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Select item 116295741.

YAP1 preserves tubular mitochondrial quality control to mitigate diabetic kidney disease

Siyang Ye, Meng Zhang, Xunhua Zheng, Suchun Li, Yuting Fan, Yiqin Wang, Huajing Peng, Sixiu Chen, Jiayi Yang, Li Tan, Manhuai Zhang, Peichen Xie, Xiaoyan Li, Ning Luo, Zhipeng Wang, Leigang Jin, Xiaoping Wu, Yong Pan, Jinjin Fan, Yi Zhou, Sydney C.W. Tang, Bin Li, Wei Chen

Redox Biol. 2024 Dec; 78: 103435. Published online 2024 Nov 23. doi: 10.1016/j.redox.2024.103435

PMCID:: PMC11629574

Abstract Article PDF–22M

Select item 114844802.

SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation

Ana Paula Dias, Taha Rehmani, Billi Dawn Applin, Maysoon Salih, Balwant Tuana

Open Biol. 2024 Oct; 14(10): rsob240206. Published online October 17, 2024. doi: 10.1098/rsob.240206

PMCID:: PMC11484480

Abstract Article PDF–3.5M

Select item 114726483.

Yap1 alleviates sepsis associated encephalopathy by inhibiting hippocampus ferroptosis via maintaining mitochondrial dynamic homeostasis

Xin Yang, Haifeng Duan, Sirui Li, Jing Zhang, Liang Dong, Jingli Ding, Xinyi Li

J Cell Mol Med. 2024 Oct; 28(19): e70156. Published online 2024 Oct 14. doi: 10.1111/jcmm.70156

PMCID:: PMC11472648

Abstract Article PDF–4.7M

Select item 114610714.

Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis

Ana Paula Dias, Taha Rehmani, Maysoon Salih, Balwant Tuana

Open Biol. 2024 Oct; 14(10): 240094. Published online October 9, 2024. doi: 10.1098/rsob.240094

PMCID:: PMC11461071

Abstract Article PDF–2.1M

Select item 114526525.

SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP

Taha Rehmani, Ana Paula Dias, Billi Dawn Applin, Maysoon Salih, Balwant S Tuana

Life Sci Alliance. 2024 Dec; 7(12): e202302545. Published online 2024 Oct 4. doi: 10.26508/lsa.202302545

PMCID:: PMC11452652

Abstract Article PDF–3.7M

Select item 113721146.

The Foxo1-YAP-Notch1 axis reprograms STING-mediated innate immunity in NASH progression

Dongwei Xu, Xiaoye Qu, Tao Yang, Mingwei Sheng, Xiyun Bian, Yongqiang Zhan, Yizhu Tian, Yuanbang Lin, Yuting Jin, Xiao Wang, Michael Ke, Longfeng Jiang, Changyong Li, Qiang Xia, Douglas G. Farmer, Bibo Ke

Exp Mol Med. 2024 Aug; 56(8): 1843–1855. Published online 2024 Aug 9. doi: 10.1038/s12276-024-01280-5

PMCID:: PMC11372114

Abstract Article PDF–4.0M

Select item 113698907.

The YAP–TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress

Carlos Anerillas, Krystyna Mazan-Mamczarz, Allison B. Herman, Rachel Munk, Kwan-Wood Gabriel Lam, Miguel Calvo-Rubio, Amanda Garrido, Dimitrios Tsitsipatis, Jennifer L. Martindale, Gisela Altés, Martina Rossi, Yulan Piao, Jinshui Fan, Chang-Yi Cui, Supriyo De, Kotb Abdelmohsen, Rafael de Cabo, Myriam Gorospe

Nat Aging. Author manuscript; available in PMC 2024 Sep 3.

Published in final edited form as: Nat Aging. 2023 Oct; 3(10): 1237–1250. Published online 2023 Sep 4. doi: 10.1038/s43587-023-00480-4

PMCID:: PMC11369890

Abstract Article PDF–5.6M

Select item 113104448.

Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms

Soeun Kang, Maciek R. Antoniewicz, Nissim Hay

Nat Commun. 2024; 15: 6777. Published online 2024 Aug 8. doi: 10.1038/s41467-024-51117-y

PMCID:: PMC11310444

Abstract Article PDF–4.5M

Select item 112970239.

YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis

Wei Su, Yingying Guo, Qianqian Wang, Lu Ma, Qing Zhang, Yuhan Zhang, Yiding Geng, Tongzhu Jin, Jiayu Guo, Ruoxuan Yang, Zhihui Niu, Lingxue Ren, Yan Wang, Zhiwei Ning, Wenyue Li, Wenxin He, Jian Sun, Tianyu Li, Zhixin Li, Hongli Shan, Haihai Liang

Exp Mol Med. 2024 Jul; 56(7): 1643–1654. Published online 2024 Jul 1. doi: 10.1038/s12276-024-01277-0

PMCID:: PMC11297023

Abstract Article PDF–8.1M

Select item 1125915910.

