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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 83531672.

STAU2 binds a complex RNA cargo that changes temporally with production of diverse intermediate progenitor cells during mouse corticogenesis

Rebecca Chowdhury, Yue Wang, Melissa Campbell, Susan K. Goderie, Francis Doyle, Scott A. Tenenbaum, Gretchen Kusek, Thomas R. Kiehl, Suraiya A. Ansari, Nathan C. Boles, Sally Temple

Development. 2021 Aug 1; 148(15): dev199376. Published online 2021 Aug 3. doi: 10.1242/dev.199376

PMCID:: PMC8353167

Abstract Article

Select item 83132393.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82666174.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 81864485.

An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia

Jeevisha Bajaj, Michael Hamilton, Yutaka Shima, Kendall Chambers, Kyle Spinler, Eric L. Van Nostrand, Brian A. Yee, Steven M. Blue, Michael Chen, David Rizzeri, Charles Chuah, Vivian G. Oehler, H. Elizabeth Broome, Roman Sasik, James Scott-Browne, Anjana Rao, Gene W. Yeo, Tannishtha Reya

Nat Cancer. Author manuscript; available in PMC 2021 Jun 8.

Published in final edited form as: Nat Cancer. 2020 Apr; 1(4): 410–422. Published online 2020 Apr 20. doi: 10.1038/s43018-020-0054-2

PMCID:: PMC8186448

Abstract Article PDF–2.5M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78176957.

Accelerating functional gene discovery in osteoarthritis

Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J. Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Antonio C. Bianco, Alan Boyde, Eleftheria Zeggini, Peter I. Croucher, Graham R. Williams, J. H. Duncan Bassett

Nat Commun. 2021; 12: 467. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20761-5

Correction in:: Nat Commun. 2021; 12: 3302.

PMCID:: PMC7817695

Abstract Article PDF–8.0M

Select item 66927708.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 66023009.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 660091310.

β-Actin mRNA interactome mapping by proximity biotinylation

Joyita Mukherjee, Orit Hermesh, Carolina Eliscovich, Nicolas Nalpas, Mirita Franz-Wachtel, Boris Maček, Ralf-Peter Jansen

Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12863–12872. Published online 2019 Jun 12. doi: 10.1073/pnas.1820737116

PMCID:: PMC6600913

Abstract Article PDF–2.4M

Select item 648095511.

Altered Glutamate Receptor Ionotropic Delta Subunit 2 Expression in Stau2-Deficient Cerebellar Purkinje Cells in the Adult Brain

Helena F. Pernice, Rico Schieweck, Mehrnoosh Jafari, Tobias Straub, Martin Bilban, Michael A. Kiebler, Bastian Popper

Int J Mol Sci. 2019 Apr; 20(7): 1797. Published online 2019 Apr 11. doi: 10.3390/ijms20071797

PMCID:: PMC6480955

Abstract Article PDF–3.1M

Select item 647767612.

Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

Simone Heber, Imre Gáspár, Jan-Niklas Tants, Johannes Günther, Sandra M. Fernandez Moya, Robert Janowski, Anne Ephrussi, Michael Sattler, Dierk Niessing

Nat Commun. 2019; 10: 1659. Published online 2019 Apr 10. doi: 10.1038/s41467-019-09655-3

PMCID:: PMC6477676

Abstract Article PDF–4.3M

Select item 645951013.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 505358214.

RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes

Yan Cao, Juan Du, Dandan Chen, Qian Wang, Nana Zhang, Xiaoyun Liu, Xiaoyu Liu, Jing Weng, Yuanjing Liang, Wei Ma

Cell Cycle. 2016; 15(19): 2608–2618. Published online 2016 Jul 19. doi: 10.1080/15384101.2016.1208869

PMCID:: PMC5053582

Abstract Article PDF–1.0M

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 346633516.

Asymmetric Segregation of the Double-Stranded RNA Binding Protein Staufen2 during Mammalian Neural Stem Cell Divisions Promotes Lineage Progression

Gretchen Kusek, Melissa Campbell, Frank Doyle, Scott A. Tenenbaum, Michael Kiebler, Sally Temple

Cell Stem Cell. Author manuscript; available in PMC 2013 Oct 5.

Published in final edited form as: Cell Stem Cell. 2012 Oct 5; 11(4): 505–516. Published online 2012 Aug 16. doi: 10.1016/j.stem.2012.06.006

PMCID:: PMC3466335

Abstract Article PDF–3.4M

Select item 327912217.

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma

Salil A. Lachke, Fowzan S. Alkuraya, Stephen C. Kneeland, Takbum Ohn, Anton Aboukhalil, Gareth R. Howell, Irfan Saadi, Resy Cavallesco, Yingzi Yue, Anne C-H. Tsai, K. Saidas Nair, Mihai I. Cosma, Richard S. Smith, Emily Hodges, Suad M. AlFadhli, Amal Al-Hajeri, Hanan E. Shamseldin, AbdulMutalib Behbehani, Gregory J. Hannon, Martha L. Bulyk, Arlene V. Drack, Paul J. Anderson, Simon W. M. John, Richard L. Maas

Science. Author manuscript; available in PMC 2012 Feb 14.

Published in final edited form as: Science. 2011 Mar 25; 331(6024): 1571–1576. doi: 10.1126/science.1195970

PMCID:: PMC3279122

Abstract Article PDF–2.6M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 306052119.

Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation

Ayako Watanabe, Megumi Tatematsu, Kazuko Saeki, Sachiko Shibata, Hiroaki Shime, Akihiko Yoshimura, Chikashi Obuse, Tsukasa Seya, Misako Matsumoto

J Biol Chem. 2011 Mar 25; 286(12): 10702–10711. Published online 2011 Jan 25. doi: 10.1074/jbc.M110.185793

PMCID:: PMC3060521

Abstract Article PDF–4.2M

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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