PMC Links for GEO Profiles (Select 126721348) - PMC

Links from GEO Profiles

Items: 1 to 20 of 32

<< First< Prev

Page of 2

Select item 101929281.

The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination

Zubin Zhang, Mei Li, Peng Lin, Ying Ren, Yuanming He, Siyu Wang, Yujia Xu, Biyin Cao, Guanghui Wang, Michael F. Moran, Xinliang Mao

J Biol Chem. 2023 May; 299(5): 104675. Published online 2023 Apr 5. doi: 10.1016/j.jbc.2023.104675

PMCID:: PMC10192928

Abstract Article PDF–3.6M

Select item 88451262.

Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males

Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David A. Jacobson, Roland Stein

Cell Rep. Author manuscript; available in PMC 2022 Feb 15.

Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109813. doi: 10.1016/j.celrep.2021.109813

PMCID:: PMC8845126

Abstract Article PDF–2.8M

Select item 86016323.

Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity

Floris Leenders, Nathalie Groen, Natascha de Graaf, Marten A. Engelse, Ton J. Rabelink, Eelco J. P. de Koning, Françoise Carlotti

Front Immunol. 2021; 12: 690379. Published online 2021 Nov 4. doi: 10.3389/fimmu.2021.690379

PMCID:: PMC8601632

Abstract Article PDF–14M

Select item 80090484.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 70291235.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao

J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724

PMCID:: PMC7029123

Abstract Article PDF–3.6M

Select item 61666826.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 59186327.

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

Elvira Ganic, Tania Singh, Cheng Luan, João Fadista, Jenny K. Johansson, Holly Ann Cyphert, Hedvig Bennet, Petter Storm, Gaëlle Prost, Henrik Ahlenius, Erik Renström, Roland Stein, Leif Groop, Malin Fex, Isabella Artner

Cell Rep. Author manuscript; available in PMC 2018 Apr 26.

Published in final edited form as: Cell Rep. 2016 Mar 1; 14(8): 1991–2002. Published online 2016 Feb 18. doi: 10.1016/j.celrep.2016.02.002

PMCID:: PMC5918632

Abstract Article PDF–2.5M

Select item 57983338.

MAFA missense mutation causes familial insulinomatosis and diabetes mellitus

Donato Iacovazzo, Sarah E. Flanagan, Emily Walker, Rosana Quezado, Fernando Antonio de Sousa Barros, Richard Caswell, Matthew B. Johnson, Matthew Wakeling, Michael Brändle, Min Guo, Mary N. Dang, Plamena Gabrovska, Bruno Niederle, Emanuel Christ, Stefan Jenni, Bence Sipos, Maike Nieser, Andrea Frilling, Ketan Dhatariya, Philippe Chanson, Wouter W. de Herder, Björn Konukiewitz, Günter Klöppel, Roland Stein, Márta Korbonits, Sian Ellard

Proc Natl Acad Sci U S A. 2018 Jan 30; 115(5): 1027–1032. Published online 2018 Jan 16. doi: 10.1073/pnas.1712262115

PMCID:: PMC5798333

Abstract Article PDF–1.1M

Select item 57038789.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Abstract Article PDF–3.7M

Select item 566746710.

PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration

Yaxi Zhu, Qian Liu, Zhiguang Zhou, Yasuhiro Ikeda

Stem Cell Res Ther. 2017; 8: 240. Published online 2017 Nov 2. doi: 10.1186/s13287-017-0694-z

PMCID:: PMC5667467

Abstract Article PDF–565K

Select item 565658111.

miR-204 is associated with an endocrine phenotype in human pancreatic islets but does not regulate the insulin mRNA through MAFA

Ilaria Marzinotto, Silvia Pellegrini, Cristina Brigatti, Rita Nano, Raffaella Melzi, Alessia Mercalli, Daniela Liberati, Valeria Sordi, Maurizio Ferrari, Massimo Falconi, Claudio Doglioni, Philippe Ravassard, Lorenzo Piemonti, Vito Lampasona

Sci Rep. 2017; 7: 14051. Published online 2017 Oct 25. doi: 10.1038/s41598-017-13622-7

PMCID:: PMC5656581

Abstract Article PDF–1.8M

Select item 563699112.

Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis

Siyu Wang, Jiaxiang Juan, Zubin Zhang, Yanyun Du, Yujia Xu, Jiefei Tong, Biyin Cao, Michael F Moran, Yuanying Zeng, Xinliang Mao

Cell Death Dis. 2017 Sep; 8(9): e3058. Published online 2017 Sep 21. doi: 10.1038/cddis.2017.450

PMCID:: PMC5636991

Abstract Article PDF–3.7M

Select item 461397913.

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function

David W. Scoville, Holly A. Cyphert, Lan Liao, Jianming Xu, Al Reynolds, Shuangli Guo, Roland Stein

Diabetes. 2015 Nov; 64(11): 3772–3783. Published online 2015 Jul 15. doi: 10.2337/db15-0281

PMCID:: PMC4613979

Abstract Article PDF–1.5M

Select item 392238314.

MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin⁺ cells

Shih-Hwa Chiou, Shih-Jen Chen, Yuh-Lih Chang, Yu-Chih Chen, Hsin-Yang Li, Dow-Tien Chen, Hsin-Hui Wang, Chia-Ming Chang, Yi-Jen Chen, Hung-Hai Ku

J Cell Mol Med. 2011 Mar; 15(3): 612–624. Published online 2010 Feb 16. doi: 10.1111/j.1582-4934.2010.01034.x

PMCID:: PMC3922383

Abstract Article PDF–1.3M

Select item 384106315.

Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma

Z Hamze, C Vercherat, A Bernigaud-Lacheretz, Wissam Bazzi, R Bonnavion, J Lu, A Calender, C Pouponnot, P Bertolino, C Roche, R Stein, JY Scoazec, C X Zhang, M Cordier-Bussat

Endocr Relat Cancer. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Endocr Relat Cancer. 2013 Dec; 20(6): 833–848. Published online 2013 Oct 24. doi: 10.1530/ERC-13-0164

PMCID:: PMC3841063

Abstract Article PDF–1.5M

Select item 375496816.

Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes

Rémy Bonnavion, Rami Jaafar, Julie Kerr-Conte, Fouzia Assade, Esther van Stralen, Emmanuelle Leteurtre, Célio Pouponnot, Sofia Gargani, François Pattou, Philippe Bertolino, Martine Cordier-Bussat, Jieli Lu, Chang Xian Zhang

PLoS One. 2013; 8(8): e72194. Published online 2013 Aug 27. doi: 10.1371/journal.pone.0072194