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Select item 111050601.

GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity

Rocío Vila-Bedmar, Marta Cruces-Sande, Alba C. Arcones, Hanneke L. D. M. Willemen, Patricia Prieto, Isabel Moreno-Indias, Daniel Díaz-Rodríguez, Sara Francisco, Rafael I. Jaén, Carolina Gutiérrez-Repiso, Cobi J. Heijnen, Lisardo Boscá, Manuel Fresno, Annemieke Kavelaars, Federico Mayor, Jr, Cristina Murga

Cell Mol Life Sci. 2020 Dec; 77(23): 4957–4976. Published online 2020 Jan 11. doi: 10.1007/s00018-019-03442-5

PMCID:: PMC11105060

Abstract Article PDF–5.1M

Select item 109972892.

GRK2–YAP signaling is implicated in pulmonary arterial hypertension development

Peng Ye, Yunfei Deng, Yue Gu, Pengfei Liu, Jie Luo, Jiangqin Pu, Jingyu Chen, Yu Huang, Nanping Wang, Yong Ji, Shaoliang Chen

Chin Med J (Engl) 2024 Apr 5; 137(7): 846–858. Published online 2024 Jan 19. doi: 10.1097/CM9.0000000000002946

PMCID:: PMC10997289

Abstract Article PDF–13M

Select item 108091223.

Hepatic GRK2 is dispensable for glucose homeostasis and other key metabolic parameters in mice

Antwi-Boasiako Oteng, Srinivas Pittala, Andrea Kliewer, Yishu Qiu, Jürgen Wess

Mol Metab. 2024 Jan; 79: 101866. Published online 2023 Dec 28. doi: 10.1016/j.molmet.2023.101866

PMCID:: PMC10809122

Abstract Article PDF–2.3M

Select item 102830274.

Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons

Cecilia Perdices-Lopez, María S. Avendaño, Alexia Barroso, Francisco Gaytán, Francisco Ruiz-Pino, Maria J. Vázquez, Silvia Leon, Yong Bhum Song, Veronica Sobrino, Violeta Heras, Antonio Romero-Ruiz, Juan Roa, Federico Mayor, Jr, Cristina Murga, Leonor Pinilla, Ursula B. Kaiser, Manuel Tena-Sempere

Metabolism. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Metabolism. 2022 Apr; 129: 155141. Published online 2022 Jan 22. doi: 10.1016/j.metabol.2022.155141

PMCID:: PMC10283027

Abstract Article PDF–1.1M

Select item 101820965.

Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1

Hiroki Yano, Kenji Onoue, Shiho Tokinaga, Tomoko Ioka, Satomi Ishihara, Yukihiro Hashimoto, Yasuki Nakada, Hitoshi Nakagawa, Tomoya Ueda, Ayako Seno, Taku Nishida, Makoto Watanabe, Yoshihiko Saito

Sci Rep. 2023; 13: 7707. Published online 2023 May 12. doi: 10.1038/s41598-023-34209-5

PMCID:: PMC10182096

Abstract Article PDF–2.4M

Select item 100905436.

GRK2 differentially regulates FcεRI and MRGPRB2-mediated responses in mast cells

Monica Thapaliya, Hydar Ali

Front Immunol. 2023; 14: 1155777. Published online 2023 Mar 29. doi: 10.3389/fimmu.2023.1155777

PMCID:: PMC10090543

Abstract Article PDF–4.7M

Select item 97030787.

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions

Katharina M. Glaser, Teresa K. Tarrant, Tim Lämmermann

Front Immunol. 2022; 13: 1039803. Published online 2022 Nov 14. doi: 10.3389/fimmu.2022.1039803

PMCID:: PMC9703078

Abstract Article PDF–20M

Select item 96721228.

Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis

Guoxin Xu, Yanping Gong, Fenying Lu, Bin Wang, Zaixing Yang, Long Chen, Jingyu Min, Cuie Cheng, Tingwang Jiang

Sci Rep. 2022; 12: 19772. Published online 2022 Nov 17. doi: 10.1038/s41598-022-21816-x

PMCID:: PMC9672122

Abstract Article PDF–11M

Select item 89261569.

Neutrophils self-limit swarming to contain bacterial growth in vivo

Korbinian Kienle, Katharina M. Glaser, Sarah Eickhoff, Michael Mihlan, Konrad Knöpper, Eduardo Reátegui, Maximilian W. Epple, Matthias Gunzer, Ralf Baumeister, Teresa K. Tarrant, Ronald N. Germain, Daniel Irimia, Wolfgang Kastenmüller, Tim Lämmermann

Science. Author manuscript; available in PMC 2022 Jun 18.

