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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 59025332.

Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk

Claudia Dalke, Frauke Neff, Savneet Kaur Bains, Scott Bright, Deborah Lord, Peter Reitmeir, Ute Rößler, Daniel Samaga, Kristian Unger, Herbert Braselmann, Florian Wagner, Matthias Greiter, Maria Gomolka, Sabine Hornhardt, Sarah Kunze, Stefan J. Kempf, Lillian Garrett, Sabine M. Hölter, Wolfgang Wurst, Michael Rosemann, Omid Azimzadeh, Soile Tapio, Michaela Aubele, Fabian Theis, Christoph Hoeschen, Predrag Slijepcevic, Munira Kadhim, Michael Atkinson, Horst Zitzelsberger, Ulrike Kulka, Jochen Graw

Radiat Environ Biophys. 2018; 57(2): 99–113. Published online 2018 Jan 11. doi: 10.1007/s00411-017-0728-z

PMCID:: PMC5902533

Abstract Article PDF–3.5M

Select item 55561823.

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

Marjolein P. Baar, Renata M.C. Brandt, Diana A. Putavet, Julian D.D. Klein, Kasper W.J. Derks, Benjamin R. M. Bourgeois, Sarah Stryeck, Yvonne Rijksen, Hester van Willigenburg, Danny A. Feijtel, Ingrid van der Pluijm, Jeroen Essers, Wiggert A. van Cappellen, Wilfred F.J. van IJcken, Adriaan B. Houtsmuller, Joris Pothof, Ron W.F. de Bruin, Tobias Madl, Jan H.J. Hoeijmakers, Judith Campisi, Peter L.J. de Keizer

Cell. Author manuscript; available in PMC 2018 Mar 23.

Published in final edited form as: Cell. 2017 Mar 23; 169(1): 132–147.e16. doi: 10.1016/j.cell.2017.02.031

PMCID:: PMC5556182

Abstract Article PDF–1.6M

Select item 44239724.

New Mutation in the Mouse Xpd/Ercc2 Gene Leads to Recessive Cataracts

Sarah Kunze, Claudia Dalke, Helmut Fuchs, Matthias Klaften, Ute Rössler, Sabine Hornhardt, Maria Gomolka, Oliver Puk, Sibylle Sabrautzki, Ulrike Kulka, Martin Hrabě de Angelis, Jochen Graw

PLoS One. 2015; 10(5): e0125304. Published online 2015 May 7. doi: 10.1371/journal.pone.0125304

PMCID:: PMC4423972

Abstract Article PDF–17M

Select item 42076665.

Dynamic Partnership between TFIIH, PGC-1α and SIRT1 Is Impaired in Trichothiodystrophy

Hussein Traboulsi, Serena Davoli, Philippe Catez, Jean-Marc Egly, Emmanuel Compe

PLoS Genet. 2014 Oct; 10(10): e1004732. Published online 2014 Oct 23. doi: 10.1371/journal.pgen.1004732

PMCID:: PMC4207666

Abstract Article PDF–2.2M

Select item 37994376.

XPD-dependent activation of apoptosis in response to triplex-induced DNA damage

Meetu Kaushik Tiwari, Faye A. Rogers

Nucleic Acids Res. 2013 Oct; 41(19): 8979–8994. Published online 2013 Aug 2. doi: 10.1093/nar/gkt670

PMCID:: PMC3799437

Abstract Article PDF–17M

Select item 35724107.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 34337798.

Generation of DNA single-strand displacement by compromised nucleotide excision repair

Camille Godon, Sophie Mourgues, Julie Nonnekens, Amandine Mourcet, Fréderic Coin, Wim Vermeulen, Pierre-Olivier Mari, Giuseppina Giglia-Mari

EMBO J. 2012 Aug 29; 31(17): 3550–3563. Published online 2012 Aug 3. doi: 10.1038/emboj.2012.193

PMCID:: PMC3433779

Abstract Article PDF–2.1M

Select item 34307279.

Nucleotide Excision DNA Repair is Associated with Age-Related Vascular Dysfunction

Matej Durik, Maryam Kavousi, Ingrid van der Pluijm, Aaron Isaacs, Caroline Cheng, Koen Verdonk, Annemarieke E. Loot, Hisko Oeseburg, Usha Musterd-Bhaggoe, Frank Leijten, Richard van Veghel, Rene de Vries, Goran Rudez, Renata Brandt, Yanto R. Ridwan, Elza D. van Deel, Martine de Boer, Dennie Tempel, Ingrid Fleming, Gary F. Mitchell, Germaine C. Verwoert, Kirill V. Tarasov, Andre G. Uitterlinden, Albert Hofman, Henricus J. Duckers, Cornelia M. van Duijn, Ben A. Oostra, Jacqueline C.M. Witteman, Dirk J. Duncker, A.H. Jan Danser, Jan H. Hoeijmakers, Anton J.M. Roks

Circulation. Author manuscript; available in PMC 2013 Jul 24.

Published in final edited form as: Circulation. 2012 Jul 24; 126(4): 468–478. Published online 2012 Jun 15. doi: 10.1161/CIRCULATIONAHA.112.104380

PMCID:: PMC3430727

Abstract Article PDF–1.9M

Select item 332364710.

