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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 85029502.

Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2

Cheryl van de Wetering, Allison M. Manuel, Mona Sharafi, Reem Aboushousha, Xi Qian, Cuixia Erickson, Maximilian MacPherson, Garrett Chan, Ian M. Adcock, Nazanin ZounematKermani, Florence Schleich, Renaud Louis, Eric Bohrnsen, Angelo D'Alessandro, Emiel F. Wouters, Niki L. Reynaert, Jianing Li, C. Roland Wolf, Colin J. Henderson, Lennart K.A. Lundblad, Matthew E. Poynter, Anne E. Dixon, Charles G. Irvin, Albert van der Vliet, Jos L. van der Velden, Yvonne M. Janssen-Heininger

Redox Biol. 2021 Nov; 47: 102160. Published online 2021 Oct 3. doi: 10.1016/j.redox.2021.102160

PMCID:: PMC8502950

Abstract Article PDF–6.9M

Select item 80331463.

Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex

Xiaonan Liu, Sara M Blazejewski, Sarah A Bennison, Kazuhito Toyo-oka

Hum Mol Genet. 2021 Jan 1; 30(1): 30–45. Published online 2021 Jan 12. doi: 10.1093/hmg/ddab003

PMCID:: PMC8033146

Abstract Article PDF–2.3M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74309925.

A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with KRAS and BRAF mutations

Yoshiro Niitsu, Yasushi Sato, Kunihiro Takanashi, Tsuyoshi Hayashi, Naoko Kubo-Birukawa, Fumiko Shimizu, Naoki Fujitani, Rai Shimoyama, Takehiro Kukitsu, Wataru Kurata, Yasuyuki Tashiro, Irving Listowsky

Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32): 19435–19445. Published online 2020 Jul 27. doi: 10.1073/pnas.2000361117

PMCID:: PMC7430992

Abstract Article PDF–1.9M

Select item 73756996.

Crotonaldehyde-induced Vascular Relaxation and Toxicity: Role of Endothelium and Transient Receptor Potential Ankyrin-1 (TRPA1)

L. Jin, G. Jagatheesan, J. Lynch, L. Guo, D.J. Conklin

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2020 Jul 1; 398: 115012. Published online 2020 Apr 19. doi: 10.1016/j.taap.2020.115012

Correction in:: Toxicol Appl Pharmacol. 2020 Jun 26 : 115114.

PMCID:: PMC7375699

Abstract Article PDF–863K

Select item 62931607.

Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis

Shubha Ghosh Dastidar, Ganapathy Jagatheesan, Petra Haberzettl, Jasmit Shah, Bradford G. Hill, Aruni Bhatnagar, Daniel J. Conklin

Am J Physiol Endocrinol Metab. 2018 Nov 1; 315(5): E1005–E1018. Published online 2018 Aug 28. doi: 10.1152/ajpendo.00345.2017

PMCID:: PMC6293160

Abstract Article

Select item 58682528.

S-Glutathionylation of estrogen receptor α affects dendritic cell function

Jie Zhang, Zhi-wei Ye, Wei Chen, Yefim Manevich, Shikhar Mehrotra, Lauren Ball, Yvonne Janssen-Heininger, Kenneth D. Tew, Danyelle M. Townsend

J Biol Chem. 2018 Mar 23; 293(12): 4366–4380. Published online 2018 Jan 26. doi: 10.1074/jbc.M117.814327

PMCID:: PMC5868252

Abstract Article PDF–2.2M

Select item 48544439.

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury

Daniel J. Conklin, Yiru Guo, Ganapathy Jagatheesan, Peter Kilfoil, Petra Haberzettl, Bradford G. Hill, Shahid P. Baba, Luping Guo, Karin Wetzelberger, Detlef Obal, D. Gregg Rokosh, Russell A. Prough, Sumanth D. Prabhu, Murugesan Velayutham, Jay L. Zweier, David Hoetker, Daniel W. Riggs, Sanjay Srivastava, Roberto Bolli, Aruni Bhatnagar

Circ Res. Author manuscript; available in PMC 2016 Aug 14.

