo J. Martinez, Chen Dong
Immunity. Author manuscript; available in PMC 2018 Feb 6.
Published in final edited form as: Immunity. 2011 Oct 28; 35(4): 611–621. Published online 2011 Oct 6. doi: 10.1016/j.immuni.2011.09.010
PMCID:
PMC5800502
AbstractArticlePDF–833K
20.
IL-17A-induced Plet1 expression contributes to tissue repair and colon tumorigenesis
Jarod A. Zepp, Junjie Zhao, Caini Liu, Katazyna Bulek, Ling Wu, Xing Chen, Yujun Hao, Zhenghe Wang, Xinxin Wang, Wenjun Ouyang, Matthew F. Kalady, Julie Carman, Wen-Pin Yang, Jun Zhu, Clare Blackburn, Yina H. Huang, Thomas Hamilton, Bing Su, Xiaoxia Li
J Immunol. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: J Immunol. 2017 Dec 1; 199(11): 3849–3857. Published online 2017 Oct 25. doi: 10.4049/jimmunol.1601540
PMCID:
PMC5771493
AbstractArticlePDF–953K

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