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Items: 1 to 20 of 39

1.
FZD6 Promotes Melanoma Cell Invasion but Not Proliferation by Regulating Canonical Wnt Signaling and Epithelial-Mesenchymal Transition
Bo Dong, Laura Simonson, Samantha Vold, Ethan Oldham, Lillian Barten, Nihal Ahmad, Hao Chang
J Invest Dermatol. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: J Invest Dermatol. 2023 Apr; 143(4): 621–629.e6. Published online 2022 Nov 9. doi: 10.1016/j.jid.2022.09.658
PMCID:
PMC10292634
AbstractArticlePDF–2.2M
2.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
3.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
4.
FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T‐cell acute lymphoblastic leukemia
Adriana Cassaro, Giovanni Grillo, Marco Notaro, Jessica Gliozzo, Ilaria Esposito, Gianluigi Reda, Alessandra Trojani, Giorgio Valentini, Barbara Di Camillo, Roberto Cairoli, Alessandro Beghini
Hematol Oncol. 2021 Aug; 39(3): 364–379. Published online 2021 Feb 16. doi: 10.1002/hon.2840
PMCID:
PMC8451758
AbstractArticlePDF–1.7M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
7.
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane
Molly M. Hannigan, Alyson M. Hoffman, J. Will Thompson, Tianli Zheng, Christopher V. Nicchitta
Mol Cell Proteomics. 2020 Nov; 19(11): 1826–1849. Published online 2020 Aug 10. doi: 10.1074/mcp.RA120.002228
PMCID:
PMC7664120
AbstractArticlePDF–4.8M
8.
Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects
Tian Tian, Yunping Lei, Yongyan Chen, Menuka Karki, Lei Jin, Richard H. Finnell, Linlin Wang, Aiguo Ren
Hum Genet. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Hum Genet. 2020 Oct; 139(10): 1299–1314. Published online 2020 Apr 30. doi: 10.1007/s00439-020-02172-0
PMCID:
PMC7487040
AbstractArticlePDF–1.5M
9.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
10.
NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6
Chunjie Xu, Guangang Tian, Chunhui Jiang, Hanbing Xue, Manzila Kuerbanjiang, Longci Sun, Lei Gu, Hong Zhou, Ye Liu, Zhigang Zhang, Qing Xu
Cell Death Dis. 2019 Mar; 10(3): 217. Published online 2019 Mar 4. doi: 10.1038/s41419-019-1467-7
PMCID:
PMC6399240
AbstractArticlePDF–4.7M
11.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
12.
A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia
Ceren Saygı, Yasemin Alanay, Uğur Sezerman, Aslı Yenenler, Nesrin Özören
BMC Med Genet. 2019; 20: 15. Published online 2019 Jan 14. doi: 10.1186/s12881-019-0746-6
PMCID:
PMC6332616
AbstractArticlePDF–1.9M
13.
Dishevelled enables casein kinase 1–mediated phosphorylation of Frizzled 6 required for cell membrane localization
Katerina Strakova, Maria Kowalski-Jahn, Tomas Gybel, Jana Valnohova, Vishnu M. Dhople, Jakub Harnos, Ondrej Bernatik, Ranjani Sri Ganji, Zbynek Zdrahal, Jan Mulder, Cecilia Lindskog, Vitezslav Bryja, Gunnar Schulte
J Biol Chem. 2018 Nov 30; 293(48): 18477–18493. Published online 2018 Oct 11. doi: 10.1074/jbc.RA118.004656
PMCID:
PMC6290145
AbstractArticlePDF–5.3M
14.
Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment
Jana Valnohova, Maria Kowalski-Jahn, Roger K. Sunahara, Gunnar Schulte
J Biol Chem. 2018 Nov 16; 293(46): 17875–17887. Published online 2018 Sep 19. doi: 10.1074/jbc.RA118.004763
PMCID:
PMC6240854
AbstractArticlePDF–3.1M
15.
LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation
Zhenzhen Chen, Yanfeng Gao, Lintong Yao, Yating Liu, Lan Huang, Zhongyi Yan, Wenshan Zhao, Pingping Zhu, Haibo Weng
Oncogene. 2018; 37(23): 3098–3112. Published online 2018 Mar 14. doi: 10.1038/s41388-018-0203-6
Correction in:
Oncogene. 2022; 41(34): 4115–4118.
PMCID:
PMC5992127
AbstractArticlePDF–8.2M
16.
Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics
Kun Han, Tingyuan Lang, Zhiqi Zhang, Yi Zhang, Yongning Sun, Zan Shen, Roger W. Beuerman, Lei Zhou, Daliu Min
Sci Rep. 2018; 8: 8537. Published online 2018 Jun 4. doi: 10.1038/s41598-018-26761-2
PMCID:
PMC5986741
AbstractArticlePDF–5.3M
17.
Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling
Julian Petersen, Shane C. Wright, David Rodríguez, Pierre Matricon, Noa Lahav, Aviv Vromen, Assaf Friedler, Johan Strömqvist, Stefan Wennmalm, Jens Carlsson, Gunnar Schulte
Nat Commun. 2017; 8: 226. Published online 2017 Aug 9. doi: 10.1038/s41467-017-00253-9
PMCID:
PMC5548745
AbstractArticlePDF–2.6M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
19.
Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer
Gabriele Corda, Gianluca Sala, Rossano Lattanzio, Manuela Iezzi, Michele Sallese, Giorgia Fragassi, Alessia Lamolinara, Hasan Mirza, Daniela Barcaroli, Sibylle Ermler, Elisabete Silva, Hemad Yasaei, Robert F Newbold, Paola Vagnarelli, Marcella Mottolese, Pier Giorgio Natali, Letizia Perracchio, Jelmar Quist, Anita Grigoriadis, Pierfrancesco Marra, Andrew N Tutt, Mauro Piantelli, Stefano Iacobelli, Vincenzo De Laurenzi, Arturo Sala
J Pathol. 2017 Feb; 241(3): 350–361. Published online 2016 Dec 29. doi: 10.1002/path.4841
PMCID:
PMC5248601
AbstractArticlePDF–2.0M
20.
Isolated recessive nail dysplasia caused by FZD6 mutations: report of three families and review of the literature
C. Kasparis, D. Reid, N. J. Wilson, V. Okur, C. Cole, C. D. Hansen, K. Bosse, R. C. Betz, M. Khan, F. J. D. Smith
Clin Exp Dermatol. 2016 Dec; 41(8): 884–889. Published online 2016 Oct 27. doi: 10.1111/ced.12934
PMCID:
PMC5132090
AbstractArticlePDF–574K

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