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Select item 114029101.

Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage

Sarah McNeilly, Cameron R. Thomson, Laura Gonzalez-Trueba, Yuan Yan Sin, Alessandra Granata, Graham Hamilton, Michelle Lee, Erin Boland, John D. McClure, Cristina Lumbreras-Perales, Alisha Aman, Apoorva A. Kumar, Marco Cantini, Caglar Gök, Delyth Graham, Yasuko Tomono, Christopher D. Anderson, Yinhui Lu, Colin Smith, Hugh S. Markus, Marc Abramowicz, Catheline Vilain, Rustam Al-Shahi Salman, Manuel Salmeron-Sanchez, Atticus H. Hainsworth, William Fuller, Karl E. Kadler, Neil J. Bulleid, Tom Van Agtmael

eBioMedicine. 2024 Sep; 107: 105315. Published online 2024 Aug 30. doi: 10.1016/j.ebiom.2024.105315

PMCID:: PMC11402910

Abstract Article PDF–2.3M

Select item 113659542.

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation

Vaishali N. Patel, Marit H. Aure, Sophie H. Choi, James R. Ball, Ethan D. Lane, Zhangjie Wang, Yongmei Xu, Changyu Zheng, Xibao Liu, Daniel Martin, Jillian Y. Pailin, Michaela Prochazkova, Ashok B. Kulkarni, Toin H. van Kuppevelt, Indu S. Ambudkar, Jian Liu, Matthew P. Hoffman

Nat Commun. 2024; 15: 7584. Published online 2024 Aug 31. doi: 10.1038/s41467-024-51862-0

Correction in:: Nat Commun. 2024; 15: 8784.

PMCID:: PMC11365954

Abstract Article PDF–5.0M

Select item 113583833.

Non-apical mitoses contribute to cell delamination during mouse gastrulation

Evangéline Despin-Guitard, Viviane S. Rosa, Steffen Plunder, Navrita Mathiah, Kristof Van Schoor, Eliana Nehme, Sara Merino-Aceituno, Joaquim Egea, Marta N. Shahbazi, Eric Theveneau, Isabelle Migeotte

Nat Commun. 2024; 15: 7364. Published online 2024 Aug 28. doi: 10.1038/s41467-024-51638-6

PMCID:: PMC11358383

Abstract Article PDF–5.4M

Select item 112611514.

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells

Liya Wang, Li He, Weijia Yi, Min Wang, Fangmin Xu, Hanlin Liu, Jiahui Nie, Yi-Hsuan Pan, Suying Dang, Wei Zhang

iScience. 2024 Jul 19; 27(7): 110273. Published online 2024 Jun 14. doi: 10.1016/j.isci.2024.110273

PMCID:: PMC11261151

Abstract Article PDF–3.4M

Select item 110901425.

TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

Mao Mao, Yien-Ming Kuo, Alfred K. Yu, Cassandre Labelle-Dumais, Yvonne Ou, Douglas B. Gould

Invest Ophthalmol Vis Sci. 2024 May; 65(5): 15. Published online 2024 May 8. doi: 10.1167/iovs.65.5.15

PMCID:: PMC11090142

Abstract Article PDF–13M

Select item 110417016.

A brain-specific angiogenic mechanism enabled by tip cell specialization

Giel Schevenels, Pauline Cabochette, Michelle America, Arnaud Vandenborne, Line De Grande, Stefan Guenther, Liqun He, Marc Dieu, Basile Christou, Marjorie Vermeersch, Raoul F. V. Germano, David Perez-Morga, Patricia Renard, Maud Martin, Michael Vanlandewijck, Christer Betsholtz, Benoit Vanhollebeke

Nature. 2024; 628(8009): 863–871. Published online 2024 Apr 3. doi: 10.1038/s41586-024-07283-6

PMCID:: PMC11041701

Abstract Article PDF–79M

Select item 108228197.

GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression

Hong Soon Kang, Sara A. Grimm, Xiao-Hui Liao, Anton M. Jetten

Cell Mol Life Sci. 2024 Dec; 81(1): 65. Published online 2024 Jan 28. doi: 10.1007/s00018-024-05113-6

PMCID:: PMC10822819

Abstract Article PDF–5.8M

Select item 107268488.

Impaired intracellular Ca²⁺ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice

Evan Yamasaki, Pratish Thakore, Sher Ali, Alfredo Sanchez Solano, Xiaowei Wang, Xiao Gao, Cassandre Labelle-Dumais, Myriam M. Chaumeil, Douglas B. Gould, Scott Earley

Sci Signal. Author manuscript; available in PMC 2024 May 14.

Published in final edited form as: Sci Signal. 2023 Nov 14; 16(811): eadi3966. Published online 2023 Nov 14. doi: 10.1126/scisignal.adi3966

PMCID:: PMC10726848

Abstract Article PDF–1.2M

Select item 106978249.

An mTurq2-Col4a1 mouse model allows for live visualization of mammalian basement membrane development

Rebecca A. Jones, Brandon Trejo, Parijat Sil, Katherine A. Little, H. Amalia Pasolli, Bradley Joyce, Eszter Posfai, Danelle Devenport

J Cell Biol. 2024 Feb 5; 223(2): e202309074. Published online 2023 Dec 5. doi: 10.1083/jcb.202309074

PMCID:: PMC10697824

Abstract Article PDF–7.3M

Select item 1069010910.

Netrin 1 directs vascular patterning and maturity in the developing kidney

Samuel E. Honeycutt, Pierre-Emmanuel Y. N'Guetta, Deanna M. Hardesty, Yubin Xiong, Shamus L. Cooper, Matthew J. Stevenson, Lori L. O'Brien

Development. 2023 Nov 15; 150(22): dev201886. Published online 2023 Nov 24. doi: 10.1242/dev.201886

PMCID:: PMC10690109

Abstract Article

Select item 1041075311.

Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice

Mao Mao, Cassandre Labelle-Dumais, Sara F. Tufa, Douglas R. Keene, Douglas B. Gould

Matrix Biol. Author manuscript; available in PMC 2023 Aug 9.

Published in final edited form as: Matrix Biol. 2022 Jun; 110: 151–173. Published online 2022 May 4. doi: 10.1016/j.matbio.2022.05.001

PMCID:: PMC10410753

Abstract Article PDF–2.2M

Select item 1039352812.

Elevated TGFβ Signaling Contributes to Cerebral Small Vessel Disease in Mouse Models of Gould Syndrome

Kayla Branyan, Cassandre Labelle-Dumais, Xiaowei Wang, Genki Hayashi, Bryson Lee, Zoe Peltz, Seán Gorman, Bo Qiao Li, Mao Mao, Douglas B. Gould

Matrix Biol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Matrix Biol. 2023 Jan; 115: 48–70. Published online 2022 Nov 23. doi: 10.1016/j.matbio.2022.11.007

PMCID:: PMC10393528

Abstract Article PDF–3.0M

Select item 1002713813.

Nephronectin is required to maintain right lung lobar separation during embryonic development

Carole L. Wilson, Chi F. Hung, Brian M. Burkel, Suzanne M. Ponik, Sina A. Gharib, Lynn M. Schnapp

Am J Physiol Lung Cell Mol Physiol. 2023 Mar 1; 324(3): L335–L344. Published online 2023 Jan 31. doi: 10.1152/ajplung.00505.2021

PMCID:: PMC10027138

Abstract Article

Select item 994597714.

Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome

Evan Yamasaki, Sher Ali, Alfredo Sanchez Solano, Pratish Thakore, Megan Smith, Xiaowei Wang, Cassandre Labelle-Dumais, Douglas B. Gould, Scott Earley

Proc Natl Acad Sci U S A. 2023 Jan 31; 120(5): e2217327120. Published online 2023 Jan 24. doi: 10.1073/pnas.2217327120

PMCID:: PMC9945977

Abstract Article PDF–2.7M

Select item 971329615.

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut

Rana Ramadan, Valérie M. Wouters, Sanne M. van Neerven, Nina E. de Groot, Tania Martins Garcia, Vanessa Muncan, Olivia D. Franklin, Michelle Battle, Karen Sue Carlson, Joshua Leach, Owen J. Sansom, Olivier Boulard, Mathias Chamaillard, Louis Vermeulen, Jan Paul Medema, David J. Huels

Biol Open. 2022 Dec 15; 11(12): bio059544. Published online 2022 Nov 23. doi: 10.1242/bio.059544

PMCID:: PMC9713296

Abstract Article PDF–3.6M

Select item 935276516.

Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis

Mostafa Bakhti, Aimée Bastidas-Ponce, Sophie Tritschler, Oliver Czarnecki, Marta Tarquis-Medina, Eva Nedvedova, Jessica Jaki, Stefanie J. Willmann, Katharina Scheibner, Perla Cota, Ciro Salinno, Karsten Boldt, Nicola Horn, Marius Ueffing, Ingo Burtscher, Fabian J. Theis, Ünal Coskun, Heiko Lickert

Nat Commun. 2022; 13: 4540. Published online 2022 Aug 4. doi: 10.1038/s41467-022-31862-8

PMCID:: PMC9352765

Abstract Article PDF–15M

Select item 898262217.

Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo

Wallis Nahaboo, Sema Elif Eski, Evangéline Despin‐Guitard, Marjorie Vermeersch, Marie Versaevel, Bechara Saykali, Daniel Monteyne, Sylvain Gabriele, Thomas M Magin, Nicole Schwarz, Rudolf E Leube, An Zwijsen, David Perez‐Morga, Sumeet Pal Singh, Isabelle Migeotte

EMBO J. 2022 Apr; 41(7): e108747. Published online 2022 Mar 10. doi: 10.15252/embj.2021108747

PMCID:: PMC8982622

Abstract Article PDF–8.0M

Select item 888174118.

ECM-integrin signalling instructs cellular position sensing to pattern the early mouse embryo

Esther Jeong Yoon Kim, Lydia Sorokin, Takashi Hiiragi

Development. 2022 Jan 1; 149(1): dev200140. Published online 2022 Jan 13. doi: 10.1242/dev.200140

PMCID:: PMC8881741

Abstract Article

Select item 879803919.

Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

John Darby Cole, Jacobo Sarabia del Castillo, Gabriele Gut, Daniel Gonzalez-Bohorquez, Lucas Pelkmans, Sebastian Jessberger

eLife. 2022; 11: e68000. Published online 2022 Jan 28. doi: 10.7554/eLife.68000

PMCID:: PMC8798039

Abstract Article PDF–9.5M

Select item 872239020.

A single-cell atlas of mouse lung development

Nicholas M. Negretti, Erin J. Plosa, John T. Benjamin, Bryce A. Schuler, A. Christian Habermann, Christopher S. Jetter, Peter Gulleman, Claire Bunn, Alice N. Hackett, Meaghan Ransom, Chase J. Taylor, David Nichols, Brittany K. Matlock, Susan H. Guttentag, Timothy S. Blackwell, Nicholas E. Banovich, Jonathan A. Kropski, Jennifer M. S. Sucre

Development. 2021 Dec 15; 148(24): dev199512. Published online 2021 Dec 20. doi: 10.1242/dev.199512

PMCID:: PMC8722390

Abstract Article

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