A fibronectin gradient remodels mixed-phase mesoderm

Min Zhu, Bin Gu, Evan C. Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M. Yung, Xin Chen, Kaiwen Zhang, Elizabeth K. Woolaver, Mikaela R. Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun, Sevan Hopyan

Sci Adv. 2024 Jul 19; 10(29): eadl6366. Published online 2024 Jul 19. doi: 10.1126/sciadv.adl6366

PMCID:: PMC11259159

Abstract Article PDF–6.7M

Select item 1116160111.

A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion

Antoine A. Khalil, Daan Smits, Peter D. Haughton, Thijs Koorman, Karin A. Jansen, Mathijs P. Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G. El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J. van Diest, Cathy B. Moelans, M. Guy Roukens, Sandra Tavares, Anne-Marie Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried. J. T. Zwartkruis, Patrick WB. Derksen, Johan de Rooij

Nat Commun. 2024; 15: 4866. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49230-z

PMCID:: PMC11161601

Abstract Article PDF–7.2M

Select item 1113995812.

Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling

Hanwen Li, Yingchuang Tang, Zixiang Liu, Kangwu Chen, Kai Zhang, Sihan Hu, Chun Pan, Huilin Yang, Bin Li, Hao Chen

Bone Res. 2024; 12: 34. Published online 2024 May 30. doi: 10.1038/s41413-024-00331-x

PMCID:: PMC11139958

Abstract Article PDF–8.1M

Select item 1113666613.

Hippo–YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass

Sungwoo Choi, Ju-Gyeong Kang, Yen T. H. Tran, Sun-Hye Jeong, Kun-Young Park, Hyemi Shin, Young Hoon Kim, Myungsun Park, Hahn Nahmgoong, Taejun Seol, Haeyon Jeon, Yeongmin Kim, Sanghee Park, Hee-joo Kim, Min-Seob Kim, Xiaoxu Li, Maroun Bou Sleiman, Eries Lee, Jinhyuk Choi, David Eisenbarth, Sang Heon Lee, Suhyeon Cho, David D. Moore, Johan Auwerx, Il-Young Kim, Jae Bum Kim, Jong-Eun Park, Dae-Sik Lim, Jae Myoung Suh

Nat Metab. 2024; 6(5): 847–860. Published online 2024 May 29. doi: 10.1038/s42255-024-01045-4

PMCID:: PMC11136666

Abstract Article PDF–18M

Select item 1110500414.

Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation

Eunae You, Panseon Ko, Jangho Jeong, Seula Keum, Jung-Woong Kim, Young-Jin Seo, Woo Keun Song, Sangmyung Rhee

Cell Mol Life Sci. 2020 Oct; 77(20): 4143–4161. Published online 2020 Jan 7. doi: 10.1007/s00018-019-03412-x

PMCID:: PMC11105004

Abstract Article PDF–4.1M

Select item 1109418915.

Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee

Nat Commun. 2024; 15: 4052. Published online 2024 May 14. doi: 10.1038/s41467-024-48179-3

Correction in:: Nat Commun. 2024; 15: 5623.

PMCID:: PMC11094189

Abstract Article PDF–8.2M

Select item 1102119616.

Competence for neural crest induction is controlled by hydrostatic pressure through Yap

Delan N. Alasaadi, Lucas Alvizi, Jonas Hartmann, Namid Stillman, Prachiti Moghe, Takashi Hiiragi, Roberto Mayor

Nat Cell Biol. 2024; 26(4): 530–541. Published online 2024 Mar 18. doi: 10.1038/s41556-024-01378-y

PMCID:: PMC11021196

Abstract Article PDF–8.6M

Select item 1101914117.

Nucleoporin93 limits Yap activity to prevent endothelial cell senescence

Tung D. Nguyen, Mihir K. Rao, Shaiva P. Dhyani, Justin M. Banks, Michael A. Winek, Julia Michalkiewicz, Monica Y. Lee

Aging Cell. 2024 Apr; 23(4): e14095. Published online 2024 Feb 13. doi: 10.1111/acel.14095

PMCID:: PMC11019141

Abstract Article PDF–35M

Select item 1100826818.

Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways

Yan Zhang, Huiwen Chen, Jinjin Wu, Abigail McVicar, Yilin Chen, Jiacan Su, Yi-Ping Li, Wei Chen

Int J Biol Sci. 2024; 20(6): 1965–1977. Published online 2024 Mar 11. doi: 10.7150/ijbs.90250

PMCID:: PMC11008268

Abstract Article PDF–16M

Select item 1099728919.

GRK2–YAP signaling is implicated in pulmonary arterial hypertension development

Peng Ye, Yunfei Deng, Yue Gu, Pengfei Liu, Jie Luo, Jiangqin Pu, Jingyu Chen, Yu Huang, Nanping Wang, Yong Ji, Shaoliang Chen

Chin Med J (Engl) 2024 Apr 5; 137(7): 846–858. Published online 2024 Jan 19. doi: 10.1097/CM9.0000000000002946

PMCID:: PMC10997289

Abstract Article PDF–13M

Select item 1096851120.

Hedgehog Signaling Controls Chondrogenesis and Ectopic Bone Formation via the Yap-Ihh Axis

Qian Cong, Yingzi Yang

Biomolecules. 2024 Mar; 14(3): 347. Published online 2024 Mar 14. doi: 10.3390/biom14030347

PMCID:: PMC10968511

Abstract Article PDF–3.9M

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