Published in final edited form as: Circ Res. 2015 Aug 14; 117(5): 437–449. Published online 2015 Jul 13. doi: 10.1161/CIRCRESAHA.114.305518

PMCID:: PMC4854443

Abstract Article PDF–2.1M

Select item 466976010.

Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

J Pajaud, C Ribault, I Ben Mosbah, C Rauch, C Henderson, P Bellaud, C Aninat, P Loyer, F Morel, A Corlu

Cell Death Dis. 2015 Jan; 6(1): e1598. Published online 2015 Jan 15. doi: 10.1038/cddis.2014.562

PMCID:: PMC4669760

Abstract Article PDF–5.3M

Select item 443043411.

Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice

Daniel J. Conklin, Petra Haberzettl, Ganapathy Jagatheesan, Shahid Baba, Michael L. Merchant, Russell A. Prough, Jessica D. Williams, Sumanth D. Prabhu, Aruni Bhatnagar

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2015 Jun 1; 285(2): 136–148. Published online 2015 Apr 10. doi: 10.1016/j.taap.2015.03.029

PMCID:: PMC4430434

Abstract Article PDF–2.4M

Select item 416260612.

Glutathione S-Transferase P Influences Redox and Migration Pathways in Bone Marrow

Jie Zhang, Zhi-Wei Ye, Peng Gao, Leticia Reyes, Elizabeth E. Jones, Melissa Branham-O’Connor, Joe B. Blumer, Richard R. Drake, Yefim Manevich, Danyelle M. Townsend, Kenneth D. Tew

PLoS One. 2014; 9(9): e107478. Published online 2014 Sep 12. doi: 10.1371/journal.pone.0107478

Correction in:: PLoS One. 2015; 10(3): e0119266.

PMCID:: PMC4162606

Abstract Article PDF–1.1M

Select item 371068513.

Amniotic Fluid Activates the Nrf2/Keap1 Pathway to Repair an Epidermal Barrier Defect In Utero

Aaron J. Huebner, Daisy Dai, Maria Morasso, Edward E. Schmidt, Matthias Schäfer, Sabine Werner, Dennis R. Roop

Dev Cell. Author manuscript; available in PMC 2013 Jul 14.

Published in final edited form as: Dev Cell. 2012 Dec 11; 23(6): 1238–1246. doi: 10.1016/j.devcel.2012.11.002

PMCID:: PMC3710685

Abstract Article PDF–2.2M

Select item 336744114.

Olig2-dependent developmental fate switch of NG2 cells

Xiaoqin Zhu, Hao Zuo, Brady J. Maher, David R. Serwanski, Joseph J. LoTurco, Q. Richard Lu, Akiko Nishiyama

Development. 2012 Jul 1; 139(13): 2299–2307. doi: 10.1242/dev.078873

PMCID:: PMC3367441

Abstract Article

Select item 321810515.

Increased skin papilloma formation in mice lacking glutathione transferase GSTP

Colin J Henderson, Kenneth J Ritchie, Aileen McLaren, Probir Chakravarty, C. Roland Wolf

Cancer Res. Author manuscript; available in PMC 2012 May 15.

Published in final edited form as: Cancer Res. 2011 Nov 15; 71(22): 7048–7060. Published online 2011 Oct 5. doi: 10.1158/0008-5472.CAN-11-0882

PMCID:: PMC3218105

Abstract Article PDF–883K

Select item 319114316.

Humanizing π-Class Glutathione S-Transferase Regulation in a Mouse Model Alters Liver Toxicity in Response to Acetaminophen Overdose

Matthew P. Vaughn, Debika Biswal Shinohara, Nicole Castagna, Jessica L. Hicks, George Netto, Angelo M. De Marzo, Traci J. Speed, Zachery R. Reichert, Bernard Kwabi-Addo, Colin J. Henderson, C. Roland Wolf, Srinivasan Yegnasubramanian, William G. Nelson

PLoS One. 2011; 6(10): e25707. Published online 2011 Oct 11. doi: 10.1371/journal.pone.0025707