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Select item 114156001.

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun

Life Sci Alliance. 2024 Dec; 7(12): e202402719. Published online 2024 Sep 20. doi: 10.26508/lsa.202402719

PMCID:: PMC11415600

Abstract Article PDF–5.1M

Select item 113736212.

Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system

Yueheng Wu, Shaoxian Chen, Guiping Huang, Lu Zhang, Liying Zhong, Yi Feng, Pengju Wen, Juli Liu

Theranostics. 2024; 14(12): 4894–4915. Published online 2024 Aug 12. doi: 10.7150/thno.92060

PMCID:: PMC11373621

Abstract Article PDF–12M

Select item 111788423.

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics

Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri

Sci Rep. 2024; 14: 13727. Published online 2024 Jun 14. doi: 10.1038/s41598-024-64608-1

PMCID:: PMC11178842

Abstract Article PDF–5.4M

Select item 111785304.

Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models

Yang Li, Ke Ma, Zhujun Dong, Shijuan Gao, Jing Zhang, Shan Huang, Jie Yang, Guangming Fang, Yujie Li, Xiaowei Li, Carrie Welch, Emily L. Griffin, Prema Ramaswamy, Zaheer Valivullah, Xiuying Liu, Jianzeng Dong, Dao Wen Wang, Du, Wendy K. Chung, Yulin Li

J Clin Invest. 2024 Jun 17; 134(12): e177172. Published online 2024 Jun 17. doi: 10.1172/JCI177172

PMCID:: PMC11178530

Abstract Article PDF–15M

Select item 109535655.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 108911546.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 107882697.

Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development

Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang

iScience. 2024 Jan 19; 27(1): 108722. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108722

PMCID:: PMC10788269

Abstract Article PDF–11M

Select item 104787538.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 103872379.

DELE1 is protective for mitochondrial cardiomyopathy

Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.

Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003

PMCID:: PMC10387237

Abstract Article PDF–661K

Select item 1000137210.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich

Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721

PMCID:: PMC10001372

Abstract Article PDF–2.7M

Select item 956419211.

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes

Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jennifer L. Estall, Jorge L. Ruas, Pasi Tavi

Cells. 2022 Oct; 11(19): 2944. Published online 2022 Sep 20. doi: 10.3390/cells11192944

PMCID:: PMC9564192

Abstract Article PDF–3.2M

Select item 955395112.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6

PMCID:: PMC9553951

Abstract Article PDF–3.8M

Select item 930288713.

Cardiac natriuretic peptide deficiency sensitizes the heart to stress-induced ventricular arrhythmias via impaired CREB signalling

Eric J Hall, Soumojit Pal, Michael S Glennon, Puneeth Shridhar, Sidney L Satterfield, Beth Weber, Qinkun Zhang, Guy Salama, Hind Lal, Jason R Becker

Cardiovasc Res. 2022 Jun; 118(9): 2124–2138. Published online 2021 Jul 30. doi: 10.1093/cvr/cvab257

PMCID:: PMC9302887

Abstract Article PDF–1.3M

Select item 930148714.

Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli

Zheng Cao, Chengcheng Huang, Fumin Lu, Xuequan Jiang, Yong Hu, Cheng Cao, Zijing Liu

Front Mol Neurosci. 2022; 15: 901466. Published online 2022 Jul 6. doi: 10.3389/fnmol.2022.901466

PMCID:: PMC9301487

Abstract Article PDF–5.7M

Select item 917081815.

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

Elizabeth R. Greco, Anish Engineer, Tana Saiyin, Xiangru Lu, MengQi Zhang, Douglas L. Jones, Qingping Feng

J Cell Mol Med. 2022 Jun; 26(11): 3223–3234. Published online 2022 May 6. doi: 10.1111/jcmm.17328

PMCID:: PMC9170818

Abstract Article PDF–4.0M

Select item 878927916.

BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk

Qing-Tao Meng, Xian-Yu Liu, Xue-Ting Liu, Juan Liu, Admire Munanairi, Devin M Barry, Benlong Liu, Hua Jin, Yu Sun, Qianyi Yang, Fang Gao, Li Wan, Jiahang Peng, Jin-Hua Jin, Kai-Feng Shen, Ray Kim, Jun Yin, Ailin Tao, Zhou-Feng Chen

eLife. 2021; 10: e71689. Published online 2021 Dec 17. doi: 10.7554/eLife.71689

PMCID:: PMC8789279

Abstract Article PDF–9.3M

Select item 874209917.

Decrease of Pdzrn3 is required for heart maturation and protects against heart failure

Mathieu Pernot, Béatrice Jaspard-vinassa, Alice Abelanet, Sebastien Rubin, Isabelle Forfar, Sylvie Jeanningros, Laura Cetran, Murielle Han-Yee Yu, Elise Balse, Stéphane Hatem, Pascale Dufourcq, Thierry Couffinhal, Cécile Duplàa

Sci Rep. 2022; 12: 8. Published online 2022 Jan 7. doi: 10.1038/s41598-021-03795-7

PMCID:: PMC8742099

Abstract Article PDF–3.8M

Select item 872088118.

The Role of Sorting Nexin 17 in Cardiac Development

Yufei Wu, Yaqun Zhou, Jian Huang, Ke Ma, Tianyou Yuan, Yong Jiang, Maoqing Ye, Jun Li

Front Cardiovasc Med. 2021; 8: 748891. Published online 2021 Dec 20. doi: 10.3389/fcvm.2021.748891

PMCID:: PMC8720881

Abstract Article PDF–9.3M

Select item 848249919.

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

Xiaoli Zhang, Ze Wang, Qing Xu, Yuhan Chen, Wen Liu, Tong Zhong, Hongchang Li, Chengshi Quan, Lingqiang Zhang, Chun-Ping Cui

iScience. 2021 Oct 22; 24(10): 103097. Published online 2021 Sep 10. doi: 10.1016/j.isci.2021.103097

PMCID:: PMC8482499

Abstract Article PDF–5.1M

Select item 840990020.

The SRSF4–GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy

Javier Larrasa-Alonso, María Villalba-Orero, Carlos Martí-Gómez, Paula Ortiz-Sánchez, Marina M. López-Olañeta, M. Ascensión Rey-Martín, Fátima Sánchez-Cabo, François McNicoll, Michaela Müller-McNicoll, Pablo García-Pavía, Enrique Lara-Pezzi

Circ Res. 2021 Sep 3; 129(6): 669–683. Published online 2021 Aug 2. doi: 10.1161/CIRCRESAHA.120.318577