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Items: 1 to 20 of 39

1.
Oxidation Driven Reversal of PIP2-dependent Gating in GIRK2 Channels
Sun-Joo Lee, Shoji Maeda, Jian Gao, Colin G Nichols
Function (Oxf) 2023; 4(3): zqad016. Published online 2023 Apr 10. doi: 10.1093/function/zqad016
PMCID:
PMC10165546
AbstractArticlePDF–5.8M
2.
Association of KCNJ6 rs2070995 and methadone response for pain management in advanced cancer at end-of-life
Deniz Ozberk, Alison Haywood, Heidi G. Sutherland, Chieh Yu, Cassie L. Albury, Mathew Zunk, Rani George, Phillip Good, Lyn R. Griffiths, Janet Hardy, Larisa M. Haupt
Sci Rep. 2022; 12: 17422. Published online 2022 Oct 19. doi: 10.1038/s41598-022-21180-w
PMCID:
PMC9582209
AbstractArticlePDF–966K
3.
Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons
Dina Popova, Isabel Gameiro-Ros, Mark M. Youssef, Petronio Zalamea, Ayeshia D. Morris, Iya Prytkova, Azadeh Jadali, Kelvin Y. Kwan, Chella Kamarajan, Jessica E. Salvatore, Xiaoling Xuei, David B. Chorlian, Bernice Porjesz, Samuel Kuperman, Danielle M. Dick, Alison Goate, Howard J. Edenberg, Jay A. Tischfield, Zhiping P. Pang, Paul A. Slesinger, Ronald P. Hart
Mol Psychiatry. 2023; 28(2): 746–758. Published online 2022 Oct 7. doi: 10.1038/s41380-022-01818-x
PMCID:
PMC9542475
AbstractArticlePDF–5.0M
4.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
Heteromultimerization of G-Protein-Gated Inwardly Rectifying K+ Channel Proteins GIRK1 and GIRK2 and Their Altered Expression in weaver Brain
Y. Joyce Liao, Yuh Nung Jan, Lily Yeh Jan
J Neurosci. 1996 Nov 15; 16(22): 7137–7150. doi: 10.1523/JNEUROSCI.16-22-07137.1996
PMCID:
PMC6578936
AbstractArticlePDF–2.0M
8.
Structure‐Activity Relationship of NF023 Derivatives Binding to XIAP‐BIR1
Dr. Luca Sorrentino, Dr. Federica Cossu, Dr. Mario Milani, Bilge Malkoc, Dr. Wen‐Chieh Huang, Dr. Shwu‐Chen Tsay, Prof. Jih Ru Hwu, Dr. Eloise Mastrangelo
ChemistryOpen. 2019 Apr; 8(4): 476–482. Published online 2019 Apr 12. doi: 10.1002/open.201900059
PMCID:
PMC6460348
AbstractArticlePDF–1.1M
9.
Gi/o-coupled muscarinic receptors co-localize with GIRK channel for efficient channel activation
Michihiro Tateyama, Yoshihiro Kubo
PLoS One. 2018; 13(9): e0204447. Published online 2018 Sep 21. doi: 10.1371/journal.pone.0204447
PMCID:
PMC6150519
AbstractArticlePDF–9.5M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Genetic correlates of the development of Theta Event Related Oscillations in Adolescents and Young Adults
David B. Chorlian, Madhavi Rangaswamy, Niklas Manz, Jacquelyn L. Meyers, Sun J. Kang, Chella Kamarajan, Ashwini K. Pandey, Jen-Chyong Wang, Leah Wetherill, Howard Edenberg, Bernice Porjesz
Int J Psychophysiol. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Int J Psychophysiol. 2017 May; 115: 24–39. Published online 2016 Nov 12. doi: 10.1016/j.ijpsycho.2016.11.007
PMCID:
PMC5456461
AbstractArticlePDF–2.1M
12.
A KCNJ6 gene polymorphism modulates theta oscillations during reward processing
Chella Kamarajan, Ashwini K. Pandey, David B. Chorlian, Niklas Manz, Arthur T. Stimus, Howard J. Edenberg, Leah Wetherill, Marc Schuckit, Jen-Chyong Wang, Samuel Kuperman, John Kramer, Jay A. Tischfield, Bernice Porjesz
Int J Psychophysiol. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Int J Psychophysiol. 2017 May; 115: 13–23. Published online 2016 Dec 16. doi: 10.1016/j.ijpsycho.2016.12.007
PMCID:
PMC5392377
AbstractArticlePDF–2.7M
13.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
14.
