PMC Links for GEO Profiles (Select 12654528) - PMC

Henrik Schmidt, Timsse Raj, Thomas J. O'Neill, Andreas Muschaweckh, Florian Giesert, Arlinda Negraschus, Kai P. Hoefig, Gesine Behrens, Lena Esser, Christina Baumann, Regina Feederle, Carlos Plaza-Sirvent, Arie Geerlof, Andreas Gewies, Sophie E. Isay, Jürgen Ruland, Ingo Schmitz, Wolfgang Wurst, Thomas Korn, Daniel Krappmann, Vigo Heissmeyer

Proc Natl Acad Sci U S A. 2023 Nov 28; 120(48): e2309205120. Published online 2023 Nov 21. doi: 10.1073/pnas.2309205120

PMCID:: PMC10691344

Abstract Article PDF–2.0M

Select item 101384564.

Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing

Leonie Wittner, Lukas Wagener, Jakob J. Wiese, Iris Stolzer, Susanne M. Krug, Elisabeth Naschberger, Rene Jackstadt, Rudi Beyaert, Raja Atreya, Anja A. Kühl, Gregor Sturm, Miguel Gonzalez-Acera, Jay V. Patankar, Christoph Becker, Britta Siegmund, Zlatko Trajanoski, Beate Winner, Markus F. Neurath, Michael Schumann, Claudia Günther

Int J Mol Sci. 2023 Apr; 24(8): 7402. Published online 2023 Apr 17. doi: 10.3390/ijms24087402

PMCID:: PMC10138456

Abstract Article PDF–9.1M

Select item 99023455.

TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions

Thomas J. O’Neill, Andreas Gewies, Thomas Seeholzer, Daniel Krappmann

Front Immunol. 2023; 14: 1111398. Published online 2023 Jan 24. doi: 10.3389/fimmu.2023.1111398

PMCID:: PMC9902345

Abstract Article PDF–3.3M

Select item 75897676.

Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury

Roberta Fusco, Rosalba Siracusa, Ramona D’Amico, Marika Cordaro, Tiziana Genovese, Enrico Gugliandolo, Alessio Filippo Peritore, Rosalia Crupi, Rosanna Di Paola, Salvatore Cuzzocrea, Daniela Impellizzeri

Int J Mol Sci. 2020 Oct; 21(20): 7761. Published online 2020 Oct 20. doi: 10.3390/ijms21207761

PMCID:: PMC7589767

Abstract Article PDF–13M

Select item 75175817.

Therapeutic Potential of Targeting Malt1-Dependent TCR Downstream Signaling to Promote the Survival of MHC-Mismatched Allografts

Lerisa Govender, Josip Mikulic, Jean-Christophe Wyss, Olivier Gaide, Margot Thome, Dela Golshayan

Front Immunol. 2020; 11: 576651. Published online 2020 Sep 11. doi: 10.3389/fimmu.2020.576651

PMCID:: PMC7517581

Abstract Article PDF–8.0M

Select item 73328038.

MALT1 targeting suppresses CARD14‐induced psoriatic dermatitis in mice

Elien Van Nuffel, Jens Staal, Griet Baudelet, Mira Haegman, Yasmine Driege, Tino Hochepied, Inna S Afonina, Rudi Beyaert

EMBO Rep. 2020 Jul 3; 21(7): e49237. Published online 2020 Apr 28. doi: 10.15252/embr.201949237

PMCID:: PMC7332803

Abstract Article PDF–1.4M

Select item 68593769.

Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell–Mediated Autoimmunity

Kea Martin, Ratiba Touil, Yeter Kolb, Grozdan Cvijetic, Kiichi Murakami, Laura Israel, Fernanda Duraes, David Buffet, Anton Glück, Satoru Niwa, Marc Bigaud, Tobias Junt, Natasa Zamurovic, Philip Smith, Kathy D. McCoy, Pamela S. Ohashi, Frédéric Bornancin, Thomas Calzascia

J Immunol. 2019 Dec 1; 203(11): 2791–2806. Published online 2019 Oct 28. doi: 10.4049/jimmunol.1900327

PMCID:: PMC6859376

Abstract Article PDF–1.7M

Select item 677972110.

MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging

Annelies Demeyer, Elien Van Nuffel, Griet Baudelet, Yasmine Driege, Marja Kreike, David Muyllaert, Jens Staal, Rudi Beyaert

Front Immunol. 2019; 10: 2330. Published online 2019 Oct 1. doi: 10.3389/fimmu.2019.02330

PMCID:: PMC6779721

Abstract Article PDF–2.9M

Select item 670228711.

MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner

Annelies Demeyer, Ioannis Skordos, Yasmine Driege, Marja Kreike, Tino Hochepied, Mathijs Baens, Jens Staal, Rudi Beyaert

Front Immunol. 2019; 10: 1898. Published online 2019 Aug 14. doi: 10.3389/fimmu.2019.01898

PMCID:: PMC6702287

Abstract Article PDF–3.6M

Select item 665639112.

