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Items: 1 to 20 of 105

1.
De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
Luca F. Sandor, Joon B. Huh, Peter Benko, Toru Hiraga, Szilard Poliska, Csaba Dobo-Nagy, Joanna P. Simpson, Natalie Z.M. Homer, Bidesh Mahata, David S. Gyori
Cell Rep. 2024 Mar 26; 43(3): 113936. Published online 2024 Mar 13. doi: 10.1016/j.celrep.2024.113936
PMCID:
PMC10995766
AbstractArticle
2.
Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development
Yongzhen Lai, Yan Guo, Caiyu Liao, Chuanqing Mao, Jing Liu, Chengyan Ren, Wen Yang, Lin Luo, Weihui Chen
Sci Rep. 2023; 13: 15170. Published online 2023 Sep 13. doi: 10.1038/s41598-023-42423-4
PMCID:
PMC10499879
AbstractArticlePDF–6.8M
3.
M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
Natalia Torow, Ronghui Li, Thomas Charles Adrian Hitch, Clemens Mingels, Shahed Al Bounny, Niels van Best, Eva-Lena Stange, Britta Simons, Tiago Maié, Lennart Rüttger, Narasimha Murthy Keshava Prasad Gubbi, Darryl Adelaide Abbott, Adam Benabid, Michael Gadermayr, Solveig Runge, Nicole Treichel, Dorit Merhof, Stephan Patrick Rosshart, Nico Jehmlich, Timothy Wesley Hand, Martin von Bergen, Felix Heymann, Oliver Pabst, Thomas Clavel, Frank Tacke, Hugues Lelouard, Ivan Gesteira Costa, Mathias Walter Hornef
Immunity. 2023 Jun 13; 56(6): 1220–1238.e7. doi: 10.1016/j.immuni.2023.04.002
PMCID:
PMC10262694
AbstractArticle
4.
Neuronal signal regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina
Danye Jiang, Courtney A. Burger, Viktor Akhanov, Justine H. Liang, Robert D. Mackin, Nicholas E. Albrecht, Pilar Andrade, Dorothy P. Schafer, Melanie A. Samuel
Immunity. Author manuscript; available in PMC 2023 Dec 13.
Published in final edited form as: Immunity. 2022 Dec 13; 55(12): 2318–2335.e7. Published online 2022 Nov 14. doi: 10.1016/j.immuni.2022.10.018
PMCID:
PMC9772037
AbstractArticlePDF–5.4M
5.
A20 controls RANK‐dependent osteoclast formation and bone physiology
Arne Martens, Pieter Hertens, Dario Priem, Vagelis Rinotas, Theodore Meletakos, Meropi Gennadi, Lisette Van Hove, Els Louagie, Julie Coudenys, Amélie De Muynck, Djoere Gaublomme, Mozes Sze, Jolanda van Hengel, Leen Catrysse, Esther Hoste, Jeffrey D Zajac, Rachel A Davey, Luc Van Hoorebeke, Tino Hochepied, Mathieu J M Bertrand, Marietta Armaka, Dirk Elewaut, Geert van Loo
EMBO Rep. 2022 Dec; 23(12): e55233. Published online 2022 Oct 4. doi: 10.15252/embr.202255233
PMCID:
PMC9724664
AbstractArticlePDF–3.0M
6.
Senescent preosteoclast secretome promotes metabolic syndrome associated osteoarthritis through cyclooxygenase 2
Weiping Su, Guanqiao Liu, Bahram Mohajer, Jiekang Wang, Alena Shen, Weixin Zhang, Bin Liu, Ali Guermazi, Peisong Gao, Xu Cao, Shadpour Demehri, Mei Wan
eLife. 2022; 11: e79773. Published online 2022 Jul 26. doi: 10.7554/eLife.79773
PMCID:
PMC9365389
AbstractArticlePDF–24M
7.
Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation
Atsushi Arai, Sol Kim, Vadim Goldshteyn, Terresa Kim, No-Hee Park, Cun-Yu Wang, Reuben Kim
J Bone Miner Res. Author manuscript; available in PMC 2022 Aug 3.
Published in final edited form as: J Bone Miner Res. 2019 Sep; 34(9): 1753–1766. Published online 2019 Jul 30. doi: 10.1002/jbmr.3756
PMCID:
PMC9346192
AbstractArticlePDF–1.7M
8.
CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling
Abdouramane Camara, Alice C. Lavanant, Jun Abe, Henri Lee Desforges, Yannick O. Alexandre, Erika Girardi, Zinaida Igamberdieva, Kenichi Asano, Masato Tanaka, Thomas Hehlgans, Klaus Pfeffer, Sébastien Pfeffer, Scott N. Mueller, Jens V. Stein, Christopher G. Mueller
Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2108540119. Published online 2022 Jan 14. doi: 10.1073/pnas.2108540119
PMCID:
PMC8784161
AbstractArticlePDF–2.7M
9.
Osteoclasts adapt to physioxia perturbation through DNA demethylation
Keizo Nishikawa, Shigeto Seno, Toshitada Yoshihara, Ayako Narazaki, Yuki Sugiura, Reito Shimizu, Junichi Kikuta, Reiko Sakaguchi, Norio Suzuki, Norihiko Takeda, Hiroaki Semba, Masamichi Yamamoto, Daisuke Okuzaki, Daisuke Motooka, Yasuhiro Kobayashi, Makoto Suematsu, Haruhiko Koseki, Hideo Matsuda, Masayuki Yamamoto, Seiji Tobita, Yasuo Mori, Masaru Ishii
EMBO Rep. 2021 Dec 6; 22(12): e53035. Published online 2021 Oct 18. doi: 10.15252/embr.202153035
PMCID:
PMC8647016
AbstractArticlePDF–2.6M
10.
Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells
Clara Gómez-Aleza, Bastien Nguyen, Guillermo Yoldi, Marina Ciscar, Alexandra Barranco, Enrique Hernández-Jiménez, Marion Maetens, Roberto Salgado, Maria Zafeiroglou, Pasquale Pellegrini, David Venet, Soizic Garaud, Eva M. Trinidad, Sandra Benítez, Peter Vuylsteke, Laura Polastro, Hans Wildiers, Philippe Simon, Geoffrey Lindeman, Denis Larsimont, Gert Van den Eynden, Chloé Velghe, Françoise Rothé, Karen Willard-Gallo, Stefan Michiels, Purificación Muñoz, Thierry Walzer, Lourdes Planelles, Josef Penninger, Hatem A. Azim, Jr, Sherene Loi, Martine Piccart, Christos Sotiriou, Eva González-Suárez
Nat Commun. 2020; 11: 6335. Published online 2020 Dec 10. doi: 10.1038/s41467-020-20138-8
PMCID:
PMC7728758
AbstractArticlePDF–2.8M
11.
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation
Tobias Weinberger, Dena Esfandyari, Denise Messerer, Gulce Percin, Christian Schleifer, Raffael Thaler, Lulu Liu, Christopher Stremmel, Vanessa Schneider, Ronald J. Vagnozzi, Jennifer Schwanenkamp, Maximilian Fischer, Katrin Busch, Kay Klapproth, Hellen Ishikawa-Ankerhold, Lukas Klösges, Anna Titova, Jeffery D. Molkentin, Yasuhiro Kobayashi, Stefan Engelhardt, Steffen Massberg, Claudia Waskow, Elisa Gomez Perdiguero, Christian Schulz
Nat Commun. 2020; 11: 4549. Published online 2020 Sep 11. doi: 10.1038/s41467-020-18287-x
PMCID:
PMC7486394
AbstractArticlePDF–4.2M
12.
The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway
Kakeru Ozaki, Takanori Yamada, Tetsuhiro Horie, Atsushi Ishizaki, Manami Hiraiwa, Takashi Iezaki, Gyujin Park, Kazuya Fukasawa, Hikari Kamada, Kazuya Tokumura, Mei Motono, Katsuyuki Kaneda, Kazuma Ogawa, Hiroki Ochi, Shingo Sato, Yasuhiro Kobayashi, Yun-Bo Shi, Peter M. Taylor, Eiichi Hinoi
Sci Signal. Author manuscript; available in PMC 2020 Jul 9.
Published in final edited form as: Sci Signal. 2019 Jul 9; 12(589): eaaw3921. Published online 2019 Jul 9. doi: 10.1126/scisignal.aaw3921
PMCID:
PMC7285885
AbstractArticlePDF–2.7M
13.
Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice
David S. Donaldson, Jolinda Pollock, Prerna Vohra, Mark P. Stevens, Neil A. Mabbott
iScience. 2020 Jun 26; 23(6): 101147. Published online 2020 May 11. doi: 10.1016/j.isci.2020.101147
PMCID:
PMC7251786
AbstractArticlePDF–6.1M
14.
RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy
Magdalena Paolino, Rubina Koglgruber, Shane J. F. Cronin, Iris Uribesalgo, Esther Rauscher, Jürgen Harreiter, Michael Schuster, Dagmar Bancher-Todesca, Blanka Pranjic, Maria Novatchkova, Juan P. Fededa, Andrea J. White, Verena Sigl, Sabine Dekan, Thomas Penz, Christoph Bock, Lukas Kenner, Georg A. Holländer, Graham Anderson, Alexandra Kautzky-Willer, Josef M. Penninger
Nature. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Nature. 2021 Jan 1; 589(7842): 442–447. Published online 2020 Dec 23. doi: 10.1038/s41586-020-03071-0
PMCID:
PMC7116618
AbstractArticlePDF–6.7M
15.
Developmental origin, functional maintenance and genetic rescue of osteoclasts
Christian E. Jacome-Galarza, Gulce I. Percin, James T. Muller, Elvira Mass, Tomi Lazarov, Jiri Eitler, Martina Rauner, Vijay K. Yadav, Lucile Crozet, Mathieu Bohm, Pierre-Louis Loyher, Gerard Karsenty, Claudia Waskow, Frederic Geissmann
Nature. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Nature. 2019 Apr; 568(7753): 541–545. Published online 2019 Apr 10. doi: 10.1038/s41586-019-1105-7
PMCID:
PMC6910203
AbstractArticlePDF–2.4M
16.
Creation of RANKL mutants with low affinity for decoy receptor OPG and their potential anti‐fibrosis activity
Yizhou Wang, Timo Michiels, Rita Setroikromo, Ronald van Merkerk, Robbert H. Cool, Wim J. Quax
FEBS J. 2019 Sep; 286(18): 3582–3593. Published online 2019 May 25. doi: 10.1111/febs.14925
PMCID:
PMC6852375
AbstractArticlePDF–3.1M
17.
Specific RANK Cytoplasmic Motifs Drive Osteoclastogenesis
Yuyu Li, Zhenqi Shi, Joel Jules, Shenyuan Chen, Robert A. Kesterson, Dongfeng Zhao, Ping Zhang, Xu Feng
J Bone Miner Res. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: J Bone Miner Res. 2019 Oct; 34(10): 1938–1951. Published online 2019 Aug 2. doi: 10.1002/jbmr.3810
PMCID:
PMC6813862
AbstractArticlePDF–2.3M
18.
Specification of Sprouty2 functions in osteogenesis in in vivo context
Barbora Vesela, Eva Svandova, Maria Hovorakova, Renata Peterkova, Adela Kratochvilova, Martina Pasovska, Alice Ramesova, Herve Lesot, Eva Matalova
Organogenesis. 2019; 15(4): 111–119. Published online 2019 Sep 4. doi: 10.1080/15476278.2019.1656995
PMCID:
PMC6804697
AbstractArticlePDF–1.9M
19.
Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice
Amélie E. Coudert, François Redelsperger, Yasmine Chabbi-Achengli, Cécile Vernochet, Caroline Marty, Xavier Decrouy, Thierry Heidmann, Marie-Christine de Vernejoul, Anne Dupressoir
Bone Rep. 2019 Dec; 11: 100214. Published online 2019 Jul 10. doi: 10.1016/j.bonr.2019.100214
PMCID:
PMC6637224
AbstractArticlePDF–1.8M
20.
Aire-expressing ILC3-like cells in the lymph node display potent APC features
Tomoyoshi Yamano, Jan Dobeš, Matouš Vobořil, Madlen Steinert, Tomáš Brabec, Natalia Ziętara, Martina Dobešová, Caspar Ohnmacht, Martti Laan, Part Peterson, Vladimir Benes, Radislav Sedláček, Rikinari Hanayama, Michal Kolář, Ludger Klein, Dominik Filipp
J Exp Med. 2019 May 6; 216(5): 1027–1037. Published online 2019 Mar 27. doi: 10.1084/jem.20181430
PMCID:
PMC6504225
AbstractArticlePDF–2.6M

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