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Items: 1 to 20 of 298

1.
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development
Timothy J. Mead, Sumit Bhutada, Simon J. Foulcer, Niccolò Peruzzi, Courtney M. Nelson, Deborah E. Seifert, Jonathan Larkin, Karin Tran-Lundmark, Jorge Filmus, Suneel S. Apte
Matrix Biol. Author manuscript; available in PMC 2024 Oct 31.
Published in final edited form as: Matrix Biol. 2024 Aug; 131: 1–16. Published online 2024 May 13. doi: 10.1016/j.matbio.2024.05.003
PMCID:
PMC11526477
AbstractArticlePDF–5.2M
2.
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton
Asra Almubarak, Qiuwan Zhang, Cheng-Hai Zhang, Noor Abdelwahab, Tsutomu Kume, Andrew B. Lassar, Fred B. Berry
Development. 2024 Aug 15; 151(16): dev202798. Published online 2024 Aug 22. doi: 10.1242/dev.202798
PMCID:
PMC11361642
AbstractArticle
3.
LncRNAs in the Dlk1-Dio3 Domain Are Essential for Mid-Embryonic Heart Development
Xiangqi Teng, Hongjuan He, Haoran Yu, Ximeijia Zhang, Jie Xing, Jiwei Shen, Chenghao Li, Mengyun Wang, Lan Shao, Ziwen Wang, Haopeng Yang, Yan Zhang, Qiong Wu
Int J Mol Sci. 2024 Aug; 25(15): 8184. Published online 2024 Jul 26. doi: 10.3390/ijms25158184
PMCID:
PMC11311489
AbstractArticlePDF–3.1M
4.
Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis
Archana Kumari, Nicole E. Franks, Libo Li, Gabrielle Audu, Sarah Liskowicz, John D. Johnson, Charlotte M. Mistretta, Benjamin L. Allen
PLoS One. 2024; 19(6): e0294835. Published online 2024 Jun 7. doi: 10.1371/journal.pone.0294835
PMCID:
PMC11161123
AbstractArticlePDF–7.0M
5.
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis
Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina
J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787
PMCID:
PMC11014657
AbstractArticlePDF–16M
6.
Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis
Boang Han, Yu Wang, Shen Yue, Yun-hao Zhang, Lun Kuang, Bin-bin Gao, Yue Wang, Ziyu Zhang, Xiaohong Pu, Xin-fa Wang, Chi-chung Hui, Ting-ting Yu, Chen Liu, Steven Y. Cheng
JCI Insight. 2024 Mar 22; 9(6): e176044. Published online 2024 Feb 15. doi: 10.1172/jci.insight.176044
PMCID:
PMC10972619
AbstractArticlePDF–3.1M
7.
Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
Jessica E. Pritchard, Juliette E. Pearce, Inge A.M. Snoeren, Stijn N.R. Fuchs, Katrin Götz, Fabian Peisker, Silke Wagner, Adam Benabid, Niklas Lutterbach, Vanessa Klöker, James S. Nagai, Monica T. Hannani, Anna K. Galyga, Ellen Sistemich, Bella Banjanin, Niclas Flosdorf, Eric Bindels, Kathrin Olschok, Katharina Biaesch, Nicolas Chatain, Neha Bhagwat, Andrew Dunbar, Rita Sarkis, Olaia Naveiras, Marie-Luise Berres, Steffen Koschmieder, Ross L. Levine, Ivan G. Costa, Hélène F.E. Gleitz, Rafael Kramann, Rebekka K. Schneider
Cell Rep. 2024 Jan 23; 43(1): 113608. Published online 2023 Dec 20. doi: 10.1016/j.celrep.2023.113608
PMCID:
PMC10828549
AbstractArticle
8.
Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay
PLoS Genet. 2023 Nov; 19(11): e1011028. Published online 2023 Nov 9. doi: 10.1371/journal.pgen.1011028
PMCID:
PMC10662714
AbstractArticlePDF–5.4M
9.
20-αHydroxycholesterol, an oxysterol in human breast milk, reverses mouse neonatal white matter injury through Gli-dependent oligodendrogenesis
Agnes S. Chao, Pavle Matak, Kelly Pegram, James Powers, Collin Hutson, Rebecca Jo, Laura Dubois, J. Will Thompson, P. Brian Smith, Vaibhav Jain, Chunlei Liu, Noelle E. Younge, Blaire Rikard, Estefany Y. Reyes, Mari L. Shinohara, Simon G. Gregory, Ronald N. Goldberg, Eric J. Benner
Cell Stem Cell. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: Cell Stem Cell. 2023 Aug 3; 30(8): 1054–1071.e8. doi: 10.1016/j.stem.2023.07.010
PMCID:
PMC10625465
AbstractArticlePDF–3.2M
10.
Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development
Jiyoung Lee, Yeonjoo Kim, Paris Ataliotis, Hyung-Goo Kim, Dae-Won Kim, Dorothy C. Bennett, Nigel A. Brown, Lawrence C. Layman, Soo-Hyun Kim
Sci Rep. 2023; 13: 12309. Published online 2023 Jul 29. doi: 10.1038/s41598-023-38017-9
PMCID:
PMC10387110
AbstractArticlePDF–11M
11.
Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos
Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng
Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245
PMCID:
PMC10203710
AbstractArticlePDF–4.6M
12.
Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse
Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L. Galea, Nicholas D. E. Greene, Andrew J. Copp
Dis Model Mech. 2023 Mar 1; 16(3): dmm049858. Published online 2023 Mar 14. doi: 10.1242/dmm.049858
PMCID:
PMC10073009
AbstractArticle
13.
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
Xiaodong Li, Patrick J Gordon, John A Gaynes, Alexandra W Fuller, Randy Ringuette, Clayton P Santiago, Valerie Wallace, Seth Blackshaw, Pulin Li, Edward M Levine
eLife. 2022; 11: e78342. Published online 2022 Dec 2. doi: 10.7554/eLife.78342
PMCID:
PMC9718532
AbstractArticlePDF–14M
14.
Cbln1 regulates axon growth and guidance in multiple neural regions
Peng Han, Yuanchu She, Zhuoxuan Yang, Mengru Zhuang, Qingjun Wang, Xiaopeng Luo, Chaoqun Yin, Junda Zhu, Samie R. Jaffrey, Sheng-Jian Ji
PLoS Biol. 2022 Nov; 20(11): e3001853. Published online 2022 Nov 17. doi: 10.1371/journal.pbio.3001853
PMCID:
PMC9671368
AbstractArticlePDF–6.3M
15.
Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation
Tianli Qin, Chin Chung Ho, Boshi Wang, Chi-Chung Hui, Mai Har Sham
Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2206571119. Published online 2022 Oct 17. doi: 10.1073/pnas.2206571119
PMCID:
PMC9618052
AbstractArticlePDF–1.9M
16.
Hedgehog (HH) pathway endogenous antagonist HHIP: unique lingual expression in filiform papillae during homeostasis and ectopic in fungiform papillae during HH signaling inhibition
Archana Kumari, Libo Li, Alexandre N. Ermilov, Nicole E. Franks, Andrzej A. Dlugosz, Benjamin L. Allen, Charlotte M. Mistretta
Dev Dyn. Author manuscript; available in PMC 2023 Jul 1.
Published in final edited form as: Dev Dyn. 2022 Jul; 251(7): 1175–1195. Published online 2022 Feb 18. doi: 10.1002/dvdy.456
PMCID:
PMC9250591
AbstractArticlePDF–2.7M
17.
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway
Guangying Yang, Shan Lu, Jia Jiang, Jun Weng, Xiaomei Zeng
Int J Mol Sci. 2022 Jun; 23(11): 6014. Published online 2022 May 27. doi: 10.3390/ijms23116014
PMCID:
PMC9181541
AbstractArticlePDF–4.4M
18.
Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia
Linda Su-Feher, Anna N. Rubin, Shanni N. Silberberg, Rinaldo Catta-Preta, Kenneth J. Lim, Athena R. Ypsilanti, Iva Zdilar, Christopher S. McGinnis, Gabriel L. McKinsey, Thomas E. Rubino, Jr., Michael J. Hawrylycz, Carol Thompson, Zev J. Gartner, Luis Puelles, Hongkui Zeng, John L. R. Rubenstein, Alex S. Nord
Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2108760119. Published online 2022 Apr 4. doi: 10.1073/pnas.2108760119
PMCID:
PMC9169651
AbstractArticlePDF–3.9M
19.
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay
Dev Cell. Author manuscript; available in PMC 2022 Apr 27.
Published in final edited form as: Dev Cell. 2020 Sep 28; 54(6): 710–726.e8. Published online 2020 Jul 22. doi: 10.1016/j.devcel.2020.06.034
PMCID:
PMC9042708
AbstractArticlePDF–3.9M
20.
An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea
Wenguang Yin, Andreas Liontos, Janine Koepke, Maroua Ghoul, Luciana Mazzocchi, Xinyuan Liu, Chunyan Lu, Haoyu Wu, Athanasios Fysikopoulos, Alexandros Sountoulidis, Werner Seeger, Clemens Ruppert, Andreas Günther, Didier Y. R. Stainier, Christos Samakovlis
Development. 2022 Feb 1; 149(3): dev199804. Published online 2022 Feb 7. doi: 10.1242/dev.199804
PMCID:
PMC8918789
AbstractArticle

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