Targeting the CBM complex causes Treg cells to prime tumors for immune checkpoint therapy

Mauro Di Pilato, Edward Y. Kim, Bruno L. Cadilha, Jasper N. Pruessmann, Mazen N. Nasrallah, Davide Seruggia, Shariq M. Usmani, Sandra Misale, Valentina Zappulli, Esteban Carrizosa, Vinidhra Mani, Matteo Ligorio, Ross D. Warner, Benjamin D. Medoff, Francesco Marangoni, Alexandra-Chloe Villani, Thorsten R. Mempel

Nature. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Nature. 2019 Jun; 570(7759): 112–116. Published online 2019 May 15. doi: 10.1038/s41586-019-1215-2

PMCID:: PMC6656391

Abstract Article PDF–2.4M

Select item 661950113.

Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection

Benoit Briard, Rajendra Karki, R.K. Subbarao Malireddi, Anannya Bhattacharya, David E. Place, Jayadev Mavuluri, Jennifer L. Peters, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti

Nat Microbiol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Nat Microbiol. 2019 Feb; 4(2): 316–327. Published online 2018 Dec 3. doi: 10.1038/s41564-018-0298-0

PMCID:: PMC6619501

Abstract Article PDF–2.3M

Select item 653864614.

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Jürgen Ruland

Nat Commun. 2019; 10: 2352. Published online 2019 May 28. doi: 10.1038/s41467-019-10203-2

PMCID:: PMC6538646

Abstract Article PDF–2.0M

Select item 649447415.

CARD9⁺ Microglia Promote Antifungal Immunity via IL-1β and CXCL1-mediated Neutrophil Recruitment

Rebecca A. Drummond, Muthulekha Swamydas, Vasileios Oikonomou, Bing Zhai, Ivy M. Dambuza, Brian C. Schaefer, Andrea C. Bohrer, Katrin D. Mayer-Barber, Sergio A. Lira, Yoichiro Iwakura, Scott G. Filler, Gordon D. Brown, Bernhard Hube, Julian R. Naglik, Tobias M. Hohl, Michail S. Lionakis

Nat Immunol. Author manuscript; available in PMC 2019 Oct 17.

Published in final edited form as: Nat Immunol. 2019 May; 20(5): 559–570. Published online 2019 Apr 17. doi: 10.1038/s41590-019-0377-2

PMCID:: PMC6494474

Abstract Article PDF–2.4M

Select item 645065016.

T Cell Receptor Signals to NF-κB Are Transmitted by a Cytosolic p62-Bcl10-Malt1-IKK Signalosome

Suman Paul, Maria K. Traver, Anuj K. Kashyap, Michael A. Washington, Joseph R. Latoche, Brian C. Schaefer

Sci Signal. Author manuscript; available in PMC 2019 Apr 5.

Published in final edited form as: Sci Signal. 2014 May 13; 7(325): ra45. Published online 2014 May 13. doi: 10.1126/scisignal.2004882

PMCID:: PMC6450650

Abstract Article PDF–1.6M

Select item 637085017.

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

Jonathan J. Cho, Zhiwei Xu, Upasana Parthasarathy, Theodore T. Drashansky, Eric Y. Helm, Ashley N. Zuniga, Kyle J. Lorentsen, Samira Mansouri, Joshua Y. Cho, Mariola J. Edelmann, Duc M. Duong, Torben Gehring, Thomas Seeholzer, Daniel Krappmann, Mohammad N. Uddin, Danielle Califano, Rejean L. Wang, Lei Jin, Hongmin Li, Dongwen Lv, Daohong Zhou, Liang Zhou, Dorina Avram

Nat Commun. 2019; 10: 701. Published online 2019 Feb 11. doi: 10.1038/s41467-019-08605-3

PMCID:: PMC6370850

Abstract Article PDF–2.3M

Select item 622088818.

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

Mathijs Baens, Rocco Stirparo, Youlia Lampi, Delphine Verbeke, Roel Vandepoel, Jan Cools, Peter Marynen, Charles E. de Bock, Simon Bornschein

Eur J Immunol. 2018 Oct; 48(10): 1728–1738. Published online 2018 Aug 7. doi: 10.1002/eji.201847597

PMCID:: PMC6220888

Abstract Article PDF–1.5M

Select item 620771519.

Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes

Paulina Kasperkiewicz, Sonia Kołt, Tomasz Janiszewski, Katarzyna Groborz, Marcin Poręba, Scott J. Snipas, Guy S. Salvesen, Marcin Drąg

Sci Rep. 2018; 8: 15998. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34476-7

PMCID:: PMC6207715

Abstract Article PDF–3.7M

Select item 616846120.

Molecular architecture and regulation of BCL10-MALT1 filaments

Florian Schlauderer, Thomas Seeholzer, Ambroise Desfosses, Torben Gehring, Mike Strauss, Karl-Peter Hopfner, Irina Gutsche, Daniel Krappmann, Katja Lammens

Nat Commun. 2018; 9: 4041. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06573-8

PMCID:: PMC6168461

Abstract Article PDF–3.7M

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