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Select item 111589791.

Organ microenvironment plays significant roles through Fas ligand in vaccine‐induced CD4⁺ T cell dependent suppression of tumor growth at the orthotopic site

Daisuke Sugiura, Kaori Denda‐Nagai, Kazuyoshi Takeda, Tatsuro Irimura

Cancer Sci. 2010 Sep; 101(9): 1965–1969. Published online 2010 May 27. doi: 10.1111/j.1349-7006.2010.01634.x

PMCID:: PMC11158979

Abstract Article PDF–515K

Select item 110939912.

Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality

Marie-Christine Albert, Iratxe Uranga-Murillo, Maykel Arias, Diego De Miguel, Natacha Peña, Antonella Montinaro, Ana Beatriz Varanda, Sebastian J. Theobald, Itziar Areso, Julia Saggau, Manuel Koch, Gianmaria Liccardi, Nieves Peltzer, Jan Rybniker, Ramón Hurtado-Guerrero, Pedro Merino, Marta Monzón, Juan J. Badiola, Roman Reindl-Schwaighofer, Rebeca Sanz-Pamplona, Alberto Cebollada-Solanas, Zsolt Megyesfalvi, Balazs Dome, Maria Secrier, Boris Hartmann, Michael Bergmann, Julián Pardo, Henning Walczak

Cell Death Differ. 2024 May; 31(5): 544–557. Published online 2024 Mar 21. doi: 10.1038/s41418-024-01278-6

PMCID:: PMC11093991

Abstract Article PDF–6.6M

Select item 110373263.

Antitumor activity exhibited by Fas ligand (CD95L) overexpressed on lymphoid cells against Fas⁺ tumor cells

Motomu Shimizu, Yasutaka Takeda, Hideo Yagita, Takayuki Yoshimoto, Akio Matsuzawa

Cancer Immunol Immunother. 1998 Oct; 47(3): 143–148. doi: 10.1007/s002620050514

PMCID:: PMC11037326

Abstract Article PDF–189K

Select item 110371894.

CD95 Ligand expression enhances growth of murine renal cell carcinoma in vivo

Hiroaki Nishimatsu, Takumi Takeuchi, Tetsuo Ueki, Takahiro Kajiwara, Nobuo Moriyama, Toshimitsu Ishida, Baoxing Li, Tadao Kakizoe, Tadaichi Kitamura

Cancer Immunol Immunother. 1999 Apr; 48(1): 56–61. doi: 10.1007/s002620050548

PMCID:: PMC11037189

Abstract Article PDF–453K

Select item 109468455.

FasL is a catabolic factor in alveolar bone homeostasis

Karol Alí Apaza Alccayhuaman, Patrick Heimel, Jung Seok Lee, Stefan Tangl, Ulrike Kuchler, Julie Marchesan, Layla Panahipour, Stefan Lettner, Eva Matalová, Reinhard Gruber

J Clin Periodontol. 2023 Mar; 50(3): 396–405. Published online 2022 Nov 25. doi: 10.1111/jcpe.13750

PMCID:: PMC10946845

Abstract Article PDF–5.7M

Select item 105473006.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 97229987.

CRISPR/Cas9-mediated abrogation of CD95L/CD95 signaling-induced glioma cell growth and immunosuppression increases survival in murine glioma models

Clara Quijano-Rubio, Manuela Silginer, Michael Weller

J Neurooncol. 2022; 160(2): 299–310. Published online 2022 Nov 10. doi: 10.1007/s11060-022-04137-x

PMCID:: PMC9722998

Abstract Article PDF–3.8M

Select item 88226208.

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

Daniel S. Simpson, Jiyi Pang, Ashley Weir, Isabella Y. Kong, Melanie Fritsch, Maryam Rashidi, James P. Cooney, Kathryn C. Davidson, Mary Speir, Tirta M. Djajawi, Sebastian Hughes, Liana Mackiewicz, Merle Dayton, Holly Anderton, Marcel Doerflinger, Yexuan Deng, Allan Shuai Huang, Stephanie A. Conos, Hazel Tye, Seong H. Chow, Arfatur Rahman, Raymond S. Norton, Thomas Naderer, Sandra E. Nicholson, Gaetan Burgio, Si Ming Man, Joanna R. Groom, Marco J. Herold, Edwin D. Hawkins, Kate E. Lawlor, Andreas Strasser, John Silke, Marc Pellegrini, Hamid Kashkar, Rebecca Feltham, James E. Vince

Immunity. 2022 Mar 8; 55(3): 423–441.e9. Published online 2022 Feb 8. doi: 10.1016/j.immuni.2022.01.003

PMCID:: PMC8822620

Abstract Article PDF–6.5M

Select item 87450659.

E2f2 Attenuates Apoptosis of Activated T Lymphocytes and Protects from Immune-Mediated Injury through Repression of Fas and FasL

Noor Mustafa, Jone Mitxelena, Arantza Infante, Olatz Zenarruzabeitia, Ainhoa Eriz, Ainhoa Iglesias-Ara, Ana M. Zubiaga

Int J Mol Sci. 2022 Jan; 23(1): 311. Published online 2021 Dec 28. doi: 10.3390/ijms23010311

PMCID:: PMC8745065

Abstract Article PDF–5.2M

Select item 843734210.

Fas/FasL Contributes to HSV-1 Brain Infection and Neuroinflammation

Malgorzata Krzyzowska, Andrzej Kowalczyk, Katarzyna Skulska, Karolina Thörn, Kristina Eriksson

Front Immunol. 2021; 12: 714821. Published online 2021 Aug 30. doi: 10.3389/fimmu.2021.714821

PMCID:: PMC8437342

Abstract Article PDF–3.7M

Select item 825725511.