X-ray structure of the mammalian GIRK2 – ß? G protein complex
Matthew R. Whorton, Roderick MacKinnon
Nature. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Nature. 2013 Jun 13; 498(7453): 190–197. Published online 2013 Jun 5. doi: 10.1038/nature12241
PMCID:
PMC4654628
AbstractArticlePDF–2.1M
15.
Keppen-Lubinsky Syndrome Is Caused by Mutations in the Inwardly Rectifying K+ Channel Encoded by KCNJ6
Andrea Masotti, Paolo Uva, Laura Davis-Keppen, Lina Basel-Vanagaite, Lior Cohen, Elisa Pisaneschi, Antonella Celluzzi, Paola Bencivenga, Mingyan Fang, Mingyu Tian, Xun Xu, Marco Cappa, Bruno Dallapiccola
Am J Hum Genet. 2015 Feb 5; 96(2): 295–300. doi: 10.1016/j.ajhg.2014.12.011
PMCID:
PMC4320262
AbstractArticlePDF–933K
16.
Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome
Tyler K. Best, Nathan P. Cramer, Lina Chakrabarti, Tarik F. Haydar, Zygmunt Galdzicki
Exp Neurol. Author manuscript; available in PMC 2014 Aug 6.
Published in final edited form as: Exp Neurol. 2012 Feb; 233(2): 749–757. Published online 2011 Dec 8. doi: 10.1016/j.expneurol.2011.11.033
PMCID:
PMC4123861
AbstractArticlePDF–653K
17.
VARIATIONS IN POTASSIUM CHANNEL GENES ARE ASSOCIATED WITH BREAST PAIN IN WOMEN PRIOR TO BREAST CANCER SURGERY
Dale J. Langford, Claudia West, Charles Elboim, Bruce A. Cooper, Gary Abrams, Steven M. Paul, Brian L. Schmidt, Jon D. Levine, John D. Merriman, Anand Dhruva, John Neuhaus, Heather Leutwyler, Christina Baggott, Carmen Ward Sullivan, Bradley E. Aouizerat, Christine Miaskowski
J Neurogenet. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: J Neurogenet. 2014 Mar-Jun; 28(0): 122–135. Published online 2014 Jan 7. doi: 10.3109/01677063.2013.856430
PMCID:
PMC4035357
AbstractArticlePDF–453K
18.
Associations Between KCNJ6 (GIRK2) Gene Polymorphisms and Pain-Related Phenotypes
Stephen Bruehl, Jerod S. Denton, Daniel Lonergan, Mary Ellen Koran, Melissa Chont, Christopher Sobey, Shanik Fernando, William S. Bush, Puneet Mishra, Tricia A. Thornton-Wells
Pain. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Pain. 2013 Dec; 154(12): 10.1016/j.pain.2013.08.026. Published online 2013 Aug 28. doi: 10.1016/j.pain.2013.08.026
PMCID:
PMC3845348
AbstractArticlePDF–131K
19.
Molecular mechanism underlying ethanol activation of G-protein–gated inwardly rectifying potassium channels
Karthik Bodhinathan, Paul A. Slesinger
Proc Natl Acad Sci U S A. 2013 Nov 5; 110(45): 18309–18314. Published online 2013 Oct 21. doi: 10.1073/pnas.1311406110
PMCID:
PMC3831446
AbstractArticlePDF–1.1M
20.
Rare independent mutations in renal salt handling genes contribute to blood pressure variation
Weizhen Ji, Jia Nee Foo, Brian J. O'Roak, Hongyu Zhao, Martin G. Larson, David B. Simon, Christopher Newton-Cheh, Matthew W. State, Daniel Levy, Richard P. Lifton
Nat Genet. Author manuscript; available in PMC 2013 Sep 8.
Published in final edited form as: Nat Genet. 2008 May; 40(5): 592–599. Published online 2008 Apr 6. doi: 10.1038/ng.118
PMCID:
PMC3766631
AbstractArticlePDF–1.5M

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