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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
Andrew M. Kidger, Mark K. Saville, Linda K. Rushworth, Jane Davidson, Julia Stellzig, Motoharu Ono, Ludwig A. Kuebelsbeck, Klaus-Peter Janssen, Bernhard Holzmann, Jennifer P. Morton, Owen J. Sansom, Christopher J. Caunt, Stephen M. Keyse
Oncogene. 2022; 41(20): 2811–2823. Published online 2022 Apr 13. doi: 10.1038/s41388-022-02302-0
PMCID:
PMC9106580
AbstractArticlePDF–6.0M
3.
DUSP5 promotes osteogenic differentiation through SCP1/2‐dependent phosphorylation of SMAD1
Xuejiao Liu, Xuenan Liu, Yangge Du, Menglong Hu, Yueming Tian, Zheng Li, Longwei Lv, Xiao Zhang, Yunsong Liu, Yongsheng Zhou, Ping Zhang
Stem Cells. 2021 Oct; 39(10): 1395–1409. Published online 2021 Jul 10. doi: 10.1002/stem.3428
PMCID:
PMC8518947
AbstractArticlePDF–3.8M
4.
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
Bradley S. Ferguson, Sara A. Wennersten, Kimberly M. Demos-Davies, Marcello Rubino, Emma L. Robinson, Maria A. Cavasin, Matthew S. Stratton, Andrew M. Kidger, Tianjing Hu, Stephen M. Keyse, Robert A. McKnight, Robert H. Lane, Eva S. Nozik, Mary C. M. Weiser-Evans, Timothy A. McKinsey
Am J Physiol Heart Circ Physiol. 2021 Aug 1; 321(2): H382–H389. Published online 2021 Jun 18. doi: 10.1152/ajpheart.00115.2021
PMCID:
PMC8410116
AbstractArticle
5.
DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling
Nikolay Bogush, Lin Tan, Hussain Naib, Ebrahim Faizullabhoy, John W. Calvert, Siiri E. Iismaa, Ankan Gupta, Ramani Ramchandran, David I. K. Martin, Robert M. Graham, Ahsan Husain, Nawazish Naqvi
Sci Rep. 2020; 10: 21918. Published online 2020 Dec 14. doi: 10.1038/s41598-020-78825-x
PMCID:
PMC7736286
AbstractArticlePDF–7.0M
6.
Dual specificity phosphatase 5 regulates perfusion recovery in experimental peripheral artery disease
Satyanarayana Alleboina, Dawit Ayalew, Rahul Peravali, Lingdan Chen, Thomas Wong, Ayotunde O Dokun
Vasc Med. Author manuscript; available in PMC 2020 Nov 13.
Published in final edited form as: Vasc Med. 2019 Oct; 24(5): 395–404. Published online 2019 Aug 26. doi: 10.1177/1358863X19866254
PMCID:
PMC7664318
AbstractArticlePDF–1.7M
7.
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
Adelaida M Celaya, Isabel Sánchez-Pérez, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Laura Pintado-Berninches, Rosario Perona, Silvia Murillo-Cuesta, Isabel Varela-Nieto
eLife. 2019; 8: e39159. Published online 2019 Apr 2. doi: 10.7554/eLife.39159
PMCID:
PMC6464786
AbstractArticlePDF–5.9M
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
DUSP5 functions as a feedback regulator of TNFα-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes
Justine S. Habibian, Mitra Jefic, Rushita A. Bagchi, Robert H. Lane, Robert A. McKnight, Timothy A. McKinsey, Ron F. Morrison, Bradley S. Ferguson
Sci Rep. 2017; 7: 12879. Published online 2017 Oct 10. doi: 10.1038/s41598-017-12861-y
PMCID:
PMC5635013
AbstractArticlePDF–2.4M
10.
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling
Andrew M. Kidger, Linda K. Rushworth, Julia Stellzig, Jane Davidson, Christopher J. Bryant, Cassidy Bayley, Edward Caddye, Tim Rogers, Stephen M. Keyse, Christopher J. Caunt
Proc Natl Acad Sci U S A. 2017 Jan 17; 114(3): E317–E326. Published online 2017 Jan 4. doi: 10.1073/pnas.1614684114
Correction in:
Proc Natl Acad Sci U S A. 2017 Sep 5; 114(36): E7651.
PMCID:
PMC5255582
AbstractArticlePDF–2.1M
11.
Dual Specificity Phosphatase 5 Is Essential for T Cell Survival
Raman G. Kutty, Gang Xin, David M. Schauder, Stephanie M. Cossette, Michelle Bordas, Weiguo Cui, Ramani Ramchandran
PLoS One. 2016; 11(12): e0167246. Published online 2016 Dec 9. doi: 10.1371/journal.pone.0167246
PMCID:
PMC5147890
AbstractArticlePDF–2.2M
12.
Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription Factor
Camille Buffet, Maria-Grazia Catelli, Karine Hecale-Perlemoine, Léopoldine Bricaire, Camille Garcia, Anne Gallet-Dierick, Stéphanie Rodriguez, Françoise Cormier, Lionel Groussin
PLoS One. 2015; 10(12): e0145484. Published online 2015 Dec 21. doi: 10.1371/journal.pone.0145484
PMCID:
PMC4687125
AbstractArticlePDF–1.9M
13.
Dusp5 negatively regulates IL-33-mediated eosinophil survival and function
Derek A Holmes, Jung-Hua Yeh, Donghong Yan, Min Xu, Andrew C Chan
EMBO J. 2015 Jan 13; 34(2): 218–235. Published online 2014 Nov 14. doi: 10.15252/embj.201489456
PMCID:
PMC4337062
AbstractArticlePDF–1.1M
14.
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression
Linda K. Rushworth, Andrew M. Kidger, Laurent Delavaine, Graeme Stewart, Susanne van Schelven, Jane Davidson, Christopher J. Bryant, Edward Caddye, Philip East, Christopher J. Caunt, Stephen M. Keyse
Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51): 18267–18272. Published online 2014 Dec 8. doi: 10.1073/pnas.1420159112
PMCID:
PMC4280588
AbstractArticlePDF–1.3M
15.
Differential Phosphorylation of Smad1 Integrates BMP and Neurotrophin Pathways through Erk/Dusp in Axon Development
Mattéa J. Finelli, Kevin J. Murphy, Lei Chen, Hongyan Zou
Cell Rep. Author manuscript; available in PMC 2013 Jun 10.
Published in final edited form as: Cell Rep. 2013 May 30; 3(5): 1592–1606. Published online 2013 May 9. doi: 10.1016/j.celrep.2013.04.011
PMCID:
PMC3677165
AbstractArticlePDF–5.9M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
T-cell Development and Function Are Modulated by Dual Specificity Phosphatase DUSP5
Panu E. Kovanen, Jérôme Bernard, Amin Al-Shami, Chengyu Liu, Julie Bollenbacher-Reilley, Lynn Young, Cynthia Pise-Masison, Rosanne Spolski, Warren J. Leonard
J Biol Chem. 2008 Jun 20; 283(25): 17362–17369. doi: 10.1074/jbc.M709887200
PMCID:
PMC2427334
AbstractArticlePDF–564K
20.
Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells
Wolfgang Breitwieser, Steve Lyons, Ann Marie Flenniken, Garry Ashton, Gail Bruder, Mark Willington, Georges Lacaud, Valerie Kouskoff, Nic Jones
Genes Dev. 2007 Aug 15; 21(16): 2069–2082. doi: 10.1101/gad.430207
PMCID:
PMC1948861
AbstractArticlePDF–1.2M

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