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Select item 116105221.

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds

Janani Ramachandran, Wanlu Chen, Rachel K. Lex, Kathryn E. Windsor, Hyunji Lee, Tingchang Wang, Weiqiang Zhou, Hongkai Ji, Steven A. Vokes

Dev Biol. Author manuscript; available in PMC 2024 Dec 2.

Published in final edited form as: Dev Biol. 2023 Dec; 504: 128–136. Published online 2023 Oct 5. doi: 10.1016/j.ydbio.2023.10.001

PMCID:: PMC11610522

Abstract Article PDF–1.7M

Select item 111370272.

Acute depletion of BRG1 reveals its primary function as an activator of transcription

Gang Ren, Wai Lim Ku, Guangzhe Ge, Jackson A. Hoffman, Jee Youn Kang, Qingsong Tang, Kairong Cui, Yong He, Yukun Guan, Bin Gao, Chengyu Liu, Trevor K. Archer, Keji Zhao

Nat Commun. 2024; 15: 4561. Published online 2024 May 29. doi: 10.1038/s41467-024-48911-z

PMCID:: PMC11137027

Abstract Article PDF–4.1M

Select item 110404993.

BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination

Jiajia Wang, Lijun Yang, Yiwen Du, Jincheng Wang, Qinjie Weng, Xuezhao Liu, Eva Nicholson, Mei Xin, Qing Richard Lu

J Cell Biol. 2024 Jul 1; 223(7): e202310143. Published online 2024 Apr 23. doi: 10.1083/jcb.202310143

PMCID:: PMC11040499

Abstract Article PDF–5.3M

Select item 110074754.

SMARCA4 Loss and Mutated β-Catenin Induce Proliferative Lesions in the Murine Embryonic Cerebellum

Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Michael Spohn, Ulrich Schüller

J Neurosci. 2024 Apr 10; 44(15): e1605232024. Prepublished online 2024 Feb 21. doi: 10.1523/JNEUROSCI.1605-23.2024

PMCID:: PMC11007475

Abstract Article PDF–26M

Select item 109040575.

Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus

Qiliang Xin, Iris Feng, Guoyun Yu, Jurrien Dean

J Clin Invest. 2024 Mar 1; 134(5): e174194. Published online 2024 Mar 1. doi: 10.1172/JCI174194

PMCID:: PMC10904057

Abstract Article PDF–18M

Select item 108350436.

Dancr-BRG1 regulates Nfatc1 transcription and Pgc1β-dependent metabolic shifts in osteoclastogenesis

Zheng Zhang, Yichen Meng, Tao Lin, Zhanrong Zhang, Zhengbo Tao, Haozan Yin, Fu Yang, Xuhui Zhou

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2313656121. Published online 2024 Jan 22. doi: 10.1073/pnas.2313656121

PMCID:: PMC10835043

Abstract Article PDF–13M

Select item 107569327.

SMARCA4 mutation causes human otosclerosis and a similar phenotype in mice

Max Drabkin, Matan M. Jean, Yael Noy, Daniel Halperin, Yuval Yogev, Ohad Wormser, Regina Proskorovsky-Ohayon, Vadim Dolgin, Noam Levaot, Vlad Brumfeld, Shira Ovadia, Mor Kishner, Udi Kazenell, Karen B. Avraham, Ilan Shelef, Ohad S. Birk

J Med Genet. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: J Med Genet. 2024 Jan 19; 61(2): 117–124. Published online 2024 Jan 19. doi: 10.1136/jmg-2023-109264

PMCID:: PMC10756932

Abstract Article PDF–923K

Select item 106886838.

Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice

Baocai Wang, Benedikt Kaufmann, Carolin Mogler, Suyang Zhong, Yuhan Yin, Zhangjun Cheng, Roland M. Schmid, Helmut Friess, Norbert Hüser, Guido von Figura, Daniel Hartmann

PLoS One. 2023; 18(11): e0294257. Published online 2023 Nov 30. doi: 10.1371/journal.pone.0294257

PMCID:: PMC10688683

Abstract Article PDF–1.5M

Select item 106213159.

MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

Carolin Göbel, Shweta Godbole, Melanie Schoof, Dörthe Holdhof, Catena Kresbach, Carolin Loose, Julia Neumann, Ulrich Schüller

Acta Neuropathol Commun. 2023; 11: 174. Published online 2023 Nov 2. doi: 10.1186/s40478-023-01654-2

PMCID:: PMC10621315

Abstract Article PDF–5.1M

Select item 1051026710.

Shuting Li, Congwei Luo, Sijia Chen, Yiyi Zhuang, Yue Ji, Yiqun Zeng, Yao Zeng, Xiaoyang He, Jing Xiao, Huizhen Wang, Xiaowen Chen, Haibo Long, Fenfen Peng

J Transl Med. 2023; 21: 639. Published online 2023 Sep 19. doi: 10.1186/s12967-023-04469-w

PMCID:: PMC10510267

Abstract Article PDF–3.0M

Select item 1050641311.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 1048200712.

SWI/SNF complexes are required for retinal pigmented epithelium differentiation and for the inhibition of cell proliferation and neural differentiation programs

Shai Ovadia, Guizhong Cui, Ran Elkon, Mazal Cohen-Gulkar, Nitay Zuk-Bar, Tran Tuoc, Naihe Jing, Ruth Ashery-Padan

Development. 2023 Aug 15; 150(16): dev201488. Published online 2023 Aug 21. doi: 10.1242/dev.201488

PMCID:: PMC10482007

Abstract Article

Select item 1040428613.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 1030785214.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 1028414015.

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1

Wei Shi, Angel P. Scialdone, James I. Emerson, Liu Mei, Lauren K. Wasson, Haley A. Davies, Christine E. Seidman, Jonathan G. Seidman, Jeanette G. Cook, Frank L. Conlon

Circ Res. 2023 Jun 23; 133(1): 48–67. Published online 2023 May 31. doi: 10.1161/CIRCRESAHA.122.322223

PMCID:: PMC10284140

Abstract Article PDF–26M

Select item 1015436116.

Generation of new transgenic SMARCA4‐deficient mouse models results in neuromuscular weakness and paralysis of limbs

Sina Neyazi, Lea Altendorf, Dora Schwetje, Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Ulrich Schüller

Brain Pathol. 2023 May; 33(3): e13146. Published online 2022 Dec 29. doi: 10.1111/bpa.13146

PMCID:: PMC10154361

Article PDF–346K

Select item 1002740217.

Divergent transcriptional regulation of astrocyte reactivity across disorders

Joshua E. Burda, Timothy M. O’Shea, Yan Ao, Keshav B. Suresh, Shinong Wang, Alexander M. Bernstein, Ashu Chandra, Sandeep Deverasetty, Riki Kawaguchi, Jae H. Kim, Sarah McCallum, Alexandra Rogers, Shalaka Wahane, Michael V. Sofroniew

Nature. Author manuscript; available in PMC 2023 Mar 20.

Published in final edited form as: Nature. 2022 Jun; 606(7914): 557–564. Published online 2022 May 25. doi: 10.1038/s41586-022-04739-5

Correction in:: Nature. 2023 Mar 28

PMCID:: PMC10027402

Abstract Article PDF–5.9M

Select item 993040018.

SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility

Atefeh Abedini, David A Landry, Angus D Macaulay, Het Vaishnav, Ashna Parbhakar, Dalia Ibrahim, Reza Salehi, Vincent Maranda, Elizabeth Macdonald, Barbara C Vanderhyden

Biol Reprod. 2023 Feb; 108(2): 279–291. Published online 2022 Nov 28. doi: 10.1093/biolre/ioac209

Correction in:: Biol Reprod. 2023 Apr; 108(4): 708.

PMCID:: PMC9930400

Abstract Article PDF–1.9M

Select item 991168719.

Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway

Xue-jun Wang, Dan Zhang, Yan-ting Yang, Xiao-ying Li, Hong-na Li, Xiao-peng Zhang, Jun-yi Long, Yun-qiong Lu, Li Liu, Guang Yang, Jie Liu, Jue Hong, Huan-gan Wu, Xiao-peng Ma

Front Immunol. 2023; 14: 1089809. Published online 2023 Jan 27. doi: 10.3389/fimmu.2023.1089809