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Select item 109594151.

FOXL2 interaction with different binding partners regulates the dynamics of ovarian development

Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge

Sci Adv. 2024 Mar 22; 10(12): eadl0788. Published online 2024 Mar 22. doi: 10.1126/sciadv.adl0788

PMCID:: PMC10959415

Abstract Article PDF–4.4M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107038903.

SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability

Antonella Lettieri, Roberto Oleari, Marleen Hester van den Munkhof, Eljo Yvette van Battum, Marieke Geerte Verhagen, Carlotta Tacconi, Marco Spreafico, Alyssa Julia Jennifer Paganoni, Roberta Azzarelli, Valentina Andre’, Federica Amoruso, Luca Palazzolo, Ivano Eberini, Leo Dunkel, Sasha Rose Howard, Alessandro Fantin, Ronald Jeroen Pasterkamp, Anna Cariboni

Nat Commun. 2023; 14: 8097. Published online 2023 Dec 7. doi: 10.1038/s41467-023-43820-z

PMCID:: PMC10703890

Abstract Article PDF–17M

Select item 106541014.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 105057325.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 102944736.

Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease

Ting-Ting Wu, Ying-Ying Zheng, Xiang Ma, Wen-Juan Xiu, Hai-Tao Yang, Xian-Geng Hou, Yi Yang, You Chen, Yi-Tong Ma, Xiang Xie

Cell Commun Signal. 2023; 21: 155. Published online 2023 Jun 27. doi: 10.1186/s12964-023-01061-z

PMCID:: PMC10294473

Abstract Article PDF–6.0M

Select item 100177037.

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions

Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco

Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0

PMCID:: PMC10017703

Abstract Article PDF–16M

Select item 99505158.

Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age

Jorge Lopez-Tello, Amanda N. Sferruzzi-Perri

Front Endocrinol (Lausanne) 2023; 14: 1116770. Published online 2023 Feb 10. doi: 10.3389/fendo.2023.1116770

PMCID:: PMC9950515

Abstract Article PDF–4.2M

Select item 98923039.

Hydroxylation and Lyase Reactions of Steroids Catalyzed by Mouse Cytochrome P450 17A1 (Cyp17a1)

Sung-Gyu Lee, Vitchan Kim, Gyu-Hyeong Lee, Changmin Kim, Eunseo Jeong, F. Peter Guengerich, Donghak Kim

J Inorg Biochem. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: J Inorg Biochem. 2023 Mar; 240: 112085. Published online 2023 Jan 10. doi: 10.1016/j.jinorgbio.2022.112085

PMCID:: PMC9892303

Abstract Article PDF–857K

Select item 965531310.

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate

Nour Abou Nader, Amélie Ménard, Adrien Levasseur, Guillaume St-Jean, Derek Boerboom, Gustavo Zamberlam, Alexandre Boyer

Int J Mol Sci. 2022 Nov; 23(21): 13585. Published online 2022 Nov 5. doi: 10.3390/ijms232113585

PMCID:: PMC9655313

Abstract Article PDF–4.1M

Select item 933804011.

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat

Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1

PMCID:: PMC9338040

Abstract Article PDF–11M

Select item 932773712.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 857083113.

Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain

Philipp Wartenberg, Imre Farkas, Veronika Csillag, William H. Colledge, Erik Hrabovszky, Ulrich Boehm

J Neurosci. 2021 Nov 3; 41(44): 9177–9191. doi: 10.1523/JNEUROSCI.0885-21.2021

PMCID:: PMC8570831

Abstract Article PDF–9.6M

Select item 852019514.

Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse

Christian Secchi, Martina Belli, Tracy N. H. Harrison, Joseph Swift, CheMyong Ko, Antoni J. Duleba, Dwayne Stupack, R. Jeffrey Chang, Shunichi Shimasaki

J Transl Med. 2021; 19: 428. Published online 2021 Oct 15. doi: 10.1186/s12967-021-03103-x

PMCID:: PMC8520195

Abstract Article PDF–2.3M

Select item 851165915.

Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis^†

Shu-Yun Li, Xiaowei Gu, Anna Heinrich, Emily G Hurley, Blanche Capel, Tony DeFalco

Biol Reprod. 2021 Oct; 105(4): 958–975. Published online 2021 May 18. doi: 10.1093/biolre/ioab098

PMCID:: PMC8511659

Abstract Article PDF–2.6M

Select item 829986616.

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility and metabolic homeostasis in female mice

Emmi Rotgers, Barbara Nicol, Karina Rodriguez, Saniya Rattan, Jodi A. Flaws, Humphrey Hung-Chang Yao

FASEB J. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: FASEB J. 2021 Aug; 35(8): e21770. doi: 10.1096/fj.202100304R

PMCID:: PMC8299866

Abstract Article PDF–2.6M

Select item 822474517.

Effect of Differences in the Microbiome of Cyp17a1-Deficient Mice on Atherosclerotic Background

Axel Künstner, Redouane Aherrahrou, Misa Hirose, Petra Bruse, Saleh Mohamed Ibrahim, Hauke Busch, Jeanette Erdmann, Zouhair Aherrahrou

Cells. 2021 Jun; 10(6): 1292. Published online 2021 May 23. doi: 10.3390/cells10061292

PMCID:: PMC8224745

Abstract Article PDF–522K

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 777119019.

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: phenotype and impact on adrenocortical function

Isaac Levy, Eva Szarek, Andrea Gutierrez Maria, Matthew Starrost, Maria De La Luz Sierra, Fabio R. Faucz, Constantine A. Stratakis

Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jan 15.

Published in final edited form as: Mol Cell Endocrinol. 2021 Jan 15; 520: 111071. Published online 2020 Oct 27. doi: 10.1016/j.mce.2020.111071

PMCID:: PMC7771190

Abstract Article PDF–2.5M

Select item 760987620.

Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice

Barbara Nicol, Karina Rodriguez, Humphrey H-C Yao

Biol Reprod. 2020 Nov; 103(5): 966–977. Published online 2020 Aug 25. doi: 10.1093/biolre/ioaa146

PMCID:: PMC7609876

Abstract Article PDF–2.7M

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