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Items: 1 to 20 of 52

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems
Charlotte Decourt, Julia Schaeffer, Beatrice Blot, Antoine Paccard, Blandine Excoffier, Mario Pende, Homaira Nawabi, Stephane Belin
PLoS Biol. 2023 Apr; 21(4): e3002044. Published online 2023 Apr 17. doi: 10.1371/journal.pbio.3002044
PMCID:
PMC10109519
AbstractArticlePDF–5.3M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division
Martina Bonucci, Nicolas Kuperwasser, Serena Barbe, Vonda Koka, Delphine de Villeneuve, Chi Zhang, Nishit Srivastava, Xiaoying Jia, Matthew P. Stokes, Frank Bienaimé, Virginie Verkarre, Jean Baptiste Lopez, Fanny Jaulin, Marco Pontoglio, Fabiola Terzi, Benedicte Delaval, Matthieu Piel, Mario Pende
Nat Commun. 2020; 11: 3200. Published online 2020 Jun 24. doi: 10.1038/s41467-020-16978-z
PMCID:
PMC7314806
AbstractArticlePDF–6.6M
5.
Senescent phenotype induced by p90RSK-NRF2 signaling sensitizes monocytes and macrophages to oxidative stress in HIV+ individuals: implications for atherogenesis
Meera V. Singh, Sivareddy Kotla, Nhat-Tu Le, Kyung Ae Ko, Kyung-Sun Heo, Yin Wang, Yuka Fujii, Hang Thi Vu, Elena McBeath, Tamlyn N. Thomas, Young Jin Gi, Yunting Tao, Jan L. Medina, Jack Taunton, Nancy Carson, Vikram Dogra, Marvin M. Doyley, Alicia Tyrell, Wang Lu, Xing Qiu, Nicole E. Stirpe, Kathleen J. Gates, Christine Hurley, Keigi Fujiwara, Sanjay B. Maggirwar, Giovanni Schifitto, Jun-ichi Abe
Circulation. Author manuscript; available in PMC 2020 Feb 26.
Published in final edited form as: Circulation. 2019 Feb 26; 139(9): 1199–1216. doi: 10.1161/CIRCULATIONAHA.118.036232
PMCID:
PMC6957233
AbstractArticlePDF–2.4M
6.
Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases
Ruhcha V. Sutavani, Iain R. Phair, Rebecca Barker, Alison McFarlane, Natalia Shpiro, Stuart Lang, Andrew Woodland, J. Simon C. Arthur
J Biol Chem. 2018 Feb 16; 293(7): 2302–2317. Published online 2017 Dec 11. doi: 10.1074/jbc.M117.805424
PMCID:
PMC5818195
AbstractArticlePDF–3.9M
7.
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras
Tim Wang, Haiyan Yu, Nicholas W. Hughes, Bingxu Liu, Arek Kendirli, Klara Klein, Walter W. Chen, Eric S. Lander, David M. Sabatini
Cell. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: Cell. 2017 Feb 23; 168(5): 890–903.e15. Published online 2017 Feb 2. doi: 10.1016/j.cell.2017.01.013
PMCID:
PMC5445660
AbstractArticlePDF–2.2M
8.
Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex
Lei Xing, Rylan S Larsen, George Reed Bjorklund, Xiaoyan Li, Yaohong Wu, Benjamin D Philpot, William D Snider, Jason M Newbern
eLife. 2016; 5: e11123. Published online 2016 Feb 5. doi: 10.7554/eLife.11123
PMCID:
PMC4758957
AbstractArticlePDF–9.6M
9.
The PDK1–Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning
Rossana Zaru, Stephen P. Matthews, Alexander J. Edgar, Alan R. Prescott, Diego Gomez-Nicola, André Hanauer, Colin Watts
J Immunol. 2015 Nov 1; 195(9): 4264–4272. Published online 2015 Sep 23. doi: 10.4049/jimmunol.1501520
PMCID:
PMC4640173
AbstractArticlePDF–1.8M
10.
The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft
Immunity. Author manuscript; available in PMC 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017
PMCID:
PMC4618086
AbstractArticlePDF–2.2M
11.