Published in final edited form as: Science. 2021 Jun 18; 372(6548): eabe7729. doi: 10.1126/science.abe7729

PMCID:: PMC8926156

Abstract Article PDF–3.1M

Select item 891144210.

Myocardial GRK2 Reduces Fatty Acid Metabolism and β-Adrenergic Receptor-Mediated Mitochondrial Responses

Ruxu Zhai, Erika L. Varner, Ajay Rao, Sunil Karhadkar, Antonio Di Carlo, Nathaniel W. Snyder, Priscila Y. Sato

Int J Mol Sci. 2022 Mar; 23(5): 2777. Published online 2022 Mar 3. doi: 10.3390/ijms23052777

PMCID:: PMC8911442

Abstract Article PDF–1.9M

Select item 890862011.

GRK2 regulates group 2 innate lymphoid cell mobilization in sepsis

Dengming Lai, Weiwei Chen, Kai Zhang, Melanie J. Scott, Yuehua Li, Timothy R. Billiar, Mark A. Wilson, Jie Fan

Mol Med. 2022; 28: 32. Published online 2022 Mar 10. doi: 10.1186/s10020-022-00459-8

PMCID:: PMC8908620

Abstract Article PDF–3.1M

Select item 881218312.

Neuronal GRK2 regulates microglial activation and contributes to electroacupuncture analgesia on inflammatory pain in mice

Yu Chen, Yang Zhou, Xiao-Chen Li, Xue Ma, Wen-Li Mi, Yu-Xia Chu, Yan-Qing Wang, Qi-Liang Mao-Ying

Biol Res. 2022; 55: 5. Published online 2022 Feb 3. doi: 10.1186/s40659-022-00374-6

PMCID:: PMC8812183

Abstract Article PDF–2.6M

Select item 864881713.

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells

Yanghui Sheng, Lujing Chen, Xiaozhi Ren, Zheng Jiang, King-Wai Yau

Sci Rep. 2021; 11: 23424. Published online 2021 Dec 6. doi: 10.1038/s41598-021-02832-9

PMCID:: PMC8648817

Abstract Article PDF–2.7M

Select item 846468114.

Nintedanib Regulates GRK2 and CXCR2 to Reduce Neutrophil Recruitment in Endotoxin-Induced Lung Injury

Vincent Yi-Fong Su, Wei-Chih Chen, Wen-Kuang Yu, Huai-Hsuan Wu, Hao Chen, Kuang-Yao Yang

Int J Mol Sci. 2021 Sep; 22(18): 9898. Published online 2021 Sep 13. doi: 10.3390/ijms22189898

PMCID:: PMC8464681

Abstract Article PDF–4.0M

Select item 815994415.

GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells

Jonathan Snyder, Atreju I Lackey, G. Schuyler Brown, Melisa Diaz, Tian Yuzhen, Priscila Y. Sato

Sci Rep. 2021; 11: 11129. Published online 2021 May 27. doi: 10.1038/s41598-021-90253-z

PMCID:: PMC8159944

Abstract Article PDF–2.3M

Select item 800294116.

Cardiac GRK2 Protein Levels Show Sexual Dimorphism during Aging and Are Regulated by Ovarian Hormones

Alba C. Arcones, Melanie Raquel Martínez-Cignoni, Rocío Vila-Bedmar, Claudia Yáñez, Isabel Lladó, Ana M. Proenza, Federico Mayor, Jr., Cristina Murga

Cells. 2021 Mar; 10(3): 673. Published online 2021 Mar 17. doi: 10.3390/cells10030673

PMCID:: PMC8002941

Abstract Article PDF–1.9M

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 793160118.

GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo

Alba C. Arcones, Rocío Vila-Bedmar, Mercedes Mirasierra, Marta Cruces-Sande, Mario Vallejo, Ben Jones, Alejandra Tomas, Federico Mayor, Jr, Cristina Murga

BMC Biol. 2021; 19: 40. Published online 2021 Mar 3. doi: 10.1186/s12915-021-00966-w

PMCID:: PMC7931601

Abstract Article PDF–1.8M

Select item 778099519.

Opsin 3–G_αs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2

Amy D. Wu, William Dan, Yi Zhang, Shruti Vemaraju, Brian A. Upton, Richard A. Lang, Ethan D. Buhr, Dan E. Berkowitz, George Gallos, Charles W. Emala, Peter D. Yim

Am J Respir Cell Mol Biol. 2021 Jan; 64(1): 59–68. doi: 10.1165/rcmb.2020-0392OC

PMCID:: PMC7780995

Abstract Article PDF–1.2M

Select item 741599120.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

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