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

Dongjin Jeong, Hye Sung Kim, Hye Young Kim, Min Jueng Kang, Hyeryeon Jung, Yumi Oh, Donghyun Kim, Jaemoon Koh, Sung-Yup Cho, Yoon Kyung Jeon, Eun Bong Lee, Seung Hyo Lee, Eui-Cheol Shin, Ho Min Kim, Eugene C Yi, Doo Hyun Chung

eLife. 2021; 10: e48840. Published online 2021 Jul 5. doi: 10.7554/eLife.48840

PMCID:: PMC8257255

Abstract Article PDF–3.9M

Select item 820066912.

FasL Is Required for Osseous Healing in Extraction Sockets in Mice

Karol Alí Apaza Alccayhuaman, Patrick Heimel, Jung-Seok Lee, Stefan Tangl, Franz J. Strauss, Alexandra Stähli, Eva Matalová, Reinhard Gruber

Front Immunol. 2021; 12: 678873. Published online 2021 May 31. doi: 10.3389/fimmu.2021.678873

PMCID:: PMC8200669

Abstract Article PDF–6.0M

Select item 802457013.

Fas/FasL Signaling Regulates CD8 Expression During Exposure to Self-Antigens

Giovanna Flores-Mendoza, Noé Rodríguez-Rodríguez, Rosa M. Rubio, Iris K. Madera-Salcedo, Florencia Rosetti, José C. Crispín

Front Immunol. 2021; 12: 635862. Published online 2021 Mar 24. doi: 10.3389/fimmu.2021.635862

PMCID:: PMC8024570

Abstract Article PDF–1.9M

Select item 769457614.

Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

Raud Razzaghi, Shreya Agarwal, Nikita Kotlov, Olga Plotnikova, Krystle Nomie, Da Wei Huang, George W. Wright, Grace A. Smith, Moyi Li, Katsuyoshi Takata, Maryam Yamadi, Chen Yao, John J. O’Shea, James D. Phelan, Stefania Pittaluga, David W. Scott, Jagan R. Muppidi

J Exp Med. 2021 Mar 1; 218(3): e20201173. Published online 2020 Nov 25. doi: 10.1084/jem.20201173

PMCID:: PMC7694576

Abstract Article PDF–6.4M

Select item 679325115.

Perforin-Dependent Neurologic Injury in a Viral Model of Multiple Sclerosis

Paul D. Murray, Dorian B. McGavern, Xiaoqi Lin, M. Kariuki Njenga, Julian Leibowitz, Larry R. Pease, Moses Rodriguez

J Neurosci. 1998 Sep 15; 18(18): 7306–7314. doi: 10.1523/JNEUROSCI.18-18-07306.1998

PMCID:: PMC6793251

Abstract Article PDF–1.0M

Select item 677664916.

IL-6-driven FasL promotes NF-κBp65/PUMA-mediated apoptosis in portal hypertensive gastropathy

Siwei Tan, Minyi Xu, Bilun Ke, Yu Lu, Huiling Liu, Jie Jiang, Bin Wu

Cell Death Dis. 2019 Oct; 10(10): 748. Published online 2019 Oct 3. doi: 10.1038/s41419-019-1954-x

PMCID:: PMC6776649

Abstract Article PDF–7.0M

Select item 676289217.

β-Amyloid Induces Neuronal Apoptosis Via a Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the Induction of Fas Ligand

Yoshiyuki Morishima, Yukiko Gotoh, Janine Zieg, Tamera Barrett, Hiromichi Takano, Richard Flavell, Roger J. Davis, Yasufumi Shirasaki, Michael E. Greenberg

J Neurosci. 2001 Oct 1; 21(19): 7551–7560. doi: 10.1523/JNEUROSCI.21-19-07551.2001

PMCID:: PMC6762892

Abstract Article PDF–735K

Select item 675835418.

Upregulation of the Fas Receptor Death-Inducing Signaling Complex after Traumatic Brain Injury in Mice and Humans

Jianhua Qiu, Michael J. Whalen, Pedro Lowenstein, Gary Fiskum, Brenda Fahy, Ribal Darwish, Bizhan Aarabi, Junying Yuan, Michael A. Moskowitz

J Neurosci. 2002 May 1; 22(9): 3504–3511. doi: 10.1523/JNEUROSCI.22-09-03504.2002

PMCID:: PMC6758354

Abstract Article PDF–445K

Select item 675513219.

Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice

Prerak M. Trivedi, Stacey Fynch, Lucy M. Kennedy, Jonathan Chee, Balasubramanian Krishnamurthy, Lorraine A. O’Reilly, Andreas Strasser, Thomas W. H. Kay, Helen E. Thomas

Cell Death Discov. 2019; 5: 136. Published online 2019 Sep 23. doi: 10.1038/s41420-019-0217-z

PMCID:: PMC6755132

Abstract Article PDF–673K

Select item 672528520.

Adult Motor Neuron Apoptosis Is Mediated by Nitric Oxide and Fas Death Receptor Linked by DNA Damage and p53 Activation

Lee J. Martin, Kevin Chen, Zhiping Liu

J Neurosci. 2005 Jul 6; 25(27): 6449–6459. doi: 10.1523/JNEUROSCI.0911-05.2005

PMCID:: PMC6725285

Abstract Article PDF–774K

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