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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 91226082.

SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination

Yongjuan Guan, Huijuan Lin, N Adrian Leu, Gordon Ruthel, Serge Y Fuchs, Luca Busino, Mengcheng Luo, P Jeremy Wang

Nucleic Acids Res. 2022 May 20; 50(9): 5129–5144. Published online 2022 Apr 30. doi: 10.1093/nar/gkac304

PMCID:: PMC9122608

Abstract Article PDF–13M

Select item 82822413.

Single‐cell RNA‐Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation

Yuanlin He, Qiuzhen Chen, Juncheng Dai, Yiqiang Cui, Chi Zhang, Xidong Wen, Jiazhao Li, Yue Xiao, Xiaoxu Peng, Mingxi Liu, Bin Shen, Jiahao Sha, Zhibin Hu, Jing Li, Wenjie Shu

Aging Cell. 2021 Jul; 20(7): e13424. Published online 2021 Jun 26. doi: 10.1111/acel.13424

PMCID:: PMC8282241

Abstract Article PDF–3.6M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 65441505.

Prdm9 and meiotic cohesin proteins cooperatively promote DNA double-strand break formation in mammalian spermatocytes

Tanmoy Bhattacharyya, Michael Walker, Natalie R Powers, Catherine Brunton, Alexander D Fine, Petko M Petkov, Mary Ann Handel

Curr Biol. Author manuscript; available in PMC 2020 Mar 18.

Published in final edited form as: Curr Biol. 2019 Mar 18; 29(6): 1002–1018.e7. Published online 2019 Mar 7. doi: 10.1016/j.cub.2019.02.007

Correction in:: Curr Biol. 2021 Mar 22; 31(6): 1351.

PMCID:: PMC6544150

Abstract Article PDF–2.6M

Select item 55032616.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 54419617.

Sororin is enriched at the central region of synapsed meiotic chromosomes

Philip W. Jordan, Craig Eyster, Jingrong Chen, Roberto J. Pezza, Susannah Rankin

Chromosome Res. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Chromosome Res. 2017 Jun; 25(2): 115–128. Published online 2017 Jan 3. doi: 10.1007/s10577-016-9542-8

PMCID:: PMC5441961

Abstract Article PDF–2.1M

Select item 52958218.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 50955919.

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

Laura Gómez-H, Natalia Felipe-Medina, Manuel Sánchez-Martín, Owen R. Davies, Isabel Ramos, Ignacio García-Tuñón, Dirk G. de Rooij, Ihsan Dereli, Attila Tóth, José Luis Barbero, Ricardo Benavente, Elena Llano, Alberto M. Pendas

Nat Commun. 2016; 7: 13298. Published online 2016 Oct 31. doi: 10.1038/ncomms13298

PMCID:: PMC5095591

Abstract Article PDF–4.9M

Select item 488966710.

Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L

Ayobami Ward, Jessica Hopkins, Matthew Mckay, Steve Murray, Philip W. Jordan

G3 (Bethesda) 2016 Jun; 6(6): 1713–1724. Published online 2016 Apr 16. doi: 10.1534/g3.116.029462

PMCID:: PMC4889667

Abstract Article PDF–2.5M

Select item 419802811.

Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion

Tristan Winters, Francois McNicoll, Rolf Jessberger

EMBO J. 2014 Jun 2; 33(11): 1256–1270. Published online 2014 May 5. doi: 10.1002/embj.201387330

PMCID:: PMC4198028

Abstract Article PDF–5.7M

Select item 419802712.

STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis

Tomoyuki Fukuda, Nanaho Fukuda, Ana Agostinho, Abrahan Hernández-Hernández, Anna Kouznetsova, Christer Höög

EMBO J. 2014 Jun 2; 33(11): 1243–1255. Published online 2014 May 5. doi: 10.1002/embj.201387329

PMCID:: PMC4198027

Abstract Article PDF–2.5M

Select item 408100713.

Meiosis-Specific Cohesin Component, Stag3 Is Essential for Maintaining Centromere Chromatid Cohesion, and Required for DNA Repair and Synapsis between Homologous Chromosomes

Jessica Hopkins, Grace Hwang, Justin Jacob, Nicklas Sapp, Rick Bedigian, Kazuhiro Oka, Paul Overbeek, Steve Murray, Philip W. Jordan

PLoS Genet. 2014 Jul; 10(7): e1004413. Published online 2014 Jul 3. doi: 10.1371/journal.pgen.1004413

PMCID:: PMC4081007

Abstract Article PDF–17M

Select item 406882414.

Mutant Cohesin in Premature Ovarian Failure

Sandrine Caburet, Valerie A. Arboleda, Elena Llano, Paul A. Overbeek, Jose Luis Barbero, Kazuhiro Oka, Wilbur Harrison, Daniel Vaiman, Ziva Ben-Neriah, Ignacio García-Tuñón, Marc Fellous, Alberto M. Pendás, Reiner A. Veitia, Eric Vilain

N Engl J Med. Author manuscript; available in PMC 2014 Sep 6.

Published in final edited form as: N Engl J Med. 2014 Mar 6; 370(10): 943–949. doi: 10.1056/NEJMoa1309635

PMCID:: PMC4068824

Abstract Article PDF–604K

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 338441817.

Meiotic cohesin complexes are essential for the formation of the axial element in mice

Elena Llano, Yurema Herrán, Ignacio García-Tuñón, Cristina Gutiérrez-Caballero, Enrique de Álava, José Luis Barbero, John Schimenti, Dirk G. de Rooij, Manuel Sánchez-Martín, Alberto M. Pendás

J Cell Biol. 2012 Jun 25; 197(7): 877–885. doi: 10.1083/jcb.201201100

PMCID:: PMC3384418

Abstract Article PDF–2.4M

Select item 327655418.

Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis

Tomoyuki Fukuda, Florencia Pratto, John C. Schimenti, James M. A. Turner, R. Daniel Camerini-Otero, Christer Höög

PLoS Genet. 2012 Feb; 8(2): e1002485. Published online 2012 Feb 9. doi: 10.1371/journal.pgen.1002485

PMCID:: PMC3276554

Abstract Article PDF–1.0M

Select item 322952419.

Meiosis in Mice without a Synaptonemal Complex

Anna Kouznetsova, Ricardo Benavente, Albert Pastink, Christer Höög

PLoS One. 2011; 6(12): e28255. Published online 2011 Dec 2. doi: 10.1371/journal.pone.0028255

PMCID:: PMC3229524

Abstract Article PDF–3.4M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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