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Select item 112524411.

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Chao Huang, Wenting Zhu, Qing Li, Yuchen Lei, Xi Chen, Shaorui Liu, Dianyu Chen, Lijian Zhong, Feng Gao, Shujie Fu, Danyang He, Jinsong Li, Heping Xu

Nat Commun. 2024; 15: 5981. Published online 2024 Jul 16. doi: 10.1038/s41467-024-50266-4

PMCID:: PMC11252441

Abstract Article PDF–3.9M

Select item 110043972.

NK cell-activating receptor NKp46 does not participate in the development of obesity-induced inflammation and insulin resistance

Gracia Nathalie, Beatriz Dal Santo Francisco Bonamichi, Jieun Kim, Jiwon Jeong, Haneul Kang, Emirrio Reinaldie Hartland, Eveline Eveline, Jongsoon Lee

Mol Cells. 2024 Mar; 47(3): 100007. Published online 2023 Dec 28. doi: 10.1016/j.mocell.2023.100007

PMCID:: PMC11004397

Abstract Article PDF–1.9M

Select item 107838033.

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

Tommaso Torcellan, Christin Friedrich, Rémi Doucet-Ladevèze, Thomas Ossner, Virgínia Visaconill Solé, Sofie Riedmann, Milas Ugur, Fabian Imdahl, Stephan P. Rosshart, Sebastian J. Arnold, Mercedes Gomez de Agüero, Nicola Gagliani, Richard A. Flavell, Simone Backes, Wolfgang Kastenmüller, Georg Gasteiger

Immunity. 2024 Jan 9; 57(1): 124–140.e7. doi: 10.1016/j.immuni.2023.11.018

PMCID:: PMC10783803

Abstract Article

Select item 107834374.

Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway

Vincent Peng, Tihana Trsan, Raki Sudan, Bishan Bhattarai, Victor S. Cortez, Martina Molgora, Jean Vacher, Marco Colonna

J Exp Med. 2024 Mar 4; 221(3): e20230124. Published online 2024 Jan 10. doi: 10.1084/jem.20230124

PMCID:: PMC10783437

Abstract Article PDF–4.0M

Select item 107557245.

Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection

Jessica Vetters, Mary van Helden, Clint De Nolf, Sofie Rennen, Eva Cloots, Evelien Van De Velde, Farzaneh Fayazpour, Justine Van Moorleghem, Manon Vanheerswynghels, Karl Vergote, Louis Boon, Eric Vivier, Bart N. Lambrecht, Sophie Janssens

iScience. 2023 Dec 15; 26(12): 108570. Published online 2023 Nov 23. doi: 10.1016/j.isci.2023.108570

PMCID:: PMC10755724

Abstract Article PDF–8.3M

Select item 103740206.

Largely preserved functionality after the combined loss of NKG2D, NCR1 and CD16 demonstrates the remarkable plasticity of NK cell responsiveness

Vanna Imširović, Maja Lenartić, Felix M. Wensveen, Bojan Polić, Vedrana Jelenčić

Front Immunol. 2023; 14: 1191884. Published online 2023 Jul 13. doi: 10.3389/fimmu.2023.1191884

PMCID:: PMC10374020

Abstract Article PDF–4.4M

Select item 101658767.

The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker, Xiyu Ma, Ying Zhang, Sourav Chowdhury, Karla F. Meza-Sosa, Mercedes Lewandrowski, Haiwei Zhang, Marjorie Rowe, Arthur McClelland, Hao Wu, Caroline Junqueira, Judy Lieberman

Nature. Author manuscript; available in PMC 2023 May 8.

Published in final edited form as: Nature. 2023 Apr; 616(7956): 348–356. Published online 2023 Apr 5. doi: 10.1038/s41586-023-05912-0

Correction in:: Nature. 2023 May 17

PMCID:: PMC10165876

Abstract Article PDF–4.9M

Select item 95601528.

The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function

Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, Wayne M Yokoyama

eLife. 2022; 11: e77294. Published online 2022 Oct 3. doi: 10.7554/eLife.77294

PMCID:: PMC9560152

Abstract Article PDF–5.3M

Select item 95514559.

NKp46⁺ natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection

Nicolas Pionnier, Julio Furlong-Silva, Stefano A. P. Colombo, Amy E. Marriott, Valerine C. Chunda, Bertrand L. Ndzeshang, Hanna Sjoberg, John Archer, Andrew Steven, Samuel Wanji, Mark J. Taylor, Joseph D. Turner

Front Immunol. 2022; 13: 969340. Published online 2022 Sep 27. doi: 10.3389/fimmu.2022.969340

PMCID:: PMC9551455

Abstract Article PDF–3.9M

Select item 913540310.

Binary outcomes of enhancer activity underlie stable random monoallelic expression

Djem U Kissiov, Alexander Ethell, Sean Chen, Natalie K Wolf, Chenyu Zhang, Susanna M Dang, Yeara Jo, Katrine N Madsen, Ishan Paranjpe, Angus Y Lee, Bryan Chim, Stefan A Muljo, David H Raulet

eLife. 2022; 11: e74204. Published online 2022 May 26. doi: 10.7554/eLife.74204

PMCID:: PMC9135403

Abstract Article PDF–3.7M

Select item 901479411.

EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model

Xixi Tao, Rui Zhang, Ronglu Du, Tingting Yu, Hui Yang, Jiwen Li, Yuhong Wang, Qian Liu, Shengkai Zuo, Xi Wang, Michael Lazarus, Lu Zhou, Bangmao Wang, Ying Yu, Yujun Shen

J Exp Med. 2022 May 2; 219(5): e20212414. Published online 2022 Apr 14. doi: 10.1084/jem.20212414

PMCID:: PMC9014794

Abstract Article PDF–8.1M

Select item 900750012.

When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer

Mohamed S. Hasim, Marie Marotel, Jonathan J. Hodgins, Elisabetta Vulpis, Olivia J. Makinson, Sara Asif, Han-Yun Shih, Amit K. Scheer, Olivia MacMillan, Felipe G. Alonso, Kelly P. Burke, David P. Cook, Rui Li, Maria Teresa Petrucci, Angela Santoni, Padraic G. Fallon, Arlene H. Sharpe, Giuseppe Sciumè, André Veillette, Alessandra Zingoni, Douglas A. Gray, Arleigh McCurdy, Michele Ardolino

Sci Adv. 2022 Apr; 8(15): eabj3286. Published online 2022 Apr 13. doi: 10.1126/sciadv.abj3286

PMCID:: PMC9007500

Abstract Article PDF–3.1M

Select item 900580913.

Natural Killer Cells Infiltration in the Joints Exacerbates Collagen-Induced Arthritis

Lisheng Wu, Ran Wang, Yi Zhou, Di Zhao, Feilong Chen, Xianghui Wu, Xiaoguang Chen, Shixian Chen, Juan Li, Junqing Zhu

Front Immunol. 2022; 13: 860761. Published online 2022 Mar 30. doi: 10.3389/fimmu.2022.860761

PMCID:: PMC9005809

Abstract Article PDF–9.9M

Select item 899268414.

Ly49E separates liver ILC1s into embryo-derived and postnatal subsets with different functions

Yawen Chen, Xianwei Wang, Xiaolei Hao, Bin Li, Wanyin Tao, Shu Zhu, Kun Qu, Haiming Wei, Rui Sun, Hui Peng, Zhigang Tian

J Exp Med. 2022 May 2; 219(5): e20211805. Published online 2022 Mar 29. doi: 10.1084/jem.20211805

PMCID:: PMC8992684

Abstract Article PDF–6.9M

Select item 892634015.

Extracellular matrix proteins regulate NK cell function in peripheral tissues

Mark D. Bunting, Maulik Vyas, Marta Requesens, Adam Langenbucher, Erik B. Schiferle, Robert T. Manguso, Michael S. Lawrence, Shadmehr Demehri

Sci Adv. 2022 Mar; 8(11): eabk3327. Published online 2022 Mar 16. doi: 10.1126/sciadv.abk3327

PMCID:: PMC8926340

Abstract Article PDF–4.1M

Select item 888583716.

Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment

Ying Jin, Xiaoyu An, Binchen Mao, Ruilin Sun, Rajendra Kumari, Xiaobo Chen, Yongli Shan, Mingfa Zang, Ling Xu, Jan Muntel, Kristina Beeler, Roland Bruderer, Lukas Reiter, Sheng Guo, Demin Zhou, Qi-Xiang Li, Xuesong Ouyang

Sci Rep. 2022; 12: 3278. Published online 2022 Feb 28. doi: 10.1038/s41598-022-07153-z

PMCID:: PMC8885837

Abstract Article PDF–2.9M

Select item 884928617.

Functional visualization of NK cell-mediated killing of metastatic single tumor cells

Hiroshi Ichise, Shoko Tsukamoto, Tsuyoshi Hirashima, Yoshinobu Konishi, Choji Oki, Shinya Tsukiji, Satoshi Iwano, Atsushi Miyawaki, Kenta Sumiyama, Kenta Terai, Michiyuki Matsuda

eLife. 2022; 11: e76269. Published online 2022 Feb 3. doi: 10.7554/eLife.76269

PMCID:: PMC8849286

Abstract Article PDF–4.4M

Select item 876388618.

The transcription factor HIF-1α mediates plasticity of NKp46⁺ innate lymphoid cells in the gut

Ewelina Krzywinska, Michal Sobecki, Shunmugam Nagarajan, Julian Zacharjasz, Murtaza M. Tambuwala, Abigaelle Pelletier, Eoin Cummins, Dagmar Gotthardt, Joachim Fandrey, Yann M. Kerdiles, Carole Peyssonnaux, Cormac T. Taylor, Veronika Sexl, Christian Stockmann

J Exp Med. 2022 Feb 7; 219(2): e20210909. Published online 2022 Jan 13. doi: 10.1084/jem.20210909

PMCID:: PMC8763886

Abstract Article PDF–8.9M

Select item 871867919.

Chronic IL-15 Stimulation and Impaired mTOR Signaling and Metabolism in Natural Killer Cells During Acute Myeloid Leukemia

Berna Bou-Tayeh, Vladimir Laletin, Nassim Salem, Sylvaine Just-Landi, Joanna Fares, Raphael Leblanc, Marielle Balzano, Yann M. Kerdiles, Ghislain Bidaut, Olivier Hérault, Daniel Olive, Michel Aurrand-Lions, Thierry Walzer, Jacques A. Nunès, Cyril Fauriat

Front Immunol. 2021; 12: 730970. Published online 2021 Dec 17. doi: 10.3389/fimmu.2021.730970