PMC Links for GEO Profiles (Select 126813178) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108827184.

The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice

Andrea Benzi, Markus Heine, Sonia Spinelli, Annalisa Salis, Anna Worthmann, Björn Diercks, Cecilia Astigiano, Raúl Pérez Mato, Adela Memushaj, Laura Sturla, Valerio Vellone, Gianluca Damonte, Michelle Y. Jaeckstein, Friedrich Koch-Nolte, Hans-Willi Mittrücker, Andreas H. Guse, Antonio De Flora, Joerg Heeren, Santina Bruzzone

Front Endocrinol (Lausanne) 2023; 14: 1251351. Published online 2024 Feb 6. doi: 10.3389/fendo.2023.1251351

PMCID:: PMC10882718

Abstract Article PDF–5.2M

Select item 104652135.

TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy

Binfeng Yu, Lini Jin, Xi Yao, Yi Zhang, Gensheng Zhang, Fangqin Wang, Xinwan Su, Qiuyuan Fang, Liang Xiao, Yi Yang, Lin-Hua Jiang, Jianghua Chen, Wei Yang, Weiqiang Lin, Fei Han

Theranostics. 2023; 13(13): 4356–4375. Published online 2023 Jul 31. doi: 10.7150/thno.84655

PMCID:: PMC10465213

Abstract Article PDF–13M

Select item 98262876.

Protein kinase C‐mediated phosphorylation of transient receptor potential melastatin type 2 Thr738 counteracts the effect of cytosolic Ca²⁺ and elevates the temperature threshold

Makiko Kashio, Satoru Masubuchi, Makoto Tominaga

J Physiol. 2022 Oct 1; 600(19): 4287–4302. Published online 2022 Sep 12. doi: 10.1113/JP283350

PMCID:: PMC9826287

Abstract Article PDF–12M

Select item 92330787.

Functional Coupling of TRPM2 and Extrasynaptic NMDARs Exacerbates Excitotoxicity in Ischemic Brain Injury

Pengyu Zong, Jianlin Feng, Zhichao Yue, Yunfeng Li, Gongxiong Wu, Baonan Sun, Yanlin He, Barbara Miller, Albert S. Yu, Zhongping Su, Jia Xie, Yasuo Mori, Bing Hao, Lixia Yue

Neuron. Author manuscript; available in PMC 2023 Jun 15.

Published in final edited form as: Neuron. 2022 Jun 15; 110(12): 1944–1958.e8. Published online 2022 Apr 13. doi: 10.1016/j.neuron.2022.03.021

PMCID:: PMC9233078

Abstract Article PDF–3.4M

Select item 91039478.

TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis

Yunting Zhang, Fan Ying, Xiaoyu Tian, Zhenchuan Lei, Xiao Li, Chun-Yin Lo, Jingxuan Li, Liwen Jiang, Xiaoqiang Yao

Cells. 2022 May; 11(9): 1423. Published online 2022 Apr 22. doi: 10.3390/cells11091423

PMCID:: PMC9103947

Abstract Article PDF–5.9M

Select item 87959119.

TRPM2 Is Not Required for T-Cell Activation and Differentiation

Niels C. Lory, Mikolaj Nawrocki, Martina Corazza, Joanna Schmid, Valéa Schumacher, Tanja Bedke, Stephan Menzel, Friedrich Koch-Nolte, Andreas H. Guse, Samuel Huber, Hans-Willi Mittrücker

Front Immunol. 2021; 12: 778916. Published online 2022 Jan 14. doi: 10.3389/fimmu.2021.778916

PMCID:: PMC8795911

Abstract Article PDF–3.8M

Select item 866060110.

Knockdown of transient receptor potential melastatin 2 reduces renal fibrosis and inflammation by blocking transforming growth factor-β1-activated JNK1 activation in diabetic mice

Feng Hu, Yun Yu, Feng Lu, Xiaoshu Cheng

Aging (Albany NY) 2021 Nov 30; 13(22): 24605–24620. Published online 2021 Nov 29. doi: 10.18632/aging.203694

PMCID:: PMC8660601

Abstract Article PDF–1.7M

Select item 851491711.

Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels

Robert M. Dietz, James E. Orfila, Nicholas Chalmers, Crystal Minjarez, Jose Vigil, Guying Deng, Nidia Quillinan, Paco S. Herson

Neural Plast. 2021; 2021: 8774663. Published online 2021 Oct 6. doi: 10.1155/2021/8774663

PMCID:: PMC8514917

Abstract Article PDF–1.5M

Select item 833712412.

Deficiency of ROS-Activated TRPM2 Channel Protects Neurons from Cerebral Ischemia-Reperfusion Injury through Upregulating Autophagy

Xupang Hu, Lijuan Wu, Xingyu Liu, Yi Zhang, Min Xu, Qiuyuan Fang, Lin Lu, Jianguo Niu, Tarek Mohamed Abd El-Aziz, Lin-Hua Jiang, Fangfang Li, Wei Yang

Oxid Med Cell Longev. 2021; 2021: 7356266. Published online 2021 Jul 27. doi: 10.1155/2021/7356266

PMCID:: PMC8337124

Abstract Article PDF–2.1M

Select item 823328313.

Mapping the expression of transient receptor potential channels across murine placental development

Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens

Cell Mol Life Sci. 2021 Jun; 78(11): 4993–5014. Published online 2021 Apr 21. doi: 10.1007/s00018-021-03837-3

PMCID:: PMC8233283

Abstract Article PDF–4.1M

Select item 808523414.

TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide

Hassan Morad, Suaib Luqman, Chun-Hsiang Tan, Victoria Swann, Peter A. McNaughton

Sci Rep. 2021; 11: 9339. Published online 2021 Apr 29. doi: 10.1038/s41598-021-88224-5

PMCID:: PMC8085234

Abstract Article PDF–3.8M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 769323716.

TRPM2 promotes autophagic degradation in vascular smooth muscle cells

Qiannan Zhao, Jingxuan Li, Wing-Hung Ko, Yiu-Wa Kwan, Liwen Jiang, Lei Sun, Xiaoqiang Yao

Sci Rep. 2020; 10: 20719. Published online 2020 Nov 26. doi: 10.1038/s41598-020-77620-y

PMCID:: PMC7693237

Abstract Article PDF–4.4M

Select item 761379517.

Heat detection by the TRPM2 ion channel

Bruno Vilar, Chun-Hsiang Tan, Peter A. McNaughton

Nature. Author manuscript; available in PMC 2022 Nov 7.

Published in final edited form as: Nature. 2020 Aug 1; 584(7820): E5–E12. Published online 2020 Aug 12. doi: 10.1038/s41586-020-2510-7

PMCID:: PMC7613795

Article PDF–1.2M

Select item 761317718.

A synaptic temperature sensor for body cooling

Gretel B. Kamm, Juan C. Boffi, Kristina Zuza, Sara Nencini, Joaquin Campos, Katrin Schrenk-Siemens, Ivo Sonntag, Burce Kabaoğlu, Muad Y. Abd El Hay, Yvonne Schwarz, Anke Tappe-Theodor, Dieter Bruns, Claudio Acuna, Thomas Kuner, Jan Siemens

Neuron. Author manuscript; available in PMC 2022 Jul 28.

Published in final edited form as: Neuron. 2021 Oct 20; 109(20): 3283–3297.e11. doi: 10.1016/j.neuron.2021.10.001

PMCID:: PMC7613177

Abstract Article PDF–3.2M

Select item 761227619.

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

Kun Song, Hong Wang, Gretel B. Kamm, Jörg Pohle, Fernanda de Castro Reis, Paul Heppenstall, Hagen Wende, Jan Siemens

Science. Author manuscript; available in PMC 2022 Jan 27.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): 1393–1398. Published online 2016 Aug 25. doi: 10.1126/science.aaf7537

PMCID:: PMC7612276

Abstract Article PDF–1.9M

Select item 727212020.

The Sensory Coding of Warm Perception

Ricardo Paricio-Montesinos, Frederick Schwaller, Annapoorani Udhayachandran, Florian Rau, Jan Walcher, Roberta Evangelista, Joris Vriens, Thomas Voets, James F.A. Poulet, Gary R. Lewin

Neuron. 2020 Jun 3; 106(5): 830–841.e3. doi: 10.1016/j.neuron.2020.02.035

PMCID:: PMC7272120

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