Structural and Functional Basis for p38-MK2-Activated Rsk Signaling in Toll-Like Receptor-Stimulated Dendritic Cells
Rossana Zaru, Alexander J. Edgar, André Hanauer, Colin Watts
Mol Cell Biol. 2015 Jan; 35(1): 132–140. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00773-14
PMCID:
PMC4295372
AbstractArticlePDF–1.3M
12.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
13.
IL-6 Impairs Myogenic Differentiation by Downmodulation of p90RSK/eEF2 and mTOR/p70S6K Axes, without Affecting AKT Activity
Michele Pelosi, Manuela De Rossi, Laura Barberi, Antonio Musarò
Biomed Res Int. 2014; 2014: 206026. Published online 2014 May 21. doi: 10.1155/2014/206026
PMCID:
PMC4055274
AbstractArticlePDF–2.2M
14.
Quetiapine and aripiprazole signal differently to ERK, p90RSK and c-Fos in mouse frontal cortex and striatum: role of the EGF receptor
Avril Pereira, Betty Zhang, Peter Malcolm, Anthony Sugiharto-Winarno, Suresh Sundram
BMC Neurosci. 2014; 15: 30. Published online 2014 Feb 20. doi: 10.1186/1471-2202-15-30
PMCID:
PMC3936900
AbstractArticlePDF–1.4M
15.
Interactions between the Regulatory Subunit of Type I Protein Kinase A and p90 Ribosomal S6 Kinase1 Regulate Cardiomyocyte Apoptosis
Xianlong Gao, Brian Lin, Sakthivel Sadayappan, Tarun B. Patel
Mol Pharmacol. 2014 Feb; 85(2): 357–367. Published online 2014 Feb. doi: 10.1124/mol.113.090613
PMCID:
PMC3913359
AbstractArticlePDF–1.7M
16.
RSK2 Is a Modulator of Craniofacial Development
Virginie Laugel-Haushalter, Marie Paschaki, Pauline Marangoni, Coralie Pilgram, Arnaud Langer, Thibaut Kuntz, Julie Demassue, Supawich Morkmued, Philippe Choquet, André Constantinesco, Fabien Bornert, Matthieu Schmittbuhl, Solange Pannetier, Laurent Viriot, André Hanauer, Pascal Dollé, Agnès Bloch-Zupan
PLoS One. 2014; 9(1): e84343. Published online 2014 Jan 8. doi: 10.1371/journal.pone.0084343
PMCID:
PMC3885557
AbstractArticlePDF–2.5M
17.
A Crucial Role for p90RSK-Mediated Reduction of ERK5 Transcriptional Activity in Endothelial Dysfunction and Atherosclerosis
Nhat-Tu Le, Kyung-Sun Heo, Yuichiro Takei, Hakjoo Lee, Chang-Hoon Woo, Eugene Chang, Carolyn McClain, Cheryl Hurley, Xin Wang, Faqian Li, Haodong Xu, Craig Morrell, Mark A. Sullivan, Michael S. Cohen, Iana M. Serafimova, Jack Taunton, Keigi Fujiwara, Jun-ichi Abe
Circulation. Author manuscript; available in PMC 2014 Jan 29.
Published in final edited form as: Circulation. 2013 Jan 29; 127(4): 486–499. Published online 2012 Dec 14. doi: 10.1161/CIRCULATIONAHA.112.116988
PMCID:
PMC3574639
AbstractArticlePDF–6.3M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Complete Dependence on IRAK4 Kinase Activity in TLR2, but Not TLR4, Signaling Pathways Underlies Decreased Cytokine Production and Increased Susceptibility to Streptococcus pneumoniae Infection in IRAK4 Kinase-Inactive Mice
Meghan E. Pennini, Darren J. Perkins, Andres M. Salazar, Michael Lipsky, Stefanie N. Vogel
J Immunol. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: J Immunol. 2013 Jan 1; 190(1): 307–316. Published online 2012 Dec 3. doi: 10.4049/jimmunol.1201644
PMCID:
PMC3535482
AbstractArticlePDF–1.0M
20.
ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase
Gerta Hoxhaj, Ayaz Najafov, Rachel Toth, David G. Campbell, Alan R. Prescott, Carol MacKintosh
J Cell Sci. 2012 Oct 1; 125(19): 4662–4675. doi: 10.1242/jcs.110296
Correction in:
J Cell Sci. 2022 Mar 15; 135(6): jcs259936.
PMCID:
PMC3500867
AbstractArticle

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