Claudia Nicolaije, Karin E. M. Diderich, S. M. Botter, Matthias Priemel, Jan H. Waarsing, Judd S. Day, Renata M. C. Brandt, Arndt F. Schilling, Harrie Weinans, Bram C. Van der Eerden, Gijsbertus T. J. van der Horst, Jan H. J. Hoeijmakers, Johannes P. T. M. van Leeuwen

PLoS One. 2012; 7(4): e35246. Published online 2012 Apr 10. doi: 10.1371/journal.pone.0035246

PMCID:: PMC3323647

Abstract Article PDF–1.0M

Select item 323422011.

Dick Jaarsma, Ingrid van der Pluijm, Monique C. de Waard, Elize D. Haasdijk, Renata Brandt, Marcel Vermeij, Yvonne Rijksen, Alex Maas, Harry van Steeg, Jan H. J. Hoeijmakers, Gijsbertus T. J. van der Horst

PLoS Genet. 2011 Dec; 7(12): e1002405. Published online 2011 Dec 8. doi: 10.1371/journal.pgen.1002405

PMCID:: PMC3234220

Abstract Article PDF–1.2M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015113.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 264382515.

An Xpb Mouse Model for Combined Xeroderma Pigmentosum and Cockayne Syndrome Reveals Progeroid Features upon Further Attenuation of DNA Repair

Jaan-Olle Andressoo, Geert Weeda, Jan de Wit, James R. Mitchell, Rudolf B. Beems, Harry van Steeg, Gijsbertus T. J. van der Horst, Jan H. Hoeijmakers

Mol Cell Biol. 2009 Mar; 29(5): 1276–1290. Published online 2008 Dec 29. doi: 10.1128/MCB.01229-08

PMCID:: PMC2643825

Abstract Article PDF–1.4M

Select item 239650616.

Homeostatic Imbalance between Apoptosis and Cell Renewal in the Liver of Premature Aging Xpd^TTD Mice

Jung Yoon Park, Mi-Ook Cho, Shanique Leonard, Brent Calder, I. Saira Mian, Woo Ho Kim, Susan Wijnhoven, Harry van Steeg, James Mitchell, Gijsbertus T. J. van der Horst, Jan Hoeijmakers, Pinchas Cohen, Jan Vijg, Yousin Suh

PLoS One. 2008; 3(6): e2346. Published online 2008 Jun 11. doi: 10.1371/journal.pone.0002346

PMCID:: PMC2396506

Abstract Article PDF–338K

Select item 221230917.

Hypermutation of Immunoglobulin Genes in Memory B Cells of DNA Repair–deficient Mice

Heinz Jacobs, Yosho Fukita, Gijsbertus T.J. van der Horst, Jan de Boer, Geert Weeda, Jeroen Essers, Niels de Wind, Bevin P. Engelward, Leona Samson, Sjef Verbeek, Josiane Ménissier de Murcia, Gilbert de Murcia, Hein t e Riele, Klaus Rajewsky

J Exp Med. 1998 Jun 1; 187(11): 1735–1743. doi: 10.1084/jem.187.11.1735

PMCID:: PMC2212309

Abstract Article PDF–169K

Select item 169894618.

Adaptive Stress Response in Segmental Progeria Resembles Long-Lived Dwarfism and Calorie Restriction in Mice

Marieke van de Ven, Jaan-Olle Andressoo, Valerie B Holcomb, Marieke von Lindern, Willeke M. C Jong, Chris I. De Zeeuw, Yousin Suh, Paul Hasty, Jan H. J Hoeijmakers, Gijsbertus T. J van der Horst, James R Mitchell

PLoS Genet. 2006 Dec; 2(12): e192. Prepublished online 2006 Oct 2. Published online 2006 Dec 15. doi: 10.1371/journal.pgen.0020192

Correction in:: PLoS Genet. 2008 Oct; 4(10): 10.1371/annotation/31502636-9bdf-4cb1-b995-4a30a607e316.

PMCID:: PMC1698946

Abstract Article PDF–818K

Select item 168509719.

The physicochemical properties of hair in the BIDS syndrome.

H P Baden, C E Jackson, L Weiss, K Jimbow, L Lee, J Kubilus, R J Gold

Am J Hum Genet. 1976 Sep; 28(5): 514–521.

PMCID:: PMC1685097

Summary Page Browse PDF–1.3M

Select item 158441620.

Rescue of Progeria in Trichothiodystrophy by Homozygous Lethal Xpd Alleles

Jaan-Olle Andressoo, Judith Jans, Jan de Wit, Frederic Coin, Deborah Hoogstraten, Marieke van de Ven, Wendy Toussaint, Jan Huijmans, H. Bing Thio, Wibeke J van Leeuwen, Jan de Boer, Jean-Marc Egly, Jan H. J Hoeijmakers, Gijsbertus T. J van der Horst, James R Mitchell

PLoS Biol. 2006 Oct; 4(10): e322. Published online 2006 Oct 3. doi: 10.1371/journal.pbio.0040322

PMCID:: PMC1584416

Abstract Article PDF–794K

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